|
1
|
Sung H, Ferlay J, Siegel RL, Laversanne M,
Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020:
GLOBOCAN estimates of incidence and mortality worldwide for 36
cancers in 185 countries. CA Cancer J Clin. 71:209–249.
2021.PubMed/NCBI View Article : Google Scholar
|
|
2
|
Mittelstadt S, Kelemen O, Admard J,
Gschwind A, Koch A, Wörz S, Oberlechner E, Engler T, Bonzheim I,
Staebler A, et al: Detection of circulating cell-free HPV DNA of 13
HPV types for patients with cervical cancer as potential biomarker
to monitor therapy response and to detect relapse. Br J Cancer.
128:2097–2103. 2023.PubMed/NCBI View Article : Google Scholar
|
|
3
|
Zhou L, Qiu Q, Zhou Q, Li J, Yu M, Li K,
Xu L, Ke X, Xu H, Lu B, et al: Long-read sequencing unveils
high-resolution HPV integration and its oncogenic progression in
cervical cancer. Nat Commun. 13(2563)2022.PubMed/NCBI View Article : Google Scholar
|
|
4
|
Carneiro BA, Elvin JA, Kamath SD, Ali SM,
Paintal AS, Restrepo A, Berry E, Giles FJ and Johnson ML:
FGFR3-TACC3: A novel gene fusion in cervical cancer. Gynecol Oncol
Rep. 13:53–56. 2015.PubMed/NCBI View Article : Google Scholar
|
|
5
|
Amatu A, Sartore-Bianchi A, Bencardino K,
Pizzutilo EG, Tosi F and Siena S: Tropomyosin receptor kinase (TRK)
biology and the role of NTRK gene fusions in cancer. Ann Oncol. 30
(Suppl 8):viii5–viii15. 2019.PubMed/NCBI View Article : Google Scholar
|
|
6
|
Westphalen CB, Krebs MG, Le Tourneau C,
Sokol ES, Maund SL, Wilson TR, Jin DX, Newberg JY, Fabrizio D,
Veronese L, et al: Genomic context of NTRK1/2/3 fusion-positive
tumours from a large real-world population. NPJ Precis Oncol.
5(69)2021.PubMed/NCBI View Article : Google Scholar
|
|
7
|
Somwar R, Hofmann NE, Smith B, Odintsov I,
Vojnic M, Linkov I, Tam A, Khodos I, Mattar MS, de Stanchina E, et
al: NTRK kinase domain mutations in cancer variably impact
sensitivity to type I and type II inhibitors. Commun Biol.
3(776)2020.PubMed/NCBI View Article : Google Scholar
|
|
8
|
Gambella A, Senetta R, Collemi G, Vallero
SG, Monticelli M, Cofano F, Zeppa P, Garbossa D, Pellerino A, Rudà
R, et al: NTRK fusions in central nervous system tumors: A rare,
but worthy target. Int J Mol Sci. 21(753)2020.PubMed/NCBI View Article : Google Scholar
|
|
9
|
Lemmon MA and Schlessinger J: Cell
signaling by receptor tyrosine kinases. Cell. 141:1117–1134.
2010.PubMed/NCBI View Article : Google Scholar
|
|
10
|
Amatu A, Sartore-Bianchi A and Siena S:
NTRK gene fusions as novel targets of cancer therapy across
multiple tumour types. ESMO Open. 1(e000023)2016.PubMed/NCBI View Article : Google Scholar
|
|
11
|
Ardini E, Bosotti R, Borgia AL, De Ponti
C, Somaschini A, Cammarota R, Amboldi N, Raddrizzani L, Milani A,
Magnaghi P, et al: The TPM3-NTRK1 rearrangement is a recurring
event in colorectal carcinoma and is associated with tumor
sensitivity to TRKA kinase inhibition. Mol Oncol. 8:1495–1507.
2014.PubMed/NCBI View Article : Google Scholar
|
|
12
|
Vaishnavi A, Le AT and Doebele RC: TRKing
down an old oncogene in a new era of targeted therapy. Cancer
Discov. 5:25–34. 2015.PubMed/NCBI View Article : Google Scholar
|
|
13
|
Deinhardt K and Chao MV: Trk receptors.
