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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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November-2020 Volume 13 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Article

Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method

  • Authors:
    • Shuichi Iwahashi
    • A. Ammar Ghaibeh
    • Mitsuo Shimada
    • Yuji Morine
    • Satoru Imura
    • Tetsuya Ikemoto
    • Yu Saito
    • Jun Hirose
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Institute of Health Biosciences, The University of Tokushima, Kuramoto‑cho, Tokushima 770‑8503, Japan, Department of Medical Informatics, Institute of Health Biosciences, The University of Tokushima, Kuramoto‑cho, Tokushima 770‑8503, Japan
  • Article Number: 46
    |
    Published online on: August 14, 2020
       https://doi.org/10.3892/mco.2020.2116
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Abstract

Hepatocellular carcinoma (HCC) is a highly lethal tumor and the majority of postoperative patients experience recurrence. In the present study, we focus on the predictability of postoperative recurrence on HCC through the data mining method. In total, 323 patients with HCC who underwent hepatic resection were included in the present study, 156 of whom suffered from cancer recurrence. Clinicopathological data including prognosis were analyzed using the data mining method for the predictability of postoperative recurrence on HCC. The resulting alternating decision tree (ADT) was described using data mining method. This tree was validated using a 10‑fold cross validation process. The average and standard deviation of the accuracy, sensitivity, and specificity were 69.0±8.2, 59.7±14.5 and 77.7±10.2%, respectively. The identified postoperative recurrence factors were age, viral hepatitis, stage, GOT and T‑cholesterol. Data mining method could identify the factors associated at different levels of significance with postoperative recurrence of HCC. These factors could help to predict the postoperative recurrence of HCC.
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1 

El Naqa I, Haider MA, Giger ML and Ten Haken RK: Artificial intelligence: Reshaping the practice of radiological sciences in the 21st century. Br J Radiol. 93(1106)2020.PubMed/NCBI View Article : Google Scholar

2 

Bellazzi R and Zupan B: Predictive data mining in clinical medicine: Current issues and guidelines. Int J Med Inform. 77:81–97. 2008.PubMed/NCBI View Article : Google Scholar

3 

Setoguchi Y, Ghaibeh AA, Mitani K, Abe Y, Hashimoto I and Moriguchi H: Predictability of pressure ulcers based on operation duration, transfer activity and body mass index through the use of an alternating decision tree. J Med Invest. 63:248–255. 2016.PubMed/NCBI View Article : Google Scholar

4 

Moreira LB and Namen AA: A hybrid data mining model for diagnosis of patients with clinical suspicion of dementia. Comput Methods Programs Biomed. 165:139–149. 2018.PubMed/NCBI View Article : Google Scholar

5 

Uemura H, Ghaibeh AA, Katsuura-Kamano S, Yamaguchi M, Bahari T, Ishizu M, Moriguchi H and Arisawa K: Systemic inflammation and family history in relation to the prevalence of type 2 diabetes based on an alternating decision tree. Sci Rep. 7(45502)2017.PubMed/NCBI View Article : Google Scholar

6 

Satomi J, Ghaibeh AA, Moriguchi H and Nagahiro S: Predictability of the future development of aggressive behavior of cranial dural arteriovenous fistulas based on decision tree analysis. J Neurosurg. 123:86–90. 2015.PubMed/NCBI View Article : Google Scholar

7 

Podgorelec V, Kokol P, Stiglic B and Rozman I: Decision trees: An overview and their use in medicine. J Med Syst. 26:445–463. 2002.PubMed/NCBI View Article : Google Scholar

8 

Yang JD and Roberts LR: Hepatocellular carcinoma: A global view. Nat Rev Gastroenterol Hepatol. 7:448–458. 2010.PubMed/NCBI View Article : Google Scholar

9 

Imamura H, Matsuyama Y, Tanaka E, Ohkubo T, Hasegawa K, Miyagawa S, Sugawara Y, Minagawa M, Takayama T, Kawasaki S and Makuuchi M: Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy. J Hepatol. 38:200–207. 2003.PubMed/NCBI View Article : Google Scholar

10 

Poon RT, Fan ST, Ng IO, Lo CM, Liu CL and Wong J: Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma. Cancer. 89:500–507. 2000.PubMed/NCBI

11 

de Lope CR, Tremosini S, Forner A, Reig M and Bruix J: Management of HCC. J Hepatol. 56 (Suppl 1):S75–S87. 2012.PubMed/NCBI View Article : Google Scholar

