Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular and Clinical Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 2049-9450 Online ISSN: 2049-9469
Journal Cover
October-2020 Volume 13 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2020 Volume 13 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Implementation of primary HPV testing in Japan

  • Authors:
    • Tetsuji Kurokawa
    • Yoshio Yoshida
    • Osamu Iwanari
    • Tetsuro Oishi
    • Tokuzo Kasai
    • Masao Hamada
    • Hiromasa Fujita
    • Hiroyuki Fujiwara
    • Masatoshi Yokoyama
    • Noriaki Sakuragi
    • Junzo Kigawa
    • Mitsuaki Suzuki
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Fukui, Fukui 910‑1193, Japan, Department of Obstetrics and Gynecology, Shimane Prefectural Central Hospital, Izumo, Shimane 693‑8555, Japan, Department of Obstetrics and Gynecology, Tottori University, Yonago, Tottori 683‑8504, Japan, Chiba Foundation for Health Promotion and Disease Prevention, Chiba 261‑0002, Japan, Hamada Ladies Clinic, Miyazaki 880‑0121, Japan, Hokkaido Cancer Society, Sapporo, Hokkaido 065‑0026, Japan, Department of Obstetrics and Gynecology, Jichi Medical University, Shimotsuke, Tochigi 329‑0498, Japan, Department of Obstetrics and Gynecology, University of Saga, Saga 849‑8501, Japan, Department of Obstetrics and Gynecology, Otaru General Hospital, Otaru, Hokkaido 047‑8550, Japan, Department of Obstetrics and Gynecology, Matsue City Hospital, Matsue, Shimane 690‑8509, Japan, Department of Obstetrics and Gynecology, Shinyurigaoka General Hospital, Kawasaki, Kanagawa 215‑0026, Japan
    Copyright: © Kurokawa et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 22
    |
    Published online on: July 16, 2020
       https://doi.org/10.3892/mco.2020.2092
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Cervical cancer screening has been shifting from primary cytology to primary HPV testing worldwide as primary HPV testing is more sensitive than primary cytology. To the best of our knowledge, the current study is the first in Japan to examine the feasibility of primary HPV testing. One of the disadvantages of this shift is that hrHPV‑/≥LSIL/CIN2+ (high‑risk HPV negative cancers or pre‑cancerous lesions with abnormal cytology results) can be missed. The objectives of the present study are to clarify in detail CIN2+ missed by this shift and to evaluate the feasibility of primary HPV testing in Japan. Data from 115,273 women who underwent co‑testing with cytology and HPV testing in cancer screening were used in the current study. The cases with hrHPV‑/≥LSIL (‘hrHPV‑/≥L‑SIL’ include CIN2‑, in contrast, ‘hrHPV‑/≥L‑SIL/CIN2+’ doesn't include CIN2‑) were analysed in detail. Women with hrHPV‑/≥LSIL comprised 0.3% of the total. The prevalence of CIN2, CIN3, SCC or cervical adenocarcinomas in the lesions with HPV‑/≥LSIL was 0.03% in the cancer screening group. Only one case of 14 cervical adenocarcinomas in ≥LSIL was hrHPV‑. The prevalence of cancer missed by the shift in patients >50 years of age was significantly higher compared with patients younger than 49 years. In conclusion, the prevalence of CIN2+, which might be missed by the shift from primary cytology to primary HPV testing, was remarkably low in this Japanese cancer screening. The data indicated that primary HPV testing, which was more sensitive for CIN2+ than primary cytology, was a feasible method that can be used in Japan. In particular, primary HPV testing should be introduced for women <50 years old.
View Figures
View References

1 

Ferlay J, Colombet M, Soerjomataram I, Mathers C, Parkin DM, Piñeros M, Znaor A and Bray F: Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. Int J Cancer. 144:1941–1953. 2019.PubMed/NCBI View Article : Google Scholar

2 

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68:394–424. 2018.PubMed/NCBI View Article : Google Scholar

3 

Konno R, Konishi H, Sauvaget C, Ohashi Y and Kakizoe T: Effectiveness of HPV vaccination against high grade cervical lesions in Japan. Vaccine. 36:7913–7915. 2018.PubMed/NCBI View Article : Google Scholar

4 

US Preventive Services Task Force. Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, Davidson KW, Doubeni CA, Epling JW Jr, Kemper AR, et al: Screening for cervical cancer: US preventive services task force recommendation statement. JAMA. 320:674–686. 2018.PubMed/NCBI View Article : Google Scholar