Handb Exp Pharmacol. 220:103–119. 2014.PubMed/NCBI View Article : Google Scholar
|
|
14
|
Cocco E, Scaltriti M and Drilon A: NTRK
fusion-positive cancers and TRK inhibitor therapy. Nat Rev Clin
Oncol. 15:731–747. 2018.PubMed/NCBI View Article : Google Scholar
|
|
15
|
Hechtman JF: NTRK insights: Best practices
for pathologists. Mod Pathol. 35:298–305. 2022.PubMed/NCBI View Article : Google Scholar
|
|
16
|
Ranzi V, Meakin SO, Miranda C, Mondellini
P, Pierotti MA and Greco A: The signaling adapters fibroblast
growth factor receptor substrate 2 and 3 are activated by the
thyroid TRK oncoproteins. Endocrinology. 144:922–928.
2003.PubMed/NCBI View Article : Google Scholar
|
|
17
|
Drilon A, Nagasubramanian R, Blake JF, Ku
N, Tuch BB, Ebata K, Smith S, Lauriault V, Kolakowski GR,
Brandhuber BJ, et al: A next-generation TRK kinase inhibitor
overcomes acquired resistance to prior TRK kinase inhibition in
patients with TRK fusion-positive solid tumors. Cancer Discov.
7:963–972. 2017.PubMed/NCBI View Article : Google Scholar
|
|
18
|
Rasi Bonab F, Baghbanzadeh A, Ghaseminia
M, Bolandi N, Mokhtarzadeh A, Amini M, Dadashzadeh K,
Hajiasgharzadeh K, Baradaran B and Bannazadeh Baghi H: Molecular
pathways in the development of HPV-induced cervical cancer. EXCLI
J. 20:320–337. 2021.PubMed/NCBI View Article : Google Scholar
|
|
19
|
Skinner SR, Wheeler CM, Romanowski B,
Castellsagué X, Lazcano-Ponce E, Del Rosario-Raymundo MR, Vallejos
C, Minkina G, Pereira Da Silva D, McNeil S, et al: Progression of
HPV infection to detectable cervical lesions or clearance in adult
women: Analysis of the control arm of the VIVIANE study. Int J
Cancer. 138:2428–2438. 2016.PubMed/NCBI View Article : Google Scholar
|
|
20
|
Ronco G, Dillner J, Elfström KM, Tunesi S,
Snijders PJ, Arbyn M, Kitchener H, Segnan N, Gilham C, Giorgi-Rossi
P, et al: Efficacy of HPV-based screening for prevention of
invasive cervical cancer: Follow-up of four European randomised
controlled trials. Lancet. 383:524–532. 2014.PubMed/NCBI View Article : Google Scholar
|
|
21
|
Haręża DA, Wilczyński JR and Paradowska E:
Human papillomaviruses as infectious agents in gynecological
cancers. Oncogenic properties of viral proteins. Int J Mol Sci.
23(1818)2022.PubMed/NCBI View Article : Google Scholar
|
|
22
|
Chan CK, Aimagambetova G, Ukybassova T,
Kongrtay K and Azizan A: Human papillomavirus infection and
cervical cancer: epidemiology, screening, and vaccination-review of
current perspectives. J Oncol. 2019(3257939)2019.PubMed/NCBI View Article : Google Scholar
|
|
23
|
Zhang L, Wu J, Ling MT, Zhao L and Zhao
KN: The role of the PI3K/Akt/mTOR signalling pathway in human
cancers induced by infection with human papillomaviruses. Mol
Cancer. 14(87)2015.PubMed/NCBI View Article : Google Scholar
|
|
24
|
Komatsu N, Aoki K, Yamada M, Yukinaga H,
Fujita Y, Kamioka Y and Matsuda M: Development of an optimized
backbone of FRET biosensors for kinases and GTPases. Mol Biol Cell.
