Mycosis fungoides and gastric T‑cell lymphoma: A case report

Scali,Elisabetta; Presta,Ivan; Donato,Annalidia; Schipani,Giusy; Dastoli,Stefano; Rossi,Marco; Mignogna,Chiara; Malara,Natalia; Nisticò,Steven Paul; Donato,Giuseppe

doi:10.3892/mco.2020.2085

Mycosis fungoides and gastric T‑cell lymphoma: A case report

Authors:
- Elisabetta Scali
- Ivan Presta
- Annalidia Donato
- Giusy Schipani
- Stefano Dastoli
- Marco Rossi
- Chiara Mignogna
- Natalia Malara
- Steven Paul Nisticò
- Giuseppe Donato
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Affiliations: Department of Health Sciences, University ‘Magna Græcia’ of Catanzaro, Catanzaro I‑88100, Italy, Department of Medical and Surgical Sciences, University ‘Magna Græcia’ of Catanzaro, Catanzaro I‑88100, Italy, Department of Clinical and Experimental Medicine, University ‘Magna Græcia’ of Catanzaro, Catanzaro I‑88100, Italy, Department of Interdipartimental Services Center (CIS), University ‘Magna Græcia’ of Catanzaro, Catanzaro I‑88100, Italy
Published online on: July 6, 2020 https://doi.org/10.3892/mco.2020.2085
Article Number: 15
Copyright: © Scali et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Mycosis fungoides (MF) is a cutaneous malignant lymphoma with an extended clinical course. MF presents in series of dermatological manifestations, beginning with patches and plaques of the skin, and eventually evolving into tumours. Often MF can occur for extended periods without worsening of external symptoms, while the disease advances internally in organs such as lymph nodes, liver, spleen, lung, bone marrow, gastrointestinal tract, pancreas and kidney. The present report presents a clinical case in which gastrointestinal symptomatology occurred a decade after the first dermatological manifestation. Immunohistochemical analysis of the skin, along with small bowel biopsies revealed evidence of gastric T‑cell lymphoma. To the best of our knowledge, the present study is the first to describe such a case in the literature.

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