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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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June-2021 Volume 14 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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Case Report

Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report

  • Authors:
    • Omar Badran
    • Anton Ouryvaev
    • Veronika Baturov
    • Ayelet Shai
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Galilee Medical Centre, Nahariya 22100, Israel, Department of Radiology, Galilee Medical Centre, Nahariya 22100, Israel
  • Article Number: 120
    |
    Published online on: April 14, 2021
       https://doi.org/10.3892/mco.2021.2282
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Abstract

A 63‑year‑old man was hospitalized for immune check‑point inhibitors (ICIs) medicated pneumonitis, secondary to treatment with pembrolizumab for non‑small cell lung cancer. He was treated with high dose steroids, mycophenolate mofetil, empiric broad spectrum antibiotics and empiric trimethoprim‑sulfamethoxazole and intravenous immunoglobulin. Despite the aforementioned treatment, his condition continued to deteriorate. The patient was admitted to the intensive care unit. While intubated, he underwent bronchoscopy and lavage, which was analyzed for potential infectious agents. Cytomegalovirus (CMV) pneumonia was diagnosed and treated. He passed away despite antiviral treatment and maximal supportive care. CMV infection should be suspected in patients failing to recover from toxicities of ICIs with appropriate immunosuppression.
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Copy and paste a formatted citation
Spandidos Publications style
Badran O, Ouryvaev A, Baturov V and Shai A: Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report. Mol Clin Oncol 14: 120, 2021.
APA
Badran, O., Ouryvaev, A., Baturov, V., & Shai, A. (2021). Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report. Molecular and Clinical Oncology, 14, 120. https://doi.org/10.3892/mco.2021.2282
MLA
Badran, O., Ouryvaev, A., Baturov, V., Shai, A."Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report". Molecular and Clinical Oncology 14.6 (2021): 120.
Chicago
Badran, O., Ouryvaev, A., Baturov, V., Shai, A."Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report". Molecular and Clinical Oncology 14, no. 6 (2021): 120. https://doi.org/10.3892/mco.2021.2282
Copy and paste a formatted citation
x
Spandidos Publications style
Badran O, Ouryvaev A, Baturov V and Shai A: Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report. Mol Clin Oncol 14: 120, 2021.
APA
Badran, O., Ouryvaev, A., Baturov, V., & Shai, A. (2021). Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report. Molecular and Clinical Oncology, 14, 120. https://doi.org/10.3892/mco.2021.2282
MLA
Badran, O., Ouryvaev, A., Baturov, V., Shai, A."Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report". Molecular and Clinical Oncology 14.6 (2021): 120.
Chicago
Badran, O., Ouryvaev, A., Baturov, V., Shai, A."Cytomegalovirus pneumonia complicating immune checkpoint inhibitors‑induced pneumonitis: A case report". Molecular and Clinical Oncology 14, no. 6 (2021): 120. https://doi.org/10.3892/mco.2021.2282
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