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Case Report Open Access

Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review

  • Authors:
    • Yuki Denda
    • Yoichi Matsuo
    • Keisuke Nonoyama
    • Hiromichi Murase
    • Tomokatsu Kato
    • Yuichi Hayashi
    • Hiroyuki Imafuji
    • Kenta Saito
    • Mamoru Morimoto
    • Hiroyuki Kato
    • Michihiro Yoshida
    • Itaru Naitoh
    • Kazuki Hayashi
    • Ryo Ogawa
    • Hiroki Takahashi
    • Shuji Takiguchi
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467‑8601, Japan, Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467‑8601, Japan, Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi 467‑8601, Japan
    Copyright: © Denda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 2
    |
    Published online on: November 17, 2023
       https://doi.org/10.3892/mco.2023.2700
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Abstract

The frequency of metastasis to the pancreas is limited, and the frequency of metastasis of a squamous cell carcinoma of the esophagus is limited even further. The curative resection of this type of metastatic lesion has been reported for some patients; however, the survival benefit that can be attributed to these procedures has not yet been clearly determined. The patient examined in the present study was a 54‑year‑old man who was diagnosed with a lower thoracic esophageal cancer. Computed tomography revealed a 2‑cm tumor at the tail of the pancreas. Since no other obvious distal metastases were observed, the patient underwent simultaneous surgical procedures, excising the esophageal squamous cell carcinoma and the pancreatic metastasis. A histopathological examination confirmed squamous cell carcinoma in both specimens. The patient has been free of disease for 9 months since the resection. A literature review of all relevant cases to date also demonstrated that the primary tumor site in all cases of patients with esophageal cancer presenting with metastasis to the pancreas was the lower thoracic esophagus. Complete simultaneous resections of esophageal squamous cell carcinoma and a solitary metastasis to the pancreas is beneficial and may produce favorable outcomes. However, due to the reduced number of corresponding reports, further studies are required for the confirmation of the benefits of surgery.
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1 

Nakagawa S, Kanda T, Kosugi S, Ohashi M, Suzuki T and Hatakeyama K: Recurrence pattern of squamous cell carcinoma of the thoracic esophagus after extended radical esophagectomy with three-field lymphadenectomy. J Am Coll Surg. 198:205–211. 2004.PubMed/NCBI View Article : Google Scholar

2 

Takeuchi M, Takeuchi H, Kawakubo H, Booka E, Mayanagi S, Fukuda K, Nakamura R, Suda K, Wada N and Kitagawa Y: Perioperative risk calculator predicts long-term oncologic outcome for patients with esophageal carcinoma. Ann Surg Oncol. 25:837–843. 2018.PubMed/NCBI View Article : Google Scholar

3 

Shiozaki H, Sudo K, Xiao L, Wadhwa R, Elimova E, Hofstetter WL, Skinner HD, Lee JH, Weston B, Bhutani MS, et al: Distribution and timing of distant metastasis after local therapy in a large cohort of patients with esophageal and esophagogastric junction cancer. Oncology. 86:336–339. 2014.PubMed/NCBI View Article : Google Scholar

4 

Quint LE, Hepburn LM, Francis IR, Whyte RI and Orringer MB: Incidence and distribution of distant metastases from newly diagnosed esophageal carcinoma. Cancer. 76:1120–1125. 1995.PubMed/NCBI View Article : Google Scholar

5 

Sperti C, Pasquali C, Liessi G, Pinciroli L, Decet G and Pedrazzoli S: Pancreatic resection for metastatic tumors to the pancreas. J Surg Oncol. 83:161–166. 2003.PubMed/NCBI View Article : Google Scholar

6 

Adsay NV, Andea A, Basturk O, Kilinc N, Nassar H and Cheng JD: Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchows Arch. 444:527–535. 2004.PubMed/NCBI View Article : Google Scholar

7 

Masetti M, Zanini N, Martuzzi F, Fabbri C, Mastrangelo L, Landolfo G, Fornelli A, Burzi M, Vezzelli E and Jovine E: Analysis of prognostic factors in metastatic tumors of the pancreas: A single-center experience and review of the literature. Pancreas. 39:135–143. 2010.PubMed/NCBI View Article : Google Scholar

