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Molecular and Clinical Oncology
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October-2019 Volume 11 Issue 4

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Article

The impact of pulmonary metastasectomy from gastric cancer

  • Authors:
    • Yohei Oguri
    • Masayuki Okui
    • Takashi Yamamichi
    • Ayaka Asakawa
    • Masahiko Harada
    • Hirotoshi Horio
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo 113‑8677, Japan
  • Pages: 401-404
    |
    Published online on: August 12, 2019
       https://doi.org/10.3892/mco.2019.1910
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Abstract

Gastric cancer remains the most commonly‑occurring cancer and the third most frequent cause of cancer‑associated mortality in Japan. Solitary pulmonary metastasis of gastric cancer is rare and the outcome of pulmonary metastasectomy is still unclear. Herein we report the impact of pulmonary resection in patients with metastasis from gastric cancer. The present study retrospectively reviewed the preoperative data and clinical courses of 10 patients who underwent pulmonary resection for metastasis from gastric cancer at our institution between July 1986 and December 2017. The data on the outcomes, including morbidity, mortality and survival, were obtained from the patient records. All patients were followed‑up from the time of pulmonary resection until mortality or referral to another hospital. The statistical analyses were performed using EZR (Saitama Medical Center, Jichi Medical University, Saitama, Japan), which is a graphical user interface for the R software program (The R Foundation for Statistical Computing, Vienna, Austria). The study population included 7 male patients and 3 female patients. A total of 5 patients underwent total gastrectomy, and 5 underwent distal gastrectomy. The median disease‑free interval after initial gastric resection was 34.5 months. Five patients received adjuvant chemotherapy, of the 10 thoracotomies, 5 were lobectomy, 3 were wedge resection and 2 were segmentectomy. The median overall survival following pulmonary metastasectomy was 59 months and the 5‑year survival rate was 40.5%. Taken together, the results of the present study suggest that pulmonary resection may be an effective therapeutic option for metastatic gastric cancer when a patient has a solitary metastatic lesion.
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Copy and paste a formatted citation
Spandidos Publications style
Oguri Y, Okui M, Yamamichi T, Asakawa A, Harada M and Horio H: The impact of pulmonary metastasectomy from gastric cancer. Mol Clin Oncol 11: 401-404, 2019.
APA
Oguri, Y., Okui, M., Yamamichi, T., Asakawa, A., Harada, M., & Horio, H. (2019). The impact of pulmonary metastasectomy from gastric cancer. Molecular and Clinical Oncology, 11, 401-404. https://doi.org/10.3892/mco.2019.1910
MLA
Oguri, Y., Okui, M., Yamamichi, T., Asakawa, A., Harada, M., Horio, H."The impact of pulmonary metastasectomy from gastric cancer". Molecular and Clinical Oncology 11.4 (2019): 401-404.
Chicago
Oguri, Y., Okui, M., Yamamichi, T., Asakawa, A., Harada, M., Horio, H."The impact of pulmonary metastasectomy from gastric cancer". Molecular and Clinical Oncology 11, no. 4 (2019): 401-404. https://doi.org/10.3892/mco.2019.1910
Copy and paste a formatted citation
x
Spandidos Publications style
Oguri Y, Okui M, Yamamichi T, Asakawa A, Harada M and Horio H: The impact of pulmonary metastasectomy from gastric cancer. Mol Clin Oncol 11: 401-404, 2019.
APA
Oguri, Y., Okui, M., Yamamichi, T., Asakawa, A., Harada, M., & Horio, H. (2019). The impact of pulmonary metastasectomy from gastric cancer. Molecular and Clinical Oncology, 11, 401-404. https://doi.org/10.3892/mco.2019.1910
MLA
Oguri, Y., Okui, M., Yamamichi, T., Asakawa, A., Harada, M., Horio, H."The impact of pulmonary metastasectomy from gastric cancer". Molecular and Clinical Oncology 11.4 (2019): 401-404.
Chicago
Oguri, Y., Okui, M., Yamamichi, T., Asakawa, A., Harada, M., Horio, H."The impact of pulmonary metastasectomy from gastric cancer". Molecular and Clinical Oncology 11, no. 4 (2019): 401-404. https://doi.org/10.3892/mco.2019.1910
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