5 

Ogilvie GS, van Niekerk D, Krajden M, Smith LW, Cook D, Gondara L, Ceballos K, Quinlan D, Lee M, Martin RE, et al: Effect of screening with primary cervical HPV testing vs cytology testing on high-grade cervical intraepithelial neoplasia at 48 months: The HPV FOCAL randomized clinical trial. JAMA. 320:43–52. 2018.PubMed/NCBI View Article : Google Scholar

6 

Ronco G, Giorgi-Rossi P, Carozzi F, Confortini M, Dalla Palma P, Del Mistro A, Ghiringhello B, Girlando S, Gillio-Tos A, De Marco L, et al: Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: A randomised controlled trial. Lancet Oncol. 11:249–257. 2010.PubMed/NCBI View Article : Google Scholar

7 

Ronco G, Giorgi-Rossi P, Carozzi F, Dalla Palma P, Del Mistro A, De Marco L, De Lillo M, Naldoni C, Pierotti P, Rizzolo R, et al: Human papillomavirus testing and liquid-based cytology in primary screening of women younger than 35 years: Results at recruitment for a randomised controlled trial. Lancet Oncol. 7:547–555. 2006.PubMed/NCBI View Article : Google Scholar

8 

Ronco G, Segnan N, Giorgi-Rossi P, Zappa M, Casadei GP, Carozzi F, Dalla Palma P, Del Mistro A, Folicaldi S, Gillio-Tos A, et al: Human papillomavirus testing and liquid-based cytology: Results at recruitment from the new technologies for cervical cancer randomized controlled trial. J Natl Cancer Inst. 98:765–774. 2006.PubMed/NCBI View Article : Google Scholar

9 

Ronco G, Giorgi-Rossi P, Carozzi F, Confortini M, Dalla Palma P, Del Mistro A, Gillio-Tos A, Minucci D, Naldoni C, Rizzolo R, et al: Results at recruitment from a randomized controlled trial comparing human papillomavirus testing alone with conventional cytology as the primary cervical cancer screening test. J Natl Cancer Inst. 100:492–501. 2008.PubMed/NCBI View Article : Google Scholar

10 

Ogilvie GS, Krajden M, van Niekerk D, Smith LW, Cook D, Ceballos K, Lee M, Gentile L, Gondara L, Elwood-Martin R, et al: HPV for cervical cancer screening (HPV FOCAL): Complete Round 1 results of a randomized trial comparing HPV-based primary screening to liquid-based cytology for cervical cancer. Int J Cancer. 140:440–448. 2017.PubMed/NCBI View Article : Google Scholar

11 

Leinonen MK, Nieminen P, Lönnberg S, Malila N, Hakama M, Pokhrel A, Laurila P, Tarkkanen J and Anttila A: Detection rates of precancerous and cancerous cervical lesions within one screening round of primary human papillomavirus DNA testing: Prospective randomised trial in Finland. BMJ. 345(e7789)2012.PubMed/NCBI View Article : Google Scholar

12 

Canfell K, Caruana M, Gebski V, Darlington-Brown J, Heley S, Brotherton J, Gertig D, Jennett CJ, Farnsworth A, Tan J, et al: Cervical screening with primary HPV testing or cytology in a population of women in which those aged 33 years or younger had previously been offered HPV vaccination: Results of the Compass pilot randomised trial. PLoS Med. 14(e1002388)2017.PubMed/NCBI View Article : Google Scholar

13 

Solomon D, Davey D, Kurman R, Moriarty A, O'Connor D, Prey M, Raab S, Sherman M, Wilbur D, Wright T Jr, et al: The 2001 Bethesda System: Terminology for reporting results of cervical cytology. JAMA. 287:2114–2119. 2002.PubMed/NCBI View Article : Google Scholar

14 

Ki EY, Lee YK, Lee A and Park JS: Comparison of the PANArray HPV genotyping chip test with the Cobas 4800 HPV and hybrid capture 2 tests for detection of HPV in ASCUS women. Yonsei Med J. 59:662–668. 2018.PubMed/NCBI View Article : Google Scholar

15 

Sauvaget C, Nishino Y, Konno R, Tase T, Morimoto T and Hisamichi S: Challenges in breast and cervical cancer control in Japan. Lancet Oncol. 17:e305–e312. 2016.PubMed/NCBI View Article : Google Scholar

16 

Kurokawa T, Onuma T, Shinagawa A, Chino Y, Kobayashi M and Yoshida Y: The ideal strategy for cervical cancer screening in Japan: Result from the Fukui cervical cancer screening study. Cytopathology. 29:361–367. 2018.PubMed/NCBI View Article : Google Scholar