8 

Varker KA, Muscarella P, Wall K, Ellison C and Bloomston M: Pancreatectomy for non-pancreatic malignancies results in improved survival after R0 resection. World J Surg Oncol. 5(145)2007.PubMed/NCBI View Article : Google Scholar

9 

Reddy S and Wolfgang CL: The role of surgery in the management of isolated metastases to the pancreas. Lancet Oncol. 10:287–293. 2009.PubMed/NCBI View Article : Google Scholar

10 

Koizumi W, Kitago M, Shinoda M, Yagi H, Abe Y, Oshima G, Hori S, Inomata K, Kawakubo H, Kawaida M and Kitagawa Y: Successful resection of pancreatic metastasis from oesophageal squamous cell carcinoma: a case report and review of the literature. BMC Cancer. 19(320)2019.PubMed/NCBI View Article : Google Scholar

11 

Okamoto H, Hara Y, Chin M, Hagiwara M, Onodera Y, Horii S, Shirahata Y, Kamei T, Hashizume E and Ohuchi N: An extremely rare case of pancreatic metastasis of esophageal squamous cell carcinoma. World J Gastroenterol. 20:593–597. 2014.PubMed/NCBI View Article : Google Scholar

12 

Esfehani MH, Mahmoodzadeh H, Alibakhshi A and Safavi F: Esophageal squamous cell carcinoma with pancreatic metastasis: A case report. Acta Med Iran. 49:760–762. 2011.PubMed/NCBI

13 

Park C, Jang JY, Kim YH, Hwang EJ, Na KY, Kim KY, Park JH and Chang YW: A case of esophageal squamous cell carcinoma with pancreatic metastasis. Clin Endosc. 46:197–200. 2013.PubMed/NCBI View Article : Google Scholar

14 

Brierley JD (eds): TNM Classfication of Malignant Tumours, 8th Edition. Willey-Blackwell, Hoboken, 2016.

15 

Brown HA, Dotto J, Robert M and Salem RR: Squamous cell carcinoma of the pancreas. J Clin Gastroenterol. 39:915–919. 2005.PubMed/NCBI View Article : Google Scholar

16 

Itani KM, Karni A and Green L: Squamous cell carcinoma of the pancreas. J Gastrointest Surg. 3:512–515. 1999.PubMed/NCBI View Article : Google Scholar

17 

Beyer KL, Marshall JB, Metzler MH, Poulter JS, Seger RM and Díaz-Arias AA: Squamous cell carcinoma of the pancreas. Report of an unusual case and review of the literature. Dig Dis Sci. 37:312–318. 1992.PubMed/NCBI View Article : Google Scholar

18 

Sears HF, Kim Y and Strawitz J: Squamous cell carcinoma of the pancreas. J Surg Oncol. 14:261–265. 1980.PubMed/NCBI View Article : Google Scholar

19 

Nakashima H, Hayakawa T, Hoshino M, Kamiya Y, Ohara H, Yamada T, Mizuno K, Inagaki T, Nakazawa T, Yamada H, et al: Squamous cell carcinoma of the pancreas with massive invasion of the retroperitoneum. Intern Med. 34:61–64. 1995.PubMed/NCBI View Article : Google Scholar

20 

Brayko CM and Doll DC: Squamous cell carcinoma of the pancreas associated with hypercalcemia. Gastroenterology. 83:1297–1299. 1982.PubMed/NCBI

21 

Maeno T, Satoh H, Ishikawa H, Yamashita YT, Naito T, Fujiwara M, Kamma H, Ohtsuka M and Hasegawa S: Patterns of pancreatic metastasis from lung cancer. Anticancer Res. 18:2881–2884. 1998.PubMed/NCBI

22 

Yildirim Y and Sanci M: The feasibility and morbidity of distal pancreatectomy in extensive cytoreductive surgery for advanced epithelial ovarian cancer. Arch Gynecol Obstet. 272:31–34. 2005.PubMed/NCBI View Article : Google Scholar

