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Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province

  • Authors:
    • Lucia Mangone
    • Francesco Marinelli
    • Isabella Bisceglia
    • Francesca Roncaglia
    • Valentina Mastrofilippo
    • Fortunato Morabito
    • Antonino Neri
    • Lorenzo Aguzzoli
    • Vincenzo Dario Mandato
  • View Affiliations / Copyright

    Affiliations: Epidemiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, I‑42122 Reggio Emilia, Italy, Unit of Obstetrics and Gynaecology, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, I‑42122 Reggio Emilia, Italy, Biotechnology Research Unit, AO di Cosenza, I‑87051 Aprigliano, Italy, Scientific Directorate, Azienda Unità Sanitaria Locale‑IRCCS di Reggio Emilia, I‑42122 Reggio Emilia, Italy
    Copyright: © Mangone et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 71
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    Published online on: August 2, 2024
       https://doi.org/10.3892/mco.2024.2770
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Abstract

While cervical cancer is relatively uncommon in Western countries, it continues to pose significant concern due to its high mortality rates. Intraepithelial forms [cervical intraepithelial neoplasia (CIN) 2 and CIN 3] are more prevalent in regions with comprehensive screening coverage, particularly in areas that use the Papanicolaou test and HPV detection. The present study aims to characterize the trends of precancerous lesions and infiltrating tumors over a decade, assessing survival rates by age, stage and country of origin. A total of 1,752 CIN 2/3 lesions and 152 infiltrating cancers were recorded in the Reggio Emilia Cancer Registry between January 2008 and December 2018. A clear increase in CIN 2/3 lesions was observed over the years while infiltrating tumors remained rare and the numbers of cancer cases declined. The 5‑year survival rate was found to be 67%, with survival closely correlated with stage (88, 82, 74 and 12% for stages I, II, III and IV, respectively) and age (84, 80 and 37% for ages <40, 40‑65 and 65+, respectively). Multivariable analysis confirmed an excess risk for advanced stages III (HR 3.1; 95% CI, 1.3‑7.3) and IV (HR 19.6; 95% CI, 8.2‑46.7), as well as in women 65+ (HR 2.8; 95% CI, 1.0‑8.1). Analysis of national origins revealed comparable stage distribution for Italians and non‑Italians at stage I (41 vs. 47%), while a notable disparity emerged for stage IV (28 vs. 6%). This difference could be attributed to the average age of Italians compared to non‑­Italians (59 vs. 49 years). Overall, the present study underscored the importance of continued surveillance and intervention strategies targeting advanced‑stage disease, particularly in older populations and among non‑Italian patients. Efforts to enhance screening coverage and access to timely interventions remain critical in reducing the burden of cervical cancer and improving survival outcomes.
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1 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 71:209–249. 2021.PubMed/NCBI View Article : Google Scholar

2 

AIOM AIRTUM, SIAPEC-IAP: I Cancer numbers in Italy, Intermedia editore, September 2020.

3 

Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, Snijders PJ, Peto J, Meijer CJ and Muñoz N: Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 189:12–19. 1999.PubMed/NCBI View Article : Google Scholar

4 

Thun M, Linet MS, Cerhan JR, Haiman CA and Schottenfeld D: Cancer Epidemiology and Prevention. 4th edition. Oxford University Press, pp925-946, 2018.

5 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 71:209–249. 2021.PubMed/NCBI View Article : Google Scholar

6 

Loopik DL, IntHout J, Ebisch RMF, Melchers WJG, Massuger LFAG, Siebers AG and Bekkers RLM: The risk of cervical cancer after cervical intraepithelial neoplasia grade 3: A population-based cohort study with 80,442 women. Gynecol Oncol. 157:195–201. 2020.PubMed/NCBI View Article : Google Scholar

7 

Global HPV Vaccine Introduction Overview: Projected and current national introductions, demonstration/pilot projects, gender-neutral vaccination programs, and global HPV vaccine introduction maps (2006-2023). PATH, 2020. Available from: path.org/resources/global-hpv-vaccine-introduction-overview/.

8 

World Health Organization (WHO): ‘Best buys’ and other recommended interventions for the prevention and control of non-communicable diseases: Updated Appendix 3 of the Global Action Plan for the Prevention and Control of Non communicable Diseases 2013-2020WHO, 2017. Available from: who.int/ncds/governance/appendix3-update/en/). Accessed on April 2024.

9 

World Health Organization (WHO): WHO guidelines for the use of thermal ablation for cervical pre-cancer lesions. WHO, 2019. Available from: Who.int/reproductivehealth/publications/thermal-ablation-for-cervical-pre-cancer-lesions/en/). Accessed on April 2024.