22:4647–4656. 2011.PubMed/NCBI View Article : Google Scholar
|
|
25
|
Bossler F, Hoppe-Seyler K and Hoppe-Seyler
F: PI3K/AKT/mTOR signaling regulates the virus/host cell crosstalk
in HPV-positive cervical cancer cells. Int J Mol Sci.
20(2188)2019.PubMed/NCBI View Article : Google Scholar
|
|
26
|
Boyle W, Williams A, Sundar S, Yap J,
Taniere P, Rehal P and Ganesan R: TMP3-NTRK1 rearranged uterine
sarcoma: A case report. Case Rep Womens Health.
28(e00246)2020.PubMed/NCBI View Article : Google Scholar
|
|
27
|
Chiang S, Cotzia P, Hyman DM, Drilon A,
Tap WD, Zhang L, Hechtman JF, Frosina D, Jungbluth AA, Murali R, et
al: NTRK fusions define a novel uterine sarcoma subtype with
features of fibrosarcoma. Am J Surg Pathol. 42:791–798.
2018.PubMed/NCBI View Article : Google Scholar
|
|
28
|
Costigan DC, Nucci MR, Dickson BC, Chang
MC, Song S, Sholl LM, Hornick JL, Fletcher CDM and Kolin DL:
NTRK-rearranged uterine sarcomas: Clinicopathologic features of 15
cases, literature review, and risk stratification. Am J Surg
Pathol. 46:1415–1429. 2022.PubMed/NCBI View Article : Google Scholar
|
|
29
|
Bühler MM, Honcharova-Biletska H, Pauli C,
Chronas D and Bolten K: Conservative surgical treatment with
fertility preservation in a young adult with NTRK rearranged
spindle cell neoplasm of the uterine cervix. Gynecol Oncol Rep.
48(101233)2023.PubMed/NCBI View Article : Google Scholar
|
|
30
|
Wells AE, Mallen AM, Bui MM, Reed DR and
Apte SM: NTRK-1 fusion in endocervical fibroblastic malignant
peripheral nerve sheath tumor marking eligibility for larotrectinib
therapy: A case report. Gynecol Oncol Rep. 28:141–144.
2019.PubMed/NCBI View Article : Google Scholar
|
|
31
|
Croce S, Hostein I, Longacre TA, Mills AM,
Pérot G, Devouassoux-Shisheboran M, Velasco V, Floquet A, Guyon F,
Chakiba C, et al: Uterine and vaginal sarcomas resembling
fibrosarcoma: A clinicopathological and molecular analysis of 13
cases showing common NTRK-rearrangements and the description of a
COL1A1-PDGFB fusion novel to uterine neoplasms. Mod Pathol.
32:1008–1022. 2019.PubMed/NCBI View Article : Google Scholar
|
|
32
|
Dang X, Xiang T, Zhao C, Tang H and Cui P:
EML4-NTRK3 fusion cervical sarcoma: A case report and literature
review. Front Med (Lausanne). 9(832376)2022.PubMed/NCBI View Article : Google Scholar
|
|
33
|
Devereaux KA, Weiel JJ, Mills AM, Kunder
CA and Longacre TA: Neurofibrosarcoma revisited: An institutional
case series of uterine sarcomas harboring kinase-related fusions
with report of a novel FGFR1-TACC1 fusion. Am J Surg Pathol.
45:638–652. 2021.PubMed/NCBI View Article : Google Scholar
|
|
34
|
Fang X, Huang R and Zhang Z:
NTRK-rearranged uterine sarcoma: A case report. Asian J Surg.
46:4764–4765. 2023.PubMed/NCBI View Article : Google Scholar
|
|
35
|
Gatalica Z, Xiu J, Swensen J and Vranic S:
Molecular characterization of cancers with NTRK gene fusions. Mod
Pathol. 32:147–153. 2019.PubMed/NCBI View Article : Google Scholar
|
|
36
|
Goulding EA, Morreau P, De Silva M, Watson
M, van Vliet C, Leung B and Eva LJ: Case report: NTRK1-rearranged
cervical sarcoma with fibrosarcoma like morphology presenting in a
13-year-old managed with a neo-adjuvant TRK-inhibitor and surgical
excision. Gynecol Oncol Rep. 37(100845)2021.PubMed/NCBI View Article : Google Scholar
|
|
37
|
Xiaoqing Z, Shan Z, Zhansan S, Xianyang Z,
Xiaoyan C and Qiong Z: The clinicopathological analysis of cervical
NTRK-rearranged spindle cell tumor. Mod Oncol. 31:2069–2072.
