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Molecular and Clinical Oncology
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Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission

  • Authors:
    • Toshiki Terao
    • Junichiro Yuda
    • Nobuhiko Yamauchi
    • Yong-Mei Guo
    • Kaoru Shimada
    • Masato Sugano
    • Genichiro Ishii
    • Yosuke Minami
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, National Cancer Center Hospital East, Kashiwa, Chiba 277‑8577, Japan, Department of Radiology, National Cancer Center Hospital East, Kashiwa, Chiba 277‑8577, Japan, Department of Pathology, National Cancer Center Hospital East, Kashiwa, Chiba 277‑8577, Japan
    Copyright: © Terao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 125
    |
    Published online on: April 23, 2021
       https://doi.org/10.3892/mco.2021.2287
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Abstract

Gray zone lymphoma (GZL) is a rare type of B‑cell lymphoma characterized by features of both diffuse large B‑cell lymphoma and classical Hodgkin lymphoma (cHL). The prognosis of GZL is poorer than that of cHL and mediastinal large B‑cell lymphoma. However, an optimal treatment strategy for relapsed/refractory (R/R) GZL has not been established in the clinical setting. The current study reported an excellent clinical response in a patient with R/R CD30‑positive GZL who received brentuximab vedotin (BV) maintenance after autologous stem cell transplantation (ASCT). Although the patient was resistant to prior treatments, BV maintenance after ASCT achieved long‑term remission. Hence, BV was determined to be a safe and effective therapeutic option for CD30‑positive R/R GZL.
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Copy and paste a formatted citation
Spandidos Publications style
Terao T, Yuda J, Yamauchi N, Guo Y, Shimada K, Sugano M, Ishii G and Minami Y: Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission. Mol Clin Oncol 14: 125, 2021.
APA
Terao, T., Yuda, J., Yamauchi, N., Guo, Y., Shimada, K., Sugano, M. ... Minami, Y. (2021). Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission. Molecular and Clinical Oncology, 14, 125. https://doi.org/10.3892/mco.2021.2287
MLA
Terao, T., Yuda, J., Yamauchi, N., Guo, Y., Shimada, K., Sugano, M., Ishii, G., Minami, Y."Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission". Molecular and Clinical Oncology 14.6 (2021): 125.
Chicago
Terao, T., Yuda, J., Yamauchi, N., Guo, Y., Shimada, K., Sugano, M., Ishii, G., Minami, Y."Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission". Molecular and Clinical Oncology 14, no. 6 (2021): 125. https://doi.org/10.3892/mco.2021.2287
Copy and paste a formatted citation
x
Spandidos Publications style
Terao T, Yuda J, Yamauchi N, Guo Y, Shimada K, Sugano M, Ishii G and Minami Y: Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission. Mol Clin Oncol 14: 125, 2021.
APA
Terao, T., Yuda, J., Yamauchi, N., Guo, Y., Shimada, K., Sugano, M. ... Minami, Y. (2021). Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission. Molecular and Clinical Oncology, 14, 125. https://doi.org/10.3892/mco.2021.2287
MLA
Terao, T., Yuda, J., Yamauchi, N., Guo, Y., Shimada, K., Sugano, M., Ishii, G., Minami, Y."Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission". Molecular and Clinical Oncology 14.6 (2021): 125.
Chicago
Terao, T., Yuda, J., Yamauchi, N., Guo, Y., Shimada, K., Sugano, M., Ishii, G., Minami, Y."Brentuximab vedotin maintenance after autologous stem cell transplantation for refractory gray zone lymphoma with long‑term remission". Molecular and Clinical Oncology 14, no. 6 (2021): 125. https://doi.org/10.3892/mco.2021.2287
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