12 

Liang JD, Ping XO, Tseng YJ, Huang GT, Lai F and Yang PM: Recurrence predictive emodels for patients with hepatocellular carcinoma after radio frequency ablation using support vector machines with feature selection methods. Comput Methods Programs Biomed. 117:425–434. 2014.PubMed/NCBI View Article : Google Scholar

13 

Divya R and Radha P: An Optimized HCC recurrence prediction using APO algorithm multiple time series clinical liver cancer dataset. J Med Syst. 22(193)2019.PubMed/NCBI View Article : Google Scholar

14 

Xu D, Sheng JQ, Hu PJ, Huang TS and Lee WC: Predicting hepatocellular carcinoma recurrences: A data-driven multiclass classification method incorporating latent variables. J Biomed Inform. 96(103237)2019.PubMed/NCBI View Article : Google Scholar

15 

Maheswari S and Pitchai R: Heart disease prediction system using decision tree and naive bayes algorithm. Curr Med Imaging Rev. 15:712–717. 2019.PubMed/NCBI View Article : Google Scholar

16 

Takada M, Sugimoto M, Naito Y, Moon HG, Han W, Noh DY, Kondo M, Kuroi K, Sasano H, Inamoto T, et al: Prediction of axillary lymph node metastasis in primary breast cancer patients using a decision tree-based model. BMC Med Inform Decis Mak. 12(54)2012.PubMed/NCBI View Article : Google Scholar

17 

Horiguchi K, Toi M, Horiguchi S, Sugimoto M, Naito Y, Hayashi Y, Ueno T, Ohno S, Funata N, Kuroi K, et al: Predictive value of CD24 and CD44 for neoadjuvant chemotherapy response and prognosis in primary breast cancer patients. J Med Dent Sci. 57:165–175. 2010.PubMed/NCBI

18 

Wang ZX, Jiang CP, Cao Y, Zhang G, Chen WB and Ding YT: Preoperative serum liver enzyme markers for predicting early recurrence after curative resection of hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int. 14:178–185. 2015.PubMed/NCBI View Article : Google Scholar

19 

Tovuu LO, Imura S, Utsunomiya T, Morine Y, Ikemoto T, Arakawa Y, Mori H, Hanaoka J, Kanamoto M, Sugimoto K, et al: Role of CD44 expression in non-tumor tissue on intrahepatic recurrence of hepatocellular carcinoma. Int J Clin Oncol. 18:651–656. 2013.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Iwahashi S, Ghaibeh A, Shimada M, Morine Y, Imura S, Ikemoto T, Saito Y and Hirose J: Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method. Mol Clin Oncol 13: 46, 2020.
APA
Iwahashi, S., Ghaibeh, A., Shimada, M., Morine, Y., Imura, S., Ikemoto, T. ... Hirose, J. (2020). Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method. Molecular and Clinical Oncology, 13, 46. https://doi.org/10.3892/mco.2020.2116
MLA
Iwahashi, S., Ghaibeh, A., Shimada, M., Morine, Y., Imura, S., Ikemoto, T., Saito, Y., Hirose, J."Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method". Molecular and Clinical Oncology 13.5 (2020): 46.
Chicago
Iwahashi, S., Ghaibeh, A., Shimada, M., Morine, Y., Imura, S., Ikemoto, T., Saito, Y., Hirose, J."Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method". Molecular and Clinical Oncology 13, no. 5 (2020): 46. https://doi.org/10.3892/mco.2020.2116
Copy and paste a formatted citation
x
Spandidos Publications style
Iwahashi S, Ghaibeh A, Shimada M, Morine Y, Imura S, Ikemoto T, Saito Y and Hirose J: Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method. Mol Clin Oncol 13: 46, 2020.
APA
Iwahashi, S., Ghaibeh, A., Shimada, M., Morine, Y., Imura, S., Ikemoto, T. ... Hirose, J. (2020). Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method. Molecular and Clinical Oncology, 13, 46. https://doi.org/10.3892/mco.2020.2116
MLA
Iwahashi, S., Ghaibeh, A., Shimada, M., Morine, Y., Imura, S., Ikemoto, T., Saito, Y., Hirose, J."Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method". Molecular and Clinical Oncology 13.5 (2020): 46.
Chicago
Iwahashi, S., Ghaibeh, A., Shimada, M., Morine, Y., Imura, S., Ikemoto, T., Saito, Y., Hirose, J."Predictability of postoperative recurrence on hepatocellular carcinoma through data mining method". Molecular and Clinical Oncology 13, no. 5 (2020): 46. https://doi.org/10.3892/mco.2020.2116
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