Spontaneous healing of rectal penetration by SpaceOAR® hydrogel insertion during permanent iodine‑125 implant brachytherapy: A case report

Iinuma,Koji; Mizutani,Kosuke; Kato,Taku; Nakane,Keita; Tanaka,Hidekazu; Nakano,Masahiro; Matsuo,Masayuki; Koie,Takuya

doi:10.3892/mco.2019.1937

December-2019 Volume 11 Issue 6

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December-2019 Volume 11 Issue 6

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Case Report Open Access

Spontaneous healing of rectal penetration by SpaceOAR® hydrogel insertion during permanent iodine‑125 implant brachytherapy: A case report

Authors:
- Koji Iinuma
- Kosuke Mizutani
- Taku Kato
- Keita Nakane
- Hidekazu Tanaka
- Masahiro Nakano
- Masayuki Matsuo
- Takuya Koie
View Affiliations / Copyright

Affiliations: Department of Urology, Gifu University Graduate School of Medicine, Gifu 501‑1194, Japan, Department of Radiology, Gifu University Graduate School of Medicine, Gifu 501‑1194, Japan, Department of Urology, Gifu Prefectural General Medical Center, Gifu 500-8717, Japan

Copyright: © Iinuma et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Pages: 580-582
|
Published online on: October 15, 2019

https://doi.org/10.3892/mco.2019.1937
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Abstract

Radiation therapy with permanent iodine‑125 implant brachytherapy is well established for curable prostate cancer. To maximize the therapeutic potential of brachytherapy, delivered radiation doses have been increased accompanied by refined intraoperative procedures of radioactive seeds placement. However, dose escalation is a double-edged sword in prostate brachytherapy; it could induce rectal toxicity, yet is successful in curable treatment in prostate cancer. To reduce irradiation of the rectum, the SpaceOAR® system has been used to inject synthetic polyethylene glycol hydrogel between the prostate and the rectum. The present report describes a case of spontaneous healing of rectal penetration associated with SpaceOAR® hydrogel.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Spontaneous healing of rectal penetration by SpaceOAR® hydrogel insertion during permanent iodine‑125 implant brachytherapy: A case report

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