17 

Tjalma W: HPV negative cervical cancers and primary HPV screening. Facts Views Vis Obgyn. 10:107–113. 2018.PubMed/NCBI

18 

Clifford GM, Smith JS, Aguado T and Franceschi S: Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: A meta-analysis. Br J Cancer. 89:101–105. 2003.PubMed/NCBI View Article : Google Scholar

19 

Guan P, Howell-Jones R, Li N, Bruni L, de Sanjosé S, Franceschi S and Clifford GM: Human papillomavirus types in 115,789 HPV-positive women: A meta-analysis from cervical infection to cancer. Int J Cancer. 131:2349–2359. 2012.PubMed/NCBI View Article : Google Scholar

20 

Onuki M, Matsumoto K, Satoh T, Oki A, Okada S, Minaguchi T, Ochi H, Nakao S, Someya K, Yamada N, et al: Human papillomavirus infections among Japanese women: Age-related prevalence and type-specific risk for cervical cancer. Cancer Sci. 100:1312–1316. 2009.PubMed/NCBI View Article : Google Scholar

21 

Kitchener HC, Almonte M, Wheeler P, Desai M, Gilham C, Bailey A, Sargent A and Peto J: ARTISTIC Trial Study Group: HPV testing in routine cervical screening: Cross sectional data from the ARTISTIC trial. Br J Cancer. 95:56–61. 2006.PubMed/NCBI View Article : Google Scholar

22 

Kitchener HC, Gilham C, Sargent A, Bailey A, Albrow R, Roberts C, Desai M, Mather J, Turner A, Moss S and Peto J: A comparison of HPV DNA testing and liquid based cytology over three rounds of primary cervical screening: Extended follow up in the ARTISTIC trial. Eur J Cancer. 47:864–871. 2011.PubMed/NCBI View Article : Google Scholar

23 

Kitchener HC, Almonte M, Thomson C, Wheeler P, Sargent A, Stoykova B, Gilham C, Baysson H, Roberts C, Dowie R, et al: HPV testing in combination with liquid-based cytology in primary cervical screening (ARTISTIC): A randomised controlled trial. Lancet Oncol. 10:672–682. 2009.PubMed/NCBI View Article : Google Scholar

24 

Sargent A, Bailey A, Almonte M, Turner A, Thomson C, Peto J, Desai M, Mather J, Moss S, Roberts C, et al: Prevalence of type-specific HPV infection by age and grade of cervical cytology: Data from the ARTISTIC trial. Br J Cancer. 98:1704–1709. 2008.PubMed/NCBI View Article : Google Scholar

25 

Castle PE, Stoler MH, Wright TC Jr, Sharma A, Wright TL and Behrens CM: Performance of carcinogenic human papillomavirus (HPV) testing and HPV16 or HPV18 genotyping for cervical cancer screening of women aged 25 years and older: A subanalysis of the ATHENA study. Lancet Oncol. 12:880–890. 2011.PubMed/NCBI View Article : Google Scholar

26 

Cox JT, Castle PE, Behrens CM, Sharma A, Wright TC Jr and Cuzick J: Athena HPV Study Group: Comparison of cervical cancer screening strategies incorporating different combinations of cytology, HPV testing, and genotyping for HPV 16/18: Results from the ATHENA HPV study. Am J Obstet Gynecol. 208:184.e1–184.e11. 2013.PubMed/NCBI View Article : Google Scholar

27 

Monsonego J, Cox JT, Behrens C, Sandri M, Franco EL, Yap PS and Huh W: Prevalence of high-risk human papilloma virus genotypes and associated risk of cervical precancerous lesions in a large U.S. screening population: Data from the ATHENA trial. Gynecol Oncol. 137:47–54. 2015.PubMed/NCBI View Article : Google Scholar

28 

Petry KU, Cox JT, Johnson K, Quint W, Ridder R, Sideri M, Wright TC Jr and Behrens CM: Evaluating HPV-negative CIN2+ in the ATHENA trial. Int J Cancer. 138:2932–2939. 2016.PubMed/NCBI View Article : Google Scholar

29 

Wright TC Jr, Stoler MH, Behrens CM, Apple R, Derion T and Wright TL: The ATHENA human papillomavirus study: Design, methods, and baseline results. Am J Obstet Gynecol. 206:46.e1–46.e11. 2012.PubMed/NCBI View Article : Google Scholar