23 

Nagashima K, Irisawa A, Tominaga K, Kashima K, Kunogi Y, Minaguchi T, Izawa N, Yamamiya A, Yamabe A, Hoshi K, et al: The role of endoscopic ultrasound for esophageal varices. Diagnostics (Basel). 10(1007)2020.PubMed/NCBI View Article : Google Scholar

24 

Al-Shehri A, Silverman S and King KM: Squamous cell carcinoma of the pancreas. Curr Oncol. 15:293–297. 2008.PubMed/NCBI View Article : Google Scholar

25 

Ishikawa T, Hirooka Y, Teman CJ, Goto H and Belletrutti PJ: An unusual case of pancreatic metastasis from squamous cell carcinoma of the lung diagnosed by EUS-guided fine needle biopsy. Case Rep Gastrointest Med. 2017(3212056)2017.PubMed/NCBI View Article : Google Scholar

26 

Pannala R, Hallberg-Wallace KM, Smith AL, Nassar A, Zhang J, Zarka M, Reynolds JP and Chen L: Endoscopic ultrasound-guided fine needle aspiration cytology of metastatic renal cell carcinoma to the pancreas: A multi-center experience. Cytojournal. 13(24)2016.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Denda Y, Matsuo Y, Nonoyama K, Murase H, Kato T, Hayashi Y, Imafuji H, Saito K, Morimoto M, Kato H, Kato H, et al: Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review. Mol Clin Oncol 20: 2, 2024.
APA
Denda, Y., Matsuo, Y., Nonoyama, K., Murase, H., Kato, T., Hayashi, Y. ... Takiguchi, S. (2024). Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review. Molecular and Clinical Oncology, 20, 2. https://doi.org/10.3892/mco.2023.2700
MLA
Denda, Y., Matsuo, Y., Nonoyama, K., Murase, H., Kato, T., Hayashi, Y., Imafuji, H., Saito, K., Morimoto, M., Kato, H., Yoshida, M., Naitoh, I., Hayashi, K., Ogawa, R., Takahashi, H., Takiguchi, S."Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review". Molecular and Clinical Oncology 20.1 (2024): 2.
Chicago
Denda, Y., Matsuo, Y., Nonoyama, K., Murase, H., Kato, T., Hayashi, Y., Imafuji, H., Saito, K., Morimoto, M., Kato, H., Yoshida, M., Naitoh, I., Hayashi, K., Ogawa, R., Takahashi, H., Takiguchi, S."Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review". Molecular and Clinical Oncology 20, no. 1 (2024): 2. https://doi.org/10.3892/mco.2023.2700
Copy and paste a formatted citation
x
Spandidos Publications style
Denda Y, Matsuo Y, Nonoyama K, Murase H, Kato T, Hayashi Y, Imafuji H, Saito K, Morimoto M, Kato H, Kato H, et al: Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review. Mol Clin Oncol 20: 2, 2024.
APA
Denda, Y., Matsuo, Y., Nonoyama, K., Murase, H., Kato, T., Hayashi, Y. ... Takiguchi, S. (2024). Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review. Molecular and Clinical Oncology, 20, 2. https://doi.org/10.3892/mco.2023.2700
MLA
Denda, Y., Matsuo, Y., Nonoyama, K., Murase, H., Kato, T., Hayashi, Y., Imafuji, H., Saito, K., Morimoto, M., Kato, H., Yoshida, M., Naitoh, I., Hayashi, K., Ogawa, R., Takahashi, H., Takiguchi, S."Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review". Molecular and Clinical Oncology 20.1 (2024): 2.
Chicago
Denda, Y., Matsuo, Y., Nonoyama, K., Murase, H., Kato, T., Hayashi, Y., Imafuji, H., Saito, K., Morimoto, M., Kato, H., Yoshida, M., Naitoh, I., Hayashi, K., Ogawa, R., Takahashi, H., Takiguchi, S."Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review". Molecular and Clinical Oncology 20, no. 1 (2024): 2. https://doi.org/10.3892/mco.2023.2700
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