Open Access

Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report

  • Authors:
    • Arianna Di Stadio
    • Valeria Gambacorta
    • Stefano De Crescenzo
    • Angelo Sidoni
    • Maria Cristina Cristi
    • Alfredo Di Giovanni
    • Massimo Maranzano
    • Giampietro Ricci
  • View Affiliations

  • Published online on: February 26, 2020     https://doi.org/10.3892/mco.2020.2007
  • Pages: 451-455
  • Copyright: © Di Stadio et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

A correlation between inflammation and cancer has been identified in the case of nasal cancer, however a specific connection between nasal inflammation and extramedullary nasal plasmacytoma (ENP), to the best of our knowledge, has not yet been determined. The present case report describes a patient affected by ENP, in who the tumor arose in the same area, from which a nasal polyp was previously surgically removed, five months after the polyp excision. The patient underwent surgical endoscopic tumor asportation without being treated with radio‑chemotherapy. ENP was totally removed via surgery and no signs of recurrence were identified by endoscopy or magnetic resonance imaging during the last check‑up 1 year after tumor asportation. It was hypothesized that in this elderly patient, who was exposed to viral infections and pollution for several years, ENP may be correlated to the inflammatory process that occurred after surgery, and this likely contributed to a neoplastic mutation in B‑cells.
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May 2020
Volume 12 Issue 5

Print ISSN: 2049-9450
Online ISSN:2049-9469

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APA
Di Stadio, A., Gambacorta, V., De Crescenzo, S., Sidoni, A., Cristi, M.C., Di Giovanni, A. ... Ricci, G. (2020). Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report. Molecular and Clinical Oncology, 12, 451-455. https://doi.org/10.3892/mco.2020.2007
MLA
Di Stadio, A., Gambacorta, V., De Crescenzo, S., Sidoni, A., Cristi, M. C., Di Giovanni, A., Maranzano, M., Ricci, G."Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report". Molecular and Clinical Oncology 12.5 (2020): 451-455.
Chicago
Di Stadio, A., Gambacorta, V., De Crescenzo, S., Sidoni, A., Cristi, M. C., Di Giovanni, A., Maranzano, M., Ricci, G."Extramedullary nasal plasmacytoma arising after polyp excision and the role of the inflammation in tumor development: A case report". Molecular and Clinical Oncology 12, no. 5 (2020): 451-455. https://doi.org/10.3892/mco.2020.2007