2023.
|
|
38
|
Wong DD, Vargas AC, Bonar F, Maclean F,
Kattampallil J, Stewart C, Sulaiman B, Santos L and Gill AJ:
NTRK-rearranged mesenchymal tumours: Diagnostic challenges,
morphological patterns and proposed testing algorithm. Pathology.
52:401–409. 2020.PubMed/NCBI View Article : Google Scholar
|
|
39
|
Tsai JW, Lee JC, Hsieh TH, Huang SC, Lee
PH, Liu TT, Kao YC, Chang CD, Weng TF, Li CF, et al: Adult
NTRK-rearranged spindle cell neoplasms of the viscera: With an
emphasis on rare locations and heterologous elements. Mod Pathol.
35:911–921. 2022.PubMed/NCBI View Article : Google Scholar
|
|
40
|
Takahashi A, Kurosawa M, Uemura M,
Kitazawa J and Hayashi Y: Anaplastic lymphoma kinase-negative
uterine inflammatory myofibroblastic tumor containing the
ETV6-NTRK3 fusion gene: A case report. J Int Med Res. 46:3498–3503.
2018.PubMed/NCBI View Article : Google Scholar
|
|
41
|
Rabban JT, Devine WP, Sangoi AR, Poder L,
Alvarez E, Davis JL, Rudzinski E, Garg K and Bean GR: NTRK fusion
cervical sarcoma: a report of three cases, emphasising
morphological and immunohistochemical distinction from other
uterine sarcomas, including adenosarcoma. Histopathology.
77:100–111. 2020.PubMed/NCBI View Article : Google Scholar
|
|
42
|
Nilforoushan N, Wethington SL, Nonogaki H,
Gross J, Vang R and Xing D: NTRK-fusion sarcoma of the uterine
cervix: Report of 2 cases with comparative clinicopathologic
features. Int J Gynecol Pathol. 41:642–648. 2022.PubMed/NCBI View Article : Google Scholar
|
|
43
|
Munkhdelger J, Shimooka T, Koyama Y, Ikeda
S, Mikami Y, Fukuoka J, Hori T and Bychkov A: Basaloid squamous
cell carcinoma of the uterine cervix: Report of a case with
molecular analysis. Int J Surg Pathol. 29:770–774. 2021.PubMed/NCBI View Article : Google Scholar
|
|
44
|
Moh M, Johnson CM, Geurts JL and Bishop
EE: Uterine sarcoma with a novel WWOX-NTRK2 fusion in a
postmenopausal woman with li-fraumeni-like syndrome: A case that
expands the spectrum of NTRK-rearranged uterine tumors. AJSP Rev
Rep. 26:304–306. 2021.
|
|
45
|
Hanhan L: Clinicopathological analysis of
one case of cervical sarcoma with NTRK gene rearrangement. J Clin
Exp Pathol. 37:1240–1243. 2021.
|
|
46
|
Xiaoqi L: Case reports of NTRK-rearranged
cervical sarcomas and literature review. Anti-Tumor Pharm.
13:515–520. 2023.
|
|
47
|
Hodgson A, Pun C, Djordjevic B and
Turashvili G: NTRK-rearranged cervical sarcoma: Expanding the
clinicopathologic spectrum. Int J Gynecol Pathol. 40:73–77.
2021.PubMed/NCBI View Article : Google Scholar
|
|
48
|
Hartmaier RJ, Albacker LA, Chmielecki J,
Bailey M, He J, Goldberg ME, Ramkissoon S, Suh J, Elvin JA,
Chiacchia S, et al: High-throughput genomic profiling of adult
solid tumors reveals novel insights into cancer pathogenesis.
Cancer Res. 77:2464–2475. 2017.PubMed/NCBI View Article : Google Scholar
|
