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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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December-2021 Volume 15 Issue 6

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Case Report Open Access

Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report

  • Authors:
    • Masako Ishikawa
    • Kentaro Nakayama
    • Hitomi Yamashita
    • Tomoka Ishibashi
    • Seiya Sato
    • Sonomi Kurose
    • Kiyoka Sawada
    • Hiroki Sasamori
    • Sultana Razia
    • Noriyoshi Ishikawa
    • Satoru Kyo
  • View Affiliations / Copyright

    Affiliations: Department of Obstetrics and Gynecology, Shimane University Faculty of Medicine, Izumo, Shimane 6938501, Japan, Department of Organ Pathology, Shimane University Faculty of Medicine, Izumo, Shimane 6938501, Japan
    Copyright: © Ishikawa et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 250
    |
    Published online on: October 8, 2021
       https://doi.org/10.3892/mco.2021.2412
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Abstract

The treatment of cervical intraepithelial neoplasia (CIN) can result in under‑ or overtreatment. The current report describes a case of undertreatment of a cervical tumor. A 72‑year‑old woman was preoperatively diagnosed with CIN3. Following surgery, the final diagnosis of the excised specimen was keratinizing squamous cell carcinoma that measured 2.5 cm in size. The exocervical margin and deep margin were negative. The patient received adjuvant therapy with concurrent chemoradiotherapy and never had disease recurrence. In elderly patients, making an accurate preoperative diagnosis based on specimens from cervical biopsies with or without colposcopy is difficult. MRI may be an accurate preoperative indicator of early cervical tumor, although some studies have demonstrated that MRI has a limitation with respect to its diagnostic ability. Other studies have reported that it is necessary to perform conization prior to hysterectomy. Physicians must reconsider the determined preoperative diagnosis of an early cervical tumor and establish standard guidelines for deciding when to use surgical treatment in elderly patients.
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Copy and paste a formatted citation
Spandidos Publications style
Ishikawa M, Nakayama K, Yamashita H, Ishibashi T, Sato S, Kurose S, Sawada K, Sasamori H, Razia S, Ishikawa N, Ishikawa N, et al: Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report. Mol Clin Oncol 15: 250, 2021.
APA
Ishikawa, M., Nakayama, K., Yamashita, H., Ishibashi, T., Sato, S., Kurose, S. ... Kyo, S. (2021). Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report. Molecular and Clinical Oncology, 15, 250. https://doi.org/10.3892/mco.2021.2412
MLA
Ishikawa, M., Nakayama, K., Yamashita, H., Ishibashi, T., Sato, S., Kurose, S., Sawada, K., Sasamori, H., Razia, S., Ishikawa, N., Kyo, S."Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report". Molecular and Clinical Oncology 15.6 (2021): 250.
Chicago
Ishikawa, M., Nakayama, K., Yamashita, H., Ishibashi, T., Sato, S., Kurose, S., Sawada, K., Sasamori, H., Razia, S., Ishikawa, N., Kyo, S."Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report". Molecular and Clinical Oncology 15, no. 6 (2021): 250. https://doi.org/10.3892/mco.2021.2412
Copy and paste a formatted citation
x
Spandidos Publications style
Ishikawa M, Nakayama K, Yamashita H, Ishibashi T, Sato S, Kurose S, Sawada K, Sasamori H, Razia S, Ishikawa N, Ishikawa N, et al: Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report. Mol Clin Oncol 15: 250, 2021.
APA
Ishikawa, M., Nakayama, K., Yamashita, H., Ishibashi, T., Sato, S., Kurose, S. ... Kyo, S. (2021). Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report. Molecular and Clinical Oncology, 15, 250. https://doi.org/10.3892/mco.2021.2412
MLA
Ishikawa, M., Nakayama, K., Yamashita, H., Ishibashi, T., Sato, S., Kurose, S., Sawada, K., Sasamori, H., Razia, S., Ishikawa, N., Kyo, S."Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report". Molecular and Clinical Oncology 15.6 (2021): 250.
Chicago
Ishikawa, M., Nakayama, K., Yamashita, H., Ishibashi, T., Sato, S., Kurose, S., Sawada, K., Sasamori, H., Razia, S., Ishikawa, N., Kyo, S."Underdiagnosis of early cervical cancer with an invisible cervical transformation zone in an elderly patient: A case report". Molecular and Clinical Oncology 15, no. 6 (2021): 250. https://doi.org/10.3892/mco.2021.2412
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