Open Access

Male patient with metastatic stage IV breast cancer achieves complete remission on second line Abemaciclib, Fulvestrant and Leuprolide: A case report

  • Authors:
    • Damien Hansra
    • Shirelle Jackson
    • Judy Sequeira
    • Rajendra Vazirani
    • Ricardo Alvarez
  • View Affiliations

  • Published online on: November 29, 2019     https://doi.org/10.3892/mco.2019.1955
  • Pages: 120-125
  • Copyright: © Hansra et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Male breast cancer occurs rarely, comprising <1% of breast cancers. Due to the low incidence of male breast cancer, clinical trials of this disease are lacking. Therefore, therapeutic strategies utilized in the management of female breast cancer are often applied to male patients with breast cancer. Specifically, clinical outcomes using CDK 4/6 inhibitors require further investigation in male patients. To the best of our knowledge, the present report presents the first known case of a male patient treated with second line Abemaciclib, Lupron and Fulvestrant, producing complete remission. To the best of our knowledge this is also the first report of complete remission in a male breast cancer patient with a regimen utilizing a CDK 4/6 inhibitor.
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February-2020
Volume 12 Issue 2

Print ISSN: 2049-9450
Online ISSN:2049-9469

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Spandidos Publications style
Hansra D, Jackson S, Sequeira J, Vazirani R and Alvarez R: Male patient with metastatic stage IV breast cancer achieves complete remission on second line Abemaciclib, Fulvestrant and Leuprolide: A case report. Mol Clin Oncol 12: 120-125, 2020
APA
Hansra, D., Jackson, S., Sequeira, J., Vazirani, R., & Alvarez, R. (2020). Male patient with metastatic stage IV breast cancer achieves complete remission on second line Abemaciclib, Fulvestrant and Leuprolide: A case report. Molecular and Clinical Oncology, 12, 120-125. https://doi.org/10.3892/mco.2019.1955
MLA
Hansra, D., Jackson, S., Sequeira, J., Vazirani, R., Alvarez, R."Male patient with metastatic stage IV breast cancer achieves complete remission on second line Abemaciclib, Fulvestrant and Leuprolide: A case report". Molecular and Clinical Oncology 12.2 (2020): 120-125.
Chicago
Hansra, D., Jackson, S., Sequeira, J., Vazirani, R., Alvarez, R."Male patient with metastatic stage IV breast cancer achieves complete remission on second line Abemaciclib, Fulvestrant and Leuprolide: A case report". Molecular and Clinical Oncology 12, no. 2 (2020): 120-125. https://doi.org/10.3892/mco.2019.1955