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Molecular and Clinical Oncology
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Print ISSN: 2049-9450 Online ISSN: 2049-9469
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October-2023 Volume 19 Issue 4

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The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review

  • Authors:
    • Kaname Sakuma
    • Tomoyuki Kii
    • Toko Machida
    • Nobukazu Fuwa
    • Akira Tanaka
  • View Affiliations / Copyright

    Affiliations: Department of Oral and Maxillofacial Surgery, The Nippon Dental University School of Life Dentistry at Niigata, Niigata 951‑8580, Japan, Department of Radiation Oncology, Central Japan International Medical Center, Minokamo, Gifu 505‑8510, Japan
    Copyright: © Sakuma et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 76
    |
    Published online on: August 10, 2023
       https://doi.org/10.3892/mco.2023.2672
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Abstract

Superselective intra‑arterial chemoradiotherapy (SSIACRT) is one of the curative treatments for advanced oral cancer. SSIACRT can reportedly treat cervical lymph node metastases in the level I‑IIA area by super selectively catheterizing the facial artery (FA) and infusing drugs. However, since advanced oral cancer lesions involve a number of feeding vessels, retrograde treatment requires the placement of catheters from the superficial temporal artery (STA) and occipital artery (OA). Furthermore, in the case of level IIB lymph node metastasis, the catheter must be changed because it is necessary to administer anticancer drugs to more than three routes, including the OA, when the feeding arteries of the primary tumor are combined. The external carotid artery sheath (ECAS) system used in the present study involves the insertion of a microcatheter or steering catheter from one route of the STA, allowing selection of numerous feeding vessels, including the OA. The ECAS system can facilitate the administration of chemotherapy via the STA simultaneously to the maxillary artery, lingual artery, FA and OA. The present study describes cases of maxillary gingival cancer and tongue cancer with cervical lymph node metastasis, which were treated with the ECAS system via the STA; the treatment successfully controlled both the primary tumor and cervical lymph node metastasis. In the two cases described in the present study, metastatic lymph nodes were found in the level ⅠB and ⅡB region, but were successfully treated by administering cisplatin via the OA, in addition to the primary lesion. To date, to the best of our knowledge, there is no case report clearly referring to the treatment of lymph node metastasis using the ECAS system. In conclusion, SSIACRT using ECAS may be considered a useful treatment for oral cancer with cervical lymph node metastasis.
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Copy and paste a formatted citation
Spandidos Publications style
Sakuma K, Kii T, Machida T, Fuwa N and Tanaka A: The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review. Mol Clin Oncol 19: 76, 2023.
APA
Sakuma, K., Kii, T., Machida, T., Fuwa, N., & Tanaka, A. (2023). The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review. Molecular and Clinical Oncology, 19, 76. https://doi.org/10.3892/mco.2023.2672
MLA
Sakuma, K., Kii, T., Machida, T., Fuwa, N., Tanaka, A."The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review". Molecular and Clinical Oncology 19.4 (2023): 76.
Chicago
Sakuma, K., Kii, T., Machida, T., Fuwa, N., Tanaka, A."The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review". Molecular and Clinical Oncology 19, no. 4 (2023): 76. https://doi.org/10.3892/mco.2023.2672
Copy and paste a formatted citation
x
Spandidos Publications style
Sakuma K, Kii T, Machida T, Fuwa N and Tanaka A: The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review. Mol Clin Oncol 19: 76, 2023.
APA
Sakuma, K., Kii, T., Machida, T., Fuwa, N., & Tanaka, A. (2023). The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review. Molecular and Clinical Oncology, 19, 76. https://doi.org/10.3892/mco.2023.2672
MLA
Sakuma, K., Kii, T., Machida, T., Fuwa, N., Tanaka, A."The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review". Molecular and Clinical Oncology 19.4 (2023): 76.
Chicago
Sakuma, K., Kii, T., Machida, T., Fuwa, N., Tanaka, A."The ECAS system can superselectively administer anticancer drugs to numerous feeding arteries from the superficial temporal artery: A case report and literature review". Molecular and Clinical Oncology 19, no. 4 (2023): 76. https://doi.org/10.3892/mco.2023.2672
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