Transvaginal lymphatic embolization of the fistula between a pelvic lymphocele and the vaginal stump following radical hysterectomy and sentinel pelvic lymph node biopsy in a patient with cervical cancer: A case report

Lee,Yeon Jee; Lee,In Joon; Park,Sohyun; Kim,Tae-Sung; Lim,Myong Cheol

doi:10.3892/mco.2021.2482

February-2022 Volume 16 Issue 2

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February-2022 Volume 16 Issue 2

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Case Report Open Access

Transvaginal lymphatic embolization of the fistula between a pelvic lymphocele and the vaginal stump following radical hysterectomy and sentinel pelvic lymph node biopsy in a patient with cervical cancer: A case report

Authors:
- Yeon Jee Lee
- In Joon Lee
- Sohyun Park
- Tae-Sung Kim
- Myong Cheol Lim
View Affiliations / Copyright

Affiliations: Center for Gynecologic Cancer, Research Institute and Hospital, National Cancer Center, Goyang‑si, Gyeonggi‑do 10408, Republic of Korea, Department of Radiology, National Cancer Center, Goyang‑si, Gyeonggi‑do 10408, Republic of Korea, Department of Nuclear Medicine, National Cancer Center, Goyang‑si, Gyeonggi‑do 10408, Republic of Korea

Copyright: © Lee et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 49
|
Published online on: December 24, 2021

https://doi.org/10.3892/mco.2021.2482
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Abstract

A lymphocele is a common complication that occurs following pelvic lymph node dissection. However, the complication of lymphoceles following sentinel pelvic lymph node biopsy has not been previously reported, to the best of our knowledge. A 49‑year‑old female patient had undergone radical hysterectomy and pelvic lymph node biopsy for stage IB1 cervical cancer 5 months previously and presented with a profuse watery vaginal discharge of ~2 liters per day. A fistula connecting the lymphocele and the vaginal stump was identified using lymphoscintigraphy and single photon emission CT/CT. Transvaginal lymphatic embolization was successfully performed through the vaginal fistulous tract, resulting in immediate reduction of the vaginal discharge. In conclusion, the case of fistula formation between pelvic lymphocele and vaginal stump was encountered at our department and was reported with a literature review. To the best of our knowledge, there are no previous reports on lymphoceles with direct communication to the vaginal mucosa, particularly following sentinel pelvic lymph node biopsy. The present study reported the case of a patient who was successfully treated for a pelvic lymphocele with direct communication to the vaginal mucosa.

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1	Mattiuzzi C and Lippi G: Cancer statistics: A comparison between World health organization (WHO) and global burden of disease (GBD). Eur J Public Health. 30:1026–1027. 2020.PubMed/NCBI View Article : Google Scholar
2	Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68:394–424. 2018.PubMed/NCBI View Article : Google Scholar
3	Weinberger V, Cibula D and Zikan M: Lymphocele: Prevalence and management in gynecological malignancies. Expert Rev Anticancer Ther. 14:307–317. 2014.PubMed/NCBI View Article : Google Scholar
4	Karcaaltincaba M and Akhan O: Radiologic imaging and percutaneous treatment of pelvic lymphocele. Eur J Radiol. 55:340–354. 2005.PubMed/NCBI View Article : Google Scholar
5	Cheong YC, Bajekal N and Li TC: Peritoneal closure-to close or not to close. Hum Reprod. 16:1548–1552. 2001.PubMed/NCBI View Article : Google Scholar
6	Kadanali S, Erten O and Kucukozkan T: Pelvic and periaortic pertioneal closure or non-closure at lymphadenectomy in ovarian cancer: Effects on morbidity and adhesion formation. Eur J Surg Oncol. 22:282–285. 1996.PubMed/NCBI View Article : Google Scholar
7	Ai W, Liang Z, Li F and Yu H: Internal hernia beneath superior vesical artery after pelvic lymphadenectomy for cervical cancer: A case report and literature review. BMC Surg. 20(312)2020.PubMed/NCBI View Article : Google Scholar
8	Clarke-Pearson DL, Synan IS and Creasman WT: Significant venous thromboembolism caused by pelvic lymphocysts: Diagnosis and management. Gynecol Oncol. 13:136–143. 1982.PubMed/NCBI View Article : Google Scholar
9	Cibula D and McCluggage WG: Sentinel lymph node (SLN) concept in cervical cancer: Current limitations and unanswered questions. Gynecol Oncol. 152:202–207. 2019.PubMed/NCBI View Article : Google Scholar
10	Kim JH, Kim DY, Suh DS, Kim JH, Kim YM, Kim YT and Nam JH: The efficacy of sentinel lymph node mapping with indocyanine green in cervical cancer. World J Surg Oncol. 16(52)2018.PubMed/NCBI View Article : Google Scholar
11	Abu-Rustum NR, Yashar CM, Bean S, Bradley K, Campos SM, Chon HS, Chu C, Cohn D, Crispens MA, Damast S, et al: NCCN guidelines insights: Cervical cancer, version 1.2020. J Natl Compr Canc Netw. 18:660–666. 2020.PubMed/NCBI View Article : Google Scholar
12	vanSonnenberg E, Wittich GR, Casola G, Wing VW, Halasz NA, Lee AS and Withers C: Lymphoceles: Imaging characteristics and percutaneous management. Radiology. 161:593–596. 1986.PubMed/NCBI View Article : Google Scholar
13	Aronowitz J and Kaplan AL: The management of a pelvic lymphocele by the use of a percutaneous indwelling catheter inserted with ultrasound guidance. Gynecol Oncol. 16:292–295. 1993.PubMed/NCBI View Article : Google Scholar
14	Kim JK, Jeong YY, Kim YH, Kim YC, Kang HK and Choi HS: Postoperative pelvic lymphocele: Treatment with simple percutaneous catheter drainage. Radiology. 212:390–394. 1999.PubMed/NCBI View Article : Google Scholar
15	Chu HH, Shin JH, Kim JW, Noh SY, Yang WJ and Park S: Lymphangiography and lymphatic embolization for the management of pelvic lymphocele after radical prostatectomy in prostatic cancer. Cardiovasc Intervent Radiol. 42:873–879. 2019.PubMed/NCBI View Article : Google Scholar
16	Lee EW, Shin JH, Ko HK, Park J, Kim SH and Sung KB: Lymphangiography to treat postoperative lymphatic leakage: A technical review. Korean J Radiol. 15:724–732. 2014.PubMed/NCBI View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Transvaginal lymphatic embolization of the fistula between a pelvic lymphocele and the vaginal stump following radical hysterectomy and sentinel pelvic lymph node biopsy in a patient with cervical cancer: A case report

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