Dendritic fibromyxolipoma: A case report

Liu,Hongyun; Hei,Shumin; Wang,Jigang; Zhang,Qiliang; Yu,Xinjuan; Chen,Hua

doi:10.3892/mco.2020.2169

Dendritic fibromyxolipoma: A case report

Authors:
- Hongyun Liu
- Shumin Hei
- Jigang Wang
- Qiliang Zhang
- Xinjuan Yu
- Hua Chen
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Affiliations: Department of Pathology, Qingdao Municipal Hospital, Qingdao, Shandong 266071, P.R. China, Department of Pathology, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R. China, Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China, Department of Sports Medicine, Qingdao Municipal Hospital, Qingdao, Shandong 266071, P.R. China, Department of Central Laboratories, Qingdao Municipal Hospital, Qingdao, Shandong 266071, P.R. China
Published online on: November 12, 2020 https://doi.org/10.3892/mco.2020.2169
Article Number: 7
Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Dendritic fibromyxolipoma (DFML) is a rare variant of spindle cell lipoma. It is characterized by extensive myxoid change and the presence of stellate cells with dendritic processes. The present study reports three cases of DFML that arose from the limbs and thoracic cavity. Pathologically, the tumor was composed of mature adipocytes admixing with patch spindle cells in a myxoid stroma. The cell atypia was not apparent and mitotic figures were rare. Immunohistochemistry revealed that the spindle cells were strongly positive for CD34. The three patients demonstrated no significant issues during a two‑year's follow‑up without evidence of recurrence and metastasis. The current study additionally reviewed all reported DFML cases in the PubMed database and Chinese journals.

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1	Suster S, Fisher C and Moran CA: Dendritic fibromyxolipoma: Clinicopathologic study of a distinctive benign soft tissue lesion that may be mistaken for a sarcoma. Ann Diagn Pathol. 2:111–120. 1998.PubMed/NCBI View Article : Google Scholar
2	Wong YP, Chia WK, Low SF, Mohamed-Haflah NH and Sharifah NA: Dendritic fibromyxolipoma: A variant of spindle cell lipoma with extensive myxoid change, with cytogenetic evidence. Pathol Int. 64:346–351. 2014.PubMed/NCBI View Article : Google Scholar
3	Tan GM and Wen P: Clinicopathologic features of dendritic fibromyxolipoma. Zhonghua Bing Li Xue Za Zhi. 32:404–408. 2003.PubMed/NCBI(In Chinese).
4	Karim RZ, McCarthy SW, Palmer AA, Bonar SF and Scolyer RA: Intramuscular dendritic fibromyxolipoma: Myxoid variant of spindle cell lipoma? Pathol Int. 53:252–258. 2003.PubMed/NCBI View Article : Google Scholar
5	Al-Maskery AY, Al-Sidairy SM and Al-Hamadani AS: Dendritic myxofibrolipoma: Often misdiagnosed as sarcoma. Craniomaxillofac Trauma Reconstr. 4:171–174. 2011.PubMed/NCBI View Article : Google Scholar
6	Dahlin LB and Ljungberg O: Dendritic fibromyxolipoma adherent to the median nerve in the forearm. J Plast Surg Hand Surg. 46:120–123. 2012.PubMed/NCBI View Article : Google Scholar
7	Qiao HG, Zhang C, Zhuang YL and Wang J: Dendritic fibromyxolipoma: A clinicopathological analysis of 10 cases. J Clin Exp Pathol. 28:1332–1335. 2012.
8	Zhang XJ, Zhou S, Nie K, Chen DF, Kui GJ and Zhang XH: Dendritic fibromyxolipoma in the right inguinal and perineum regions: A case report and review of the literature. Diagn Pathol. 8(157)2013.PubMed/NCBI View Article : Google Scholar
9	Han XC, Zheng LQ and Shang XL: Dendritic fibromyxolipoma on the nasal tip in an old patient. Int J Clin Exp Pathol. 7:7064–7067. 2014.PubMed/NCBI
10	Yuan XX, Yuan JP, Yang YH, Yin YB and Luo B: CliIlicopathological characteristics of dendritic fibromyxolipoma in muscIe: An anaIysis of 3 cases. J Diagn Pathol. 21(1)2014.
11	Xu X, Xiong W, Zheng L and Yu J: Intramuscular dendritic fibromyxolipoma in a 24-year-old male: A case report and review of the literature. Oncol Lett. 9:583–586. 2015.PubMed/NCBI View Article : Google Scholar
12	Liu S, Wang X, Lei B, Ma H, Li J, Guo D and Xu S: Dendritic fibromyxolipoma in the latissimus dorsi: A case report and review of the literature. Int J Clin Exp Pathol. 8:8650–8654. 2015.PubMed/NCBI
13	Guo WW, Huang WQ, Kong QN and Han ZL: Clinicopathologic analysis of dendritic fibromyxolipoma. J Clin Pathol Res. 35:622–626. 2015.
14	Song L, Wang Z, Xu JW and Qin YJ: Dendritic fibromyxolipoma of jaw: Report of a case. Zhonghua Bing Li Xue Za Zhi. 45:276–277. 2016.PubMed/NCBI View Article : Google Scholar : (In Chinese).
15	Ciloglu S, Duran A, Keskin E and Yigit A: Dendritic fibromyxolipoma of left inguinal region. Indian J Pathol Microbiol. 59:250–251. 2016.PubMed/NCBI View Article : Google Scholar
16	AlAbdulsalam A and Arafah M: Dendritic fibromyxolipoma of the pyriform sinus: A case report and review of the literature. Case Rep Pathol. 2016(7289017)2016.PubMed/NCBI View Article : Google Scholar
17	Xiao XW, Zhang LF, Li WS and Liu Y: Clinicopathological characteristics of dendritic fibromyxolipoma in abdominal cavity: An analysis of two cases. Diagn Pathol. 24(7)2017.
18	Li YQ, Ma Q, Chen Y, Tang Y and Qian ZH: Dendritic fibromyxolipoma: A clinicopathologic analysis of 6 cases and review of the literature. J Clin Pathol Res. 37:527–530. 2017.
19	Ruiz Molina I, Solis Garcia E and Civico Amat V: Dendritic infraclavicular fibromyxolipoma: At the boundary between spindle cell lipoma and solitary fibrous tumour. Rev Esp Patol. 51:44–48. 2018.PubMed/NCBI View Article : Google Scholar : (In Spanish).
20	Fu WL, Tang XF and Guo QN: A Clinicopathologic study of dendritic fibromyxolipoma. Med J West China. 30:503–506. 2018.
21	Abaricia S and Hirbe AC: Diagnosis and treatment of myxoid liposarcomas: Histology matters. Curr Treat Options Oncol. 19(64)2018.PubMed/NCBI View Article : Google Scholar
22	Hei SM, Wei HJ, Chen H and Wang JG: Pathological significance of NY-ESO-1 expression in the diagnosis of myxoid liposarcoma. Zhonghua Bing Li Xue Za Zhi. 48:225–230. 2019.PubMed/NCBI View Article : Google Scholar : (In Chinese).
23	Yu JS, Colborne S, Hughes CS, Morin GB and Nielsen TO: The FUS-DDIT3 interactome in myxoid liposarcoma. Neoplasia. 21:740–751. 2019.PubMed/NCBI View Article : Google Scholar