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A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry

  • Authors:
    • Xiaojun Du
    • Haojun Li
    • Langbo Liu
    • Min Zhang
    • Zhongben Tang
    • Jian Zhang
    • Peng Lin
    • Hong Xie
    • Cheng Chen
  • View Affiliations / Copyright

    Affiliations: Department of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China, Department of Radiology, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, P.R. China, Department of Thoracic Surgery, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563099, P.R. China
    Copyright: © Du et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 124
    |
    Published online on: April 22, 2021
       https://doi.org/10.3892/mco.2021.2286
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Abstract

The present study aimed to investigate the changes in early postoperative lung volume in patients with non‑small cell lung cancer (NSCLC) following video‑assisted thoracic surgery (VATS) and to analyze the effects of the clinical characteristics on the lung volume of the patients. Therefore, 38 patients with NSCLC, who planned to undergo VATS at the Department of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University in June 2019, were enrolled into the present study. The clinical and computed tomography (CT) scan data from the patients was prospectively collected within 1 week preoperatively, and at 1, 3 and 6 months following surgery, then subsequently analyzed. A total of 34 patients successfully completed follow‑up and were included in the datasets. The results showed that the volume of the right lung was larger compared with that in the left one, at each observational time point. The whole, right and left lung held the same trendline of volume changes, which was sharply decreased during the first postoperative month, increased quickly over the next 3 months, and slowly increased from months 3 to 6. There were 7 patients, whose whole lung volume was increased at 6 months following surgery compared with that preoperatively. In addition, significant differences were observed between males and females in the whole, right and left lung volume. However, the differences on the postoperative net expansion volume of the whole lung were not significant among sex, age, body mass index (BMI), smoking status and surgical side subgroups. The early changes of the postoperative lung volume were not linear, since the lung volume was significantly reduced during the first postoperative month, quickly increased in the next 3 months, and slowly increased from months 3 to 6. Sex, age, BMI, smoking status and surgical sides was not found to affect the postoperative volume and net expansion of the whole lung following VATS lobectomy.
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Copy and paste a formatted citation
Spandidos Publications style
Du X, Li H, Liu L, Zhang M, Tang Z, Zhang J, Lin P, Xie H and Chen C: A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry. Mol Clin Oncol 14: 124, 2021.
APA
Du, X., Li, H., Liu, L., Zhang, M., Tang, Z., Zhang, J. ... Chen, C. (2021). A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry. Molecular and Clinical Oncology, 14, 124. https://doi.org/10.3892/mco.2021.2286
MLA
Du, X., Li, H., Liu, L., Zhang, M., Tang, Z., Zhang, J., Lin, P., Xie, H., Chen, C."A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry". Molecular and Clinical Oncology 14.6 (2021): 124.
Chicago
Du, X., Li, H., Liu, L., Zhang, M., Tang, Z., Zhang, J., Lin, P., Xie, H., Chen, C."A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry". Molecular and Clinical Oncology 14, no. 6 (2021): 124. https://doi.org/10.3892/mco.2021.2286
Copy and paste a formatted citation
x
Spandidos Publications style
Du X, Li H, Liu L, Zhang M, Tang Z, Zhang J, Lin P, Xie H and Chen C: A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry. Mol Clin Oncol 14: 124, 2021.
APA
Du, X., Li, H., Liu, L., Zhang, M., Tang, Z., Zhang, J. ... Chen, C. (2021). A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry. Molecular and Clinical Oncology, 14, 124. https://doi.org/10.3892/mco.2021.2286
MLA
Du, X., Li, H., Liu, L., Zhang, M., Tang, Z., Zhang, J., Lin, P., Xie, H., Chen, C."A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry". Molecular and Clinical Oncology 14.6 (2021): 124.
Chicago
Du, X., Li, H., Liu, L., Zhang, M., Tang, Z., Zhang, J., Lin, P., Xie, H., Chen, C."A preliminary study identifies early postoperative lung volume changes in patients with non‑small cell lung cancer following video‑assisted thoracic surgery using CT volumetry". Molecular and Clinical Oncology 14, no. 6 (2021): 124. https://doi.org/10.3892/mco.2021.2286
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