30 

Wright TC Jr, Stoler MH, Sharma A, Zhang G, Behrens C and Wright TL: ATHENA (Addressing THE Need for Advanced HPV Diagnostics) Study Group: Evaluation of HPV-16 and HPV-18 genotyping for the triage of women with high-risk HPV+ cytology-negative results. Am J Clin Pathol. 136:578–586. 2011.PubMed/NCBI View Article : Google Scholar

31 

Young RH and Clement PB: Endocervical adenocarcinoma and its variants: Their morphology and differential diagnosis. Histopathology. 41:185–207. 2002.PubMed/NCBI View Article : Google Scholar

32 

Schnatz PF, Guile M, O'Sullivan DM and Sorosky JI: Clinical significance of atypical glandular cells on cervical cytology. Obstet Gynecol. 107:701–708. 2006.PubMed/NCBI View Article : Google Scholar

33 

Lew JB, Simms KT, Smith MA, Hall M, Kang YJ, Xu XM, Caruana M, Velentzis LS, Bessell T, Saville M, et al: Primary HPV testing versus cytology-based cervical screening in women in Australia vaccinated for HPV and unvaccinated: Effectiveness and economic assessment for the national cervical screening program. Lancet Public Health. 2:e96–e107. 2017.PubMed/NCBI View Article : Google Scholar

34 

Canfell K, Saville M, Caruana M, Gebski V, Darlington-Brown J, Brotherton J, Heley S and Castle PE: Protocol for Compass: A randomised controlled trial of primary HPV testing versus cytology screening for cervical cancer in HPV-unvaccinated and vaccinated women aged 25-69 years living in Australia. BMJ Open. 8(e016700)2018.PubMed/NCBI View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Kurokawa T, Yoshida Y, Iwanari O, Oishi T, Kasai T, Hamada M, Fujita H, Fujiwara H, Yokoyama M, Sakuragi N, Sakuragi N, et al: Implementation of primary HPV testing in Japan. Mol Clin Oncol 13: 22, 2020.
APA
Kurokawa, T., Yoshida, Y., Iwanari, O., Oishi, T., Kasai, T., Hamada, M. ... Suzuki, M. (2020). Implementation of primary HPV testing in Japan. Molecular and Clinical Oncology, 13, 22. https://doi.org/10.3892/mco.2020.2092
MLA
Kurokawa, T., Yoshida, Y., Iwanari, O., Oishi, T., Kasai, T., Hamada, M., Fujita, H., Fujiwara, H., Yokoyama, M., Sakuragi, N., Kigawa, J., Suzuki, M."Implementation of primary HPV testing in Japan". Molecular and Clinical Oncology 13.4 (2020): 22.
Chicago
Kurokawa, T., Yoshida, Y., Iwanari, O., Oishi, T., Kasai, T., Hamada, M., Fujita, H., Fujiwara, H., Yokoyama, M., Sakuragi, N., Kigawa, J., Suzuki, M."Implementation of primary HPV testing in Japan". Molecular and Clinical Oncology 13, no. 4 (2020): 22. https://doi.org/10.3892/mco.2020.2092
Copy and paste a formatted citation
x
Spandidos Publications style
Kurokawa T, Yoshida Y, Iwanari O, Oishi T, Kasai T, Hamada M, Fujita H, Fujiwara H, Yokoyama M, Sakuragi N, Sakuragi N, et al: Implementation of primary HPV testing in Japan. Mol Clin Oncol 13: 22, 2020.
APA
Kurokawa, T., Yoshida, Y., Iwanari, O., Oishi, T., Kasai, T., Hamada, M. ... Suzuki, M. (2020). Implementation of primary HPV testing in Japan. Molecular and Clinical Oncology, 13, 22. https://doi.org/10.3892/mco.2020.2092
MLA
Kurokawa, T., Yoshida, Y., Iwanari, O., Oishi, T., Kasai, T., Hamada, M., Fujita, H., Fujiwara, H., Yokoyama, M., Sakuragi, N., Kigawa, J., Suzuki, M."Implementation of primary HPV testing in Japan". Molecular and Clinical Oncology 13.4 (2020): 22.
Chicago
Kurokawa, T., Yoshida, Y., Iwanari, O., Oishi, T., Kasai, T., Hamada, M., Fujita, H., Fujiwara, H., Yokoyama, M., Sakuragi, N., Kigawa, J., Suzuki, M."Implementation of primary HPV testing in Japan". Molecular and Clinical Oncology 13, no. 4 (2020): 22. https://doi.org/10.3892/mco.2020.2092
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team