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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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May-2020 Volume 12 Issue 5

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International Journal of Molecular Medicine

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Review

Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review)

  • Authors:
    • Kalliopi Alpantaki
    • Argyrios Ioannidis
    • Konstantinos Raptis
    • Eleftherios Spartalis
    • Christos Koutserimpas
  • View Affiliations / Copyright

    Affiliations: Department of Orthopaedics, ‘Venizeleion’ General Hospital, Heraklion, Crete 71409, Greece, Department of General, Laparoscopic, Oncologic and Robotic Surgery, Athens Medical Center, Athens 15125, Greece, Department of Orthopaedics and Traumatology, ‘251’ Hellenic Air Force General Hospital, Athens 11525, Greece, Laboratory of Experimental Surgery and Surgical Research, University of Athens Medical School, Athens 11527, Greece
  • Pages: 399-402
    |
    Published online on: February 27, 2020
       https://doi.org/10.3892/mco.2020.2008
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Abstract

The management of spinal metastatic tumors is a matter of increasing clinical importance, as 20‑40% of cancer patients have evidence of vertebral metastatic disease at the time of their passing and up to 20% develop neurological symptoms due to epidural spinal cord compression. The treatment of patients with spinal metastases is challenging, albeit palliative, and it requires a multidisciplinary approach. Accurate prediction of life expectancy of patients with cancer is of paramount importance for therapeutic strategy. Prognostication scoring systems were developed to aid clinicians to follow a more objective, safe and evidence‑based approach with therapy selection and surgical intervention indications. In this context, the aim of the present review was to briefly discuss the evolution of scoring systems since their introduction in the early 90s until today, their advantages and shortcomings, and the future requirements for personalized scoring in the era of modern oncology.
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1 

Barzilai O, Fisher CG and Bilsky MH: State of the Art treatment of spinal metastatic disease. Neurosurgery. 82:757–769. 2018.PubMed/NCBI View Article : Google Scholar

2 

Delank KS, Wendtner C, Eich HT and Eysel P: The treatment of spinal metastases. Dtsch Arztebl Int. 108:71–80. 2011.PubMed/NCBI View Article : Google Scholar

3 

Papastefanou S, Alpantaki K, Akra G and Katonis P: Predictive value of Tokuhashi and Tomita scores in patients with metastatic spine disease. Acta Orthop Traumatol Turc. 46:50–56. 2012.PubMed/NCBI View Article : Google Scholar

4 

Deng Z, Xu B, Jin J, Zhao J and Xu H: Strategies for management of spinal metastases: A comprehensive review. Cancer Transl Med. 1:94–100. 2015.

5 

Klimo P Jr, Thompson CJ, Kestle JR and Schmidt MH: A meta-analysis of surgery versus conventional radiotherapy for the treatment of metastatic spinal epidural disease. Neuro Oncol. 7:64–76. 2006.PubMed/NCBI View Article : Google Scholar

6 

Jansson KA and Bauer HC: Survival, complications and outcome in 282 patients operated for neurological deficit due to thoracic or lumbar spinal metastases. Eur Spine J. 15:196–202. 2006.PubMed/NCBI View Article : Google Scholar

7 

Tokuhashi Y, Uei H, Oshima M and Ajiro Y: Scoring system for prediction of metastatic spine tumor prognosis. World J Orthop. 5:262–271. 2014.PubMed/NCBI View Article : Google Scholar

8 

Ragel BT, Mendez GA, Reddington J, Ferachi D, Kubicky CD, Philipp TC, Zusman NL, Klimo P, Hart R, Yoo J and Ching AC: Life expectancy and metastatic spine scoring systems: An academic institutional experience. Clin Spine Surg. 30:335–342. 2017.PubMed/NCBI View Article : Google Scholar

9 

Cassidy JT, Baker JF and Lenehan B: The role of prognostic scoring systems in assessing surgical candidacy for patients with vertebral metastasis: A narrative review. Global Spine J. 8:638–651. 2018.PubMed/NCBI View Article : Google Scholar

10 

Engelhardt EG, Révész D, Tamminga HJ, Punt CJA, Koopman M, Onwuteaka-Philipsen BD, Steyerberg EW, Jansma IP, De Vet HCW and Coupé VMH: Clinical usefulness of tools to support decision-making for palliative treatment of metastatic colorectal cancer: A systematic review clinical colorectal cancer. Clin Colorectal Cancer. 17:e1–e12. 2018.PubMed/NCBI View Article : Google Scholar

11 

Tokuhashi Y, Matsuzaki H, Toriyama S, Kawano H and Ohsaka S: Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine (Phila Pa 1976). 15:1110–1113. 1990.PubMed/NCBI View Article : Google Scholar

12 

Tomita K, Kawahara N, Kobayashi T, Yoshida A, Murakami H and Akamaru T: Surgical strategy of spinal metastases. Spine (Phila Pa 1976). 26:298–306. 2001.

13 

Joaquim AF, Powers A, Laufer I and Bilsky MH: An update in the management of spinal metastases. Arq Neuropsiquiatr. 73:795–802. 2015.PubMed/NCBI View Article : Google Scholar

14 

Laufer I, Rubin DG, Lis E, Cox BW, Stubblefield MD, Yamada Y and Bilsky MH: The NOMS framework: Approach to the treatment of spinal metastatic tumors. Oncologist. 18:744–751. 2013.PubMed/NCBI View Article : Google Scholar

15 

Fourney DR, Frangou EM, Ryken TC, Dipaola CP, Shaffrey CI, Berven SH, Bilsky MH, Harrop JS, Fehlings MG, Boriani S, et al: Spinal instability neoplastic score: An analysis of reliability and validity from the spine oncology study group. J Clin Oncol. 29:3072–3077. 2011.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Alpantaki K, Ioannidis A, Raptis K, Spartalis E and Koutserimpas C: Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review). Mol Clin Oncol 12: 399-402, 2020.
APA
Alpantaki, K., Ioannidis, A., Raptis, K., Spartalis, E., & Koutserimpas, C. (2020). Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review). Molecular and Clinical Oncology, 12, 399-402. https://doi.org/10.3892/mco.2020.2008
MLA
Alpantaki, K., Ioannidis, A., Raptis, K., Spartalis, E., Koutserimpas, C."Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review)". Molecular and Clinical Oncology 12.5 (2020): 399-402.
Chicago
Alpantaki, K., Ioannidis, A., Raptis, K., Spartalis, E., Koutserimpas, C."Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review)". Molecular and Clinical Oncology 12, no. 5 (2020): 399-402. https://doi.org/10.3892/mco.2020.2008
Copy and paste a formatted citation
x
Spandidos Publications style
Alpantaki K, Ioannidis A, Raptis K, Spartalis E and Koutserimpas C: Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review). Mol Clin Oncol 12: 399-402, 2020.
APA
Alpantaki, K., Ioannidis, A., Raptis, K., Spartalis, E., & Koutserimpas, C. (2020). Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review). Molecular and Clinical Oncology, 12, 399-402. https://doi.org/10.3892/mco.2020.2008
MLA
Alpantaki, K., Ioannidis, A., Raptis, K., Spartalis, E., Koutserimpas, C."Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review)". Molecular and Clinical Oncology 12.5 (2020): 399-402.
Chicago
Alpantaki, K., Ioannidis, A., Raptis, K., Spartalis, E., Koutserimpas, C."Surgery for spinal metastatic tumors: Prognostication systems in clinical practice (Review)". Molecular and Clinical Oncology 12, no. 5 (2020): 399-402. https://doi.org/10.3892/mco.2020.2008
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