10 

World Health Organization (WHO): WHO Director-General calls for all countries to take action to help end the suffering caused by cervical cancer. WHO, 2018. Available from: who.int/reproductivehealth/call-to-action-elimination-cervical-cancer/en/). Accessed on April 2024.

11 

Mangone L, Borciani E, Michiara M, Vicentini M, Carrozzi G, Mancuso P, Sacchettini C and Rossi P: Tumors in the provinces of the Vast Northern Emilia Area: Piacenza, Parma, Reggio Emilia and Modena: Years 2013-2014. The Cancer Registries, 2015. https://www.ausl.mo.it/media/interno.pdf?x14278. Accessed on April, 2024.

12 

Fritz A, Percy C, Jack A, Shanmugaratnam K, Sobin L, Parkin DM and Whelan S: International Classification of Disease for Oncology. 3rd edition. World Health Organization, 2013.

13 

Sobin L, Gospodarowicz M and Wittekind C: TNM Classification of Malignant Tumours. 7th edition. UICC, Wiley-Blackwell, Hoboken, NJ, 2010.

14 

ECIS (European Cancer Information System). https://ecis.jrc.ec.europa.eu/ (accessed on April 2024).

15 

Yang M, Du J, Lu H, Xiang F, Mei H and Xiao H: Global trends and age-specific incidence and mortality of cervical cancer from 1990 to 2019: An international comparative study based on the global burden of disease. BMJ Open. 12(e055470)2022.PubMed/NCBI View Article : Google Scholar

16 

Yuan M, Zhao X, Wang H, Hu S and Zhao F: Trend in cervical cancer incidence and mortality rates in China, 2006-2030: A bayesian age-period-cohort modeling study. Cancer Epidemiol Biomarkers Prev. 32:825–833. 2023.PubMed/NCBI View Article : Google Scholar

17 

Sun K, Zheng R, Lei L, Zhang S, Zeng H, Wang S, Li L, Chen R, Han B, Peng J, et al: Trends in incidence rates, mortality rates, and age-period-cohort effects of cervical cancer-China, 2003-2017. China CDC Wkly. 4:1070–1076. 2022.PubMed/NCBI View Article : Google Scholar

18 

Raveinthiranathan N, Simkin J, Donken R, Ogilvie G, Smith L, Van Niekerk D, Lee M and Woods RR: Age-specific trends of invasive cervical cancer incidence in British Columbia, Canada, 1971-2017. Curr Oncol. 30:7692–7705. 2023.PubMed/NCBI View Article : Google Scholar

19 

Kau YC, Liu FC, Kuo CF, Huang HJ, Li AH, Hsieh MY and Yu HP: Trend and survival outcome in Taiwan cervical cancer patients: A population-based study. Medicine (Baltimore). 98(e14848)2019.PubMed/NCBI View Article : Google Scholar

20 

Rossi PG, Marsili LM, Camilloni L, Iossa A, Lattanzi A, Sani C, Di Pierro C, Grazzini G, Angeloni C, Capparucci P, et al: The effect of self-sampled HPV testing on participation to cervical cancer screening in Italy: A randomised controlled trial (ISRCTN96071600). Br J Cancer. 104:248–254. 2011.PubMed/NCBI View Article : Google Scholar

21 

Bogani G, DI Donato V, Sopracordevole F, Ciavattini A, Ghelardi A, Lopez S, Simoncini T, Plotti F, Casarin J, Serati M, et al: Recurrence rate after loop electrosurgical excision procedure (LEEP) and laser Conization: A 5-year follow-up study. Gynecol Oncol. 159:636–641. 2020.PubMed/NCBI View Article : Google Scholar

22 

Giannini A, Di Donato V, Sopracordevole F, Ciavattini A, Ghelardi A, Vizza E, D'Oria O, Simoncini T, Plotti F, Casarin J, et al: Outcomes of high-grade cervical dysplasia with positive margins and HPV persistence after cervical conization. Vaccines (Basel). 11(698)2023.PubMed/NCBI View Article : Google Scholar

23 

Bogani G, Sopracordevole F, Di Donato V, Ciavattini A, Ghelardi A, Lopez S, Simoncini T, Plotti F, Casarin J, Serati M, et al: High-risk HPV-positive and -negative high-grade cervical dysplasia: Analysis of 5-year outcomes. Gynecol Oncol. 161:173–178. 2021.PubMed/NCBI View Article : Google Scholar

24 

Ochs K, Meili G, Diebold J, Arndt V and Günthert A: Incidence trends of cervical cancer and its precancerous lesions in women of Central Switzerland from 2000 until 2014. Front Med (Lausanne). 5(58)2018.PubMed/NCBI View Article : Google Scholar

25 

Sivaranjini K, Oak A, Cheulkar S, Maheshwari A, Mahantshetty U and Dikshit R: Role of education and income on disparities of time-to-treatment initiation and its impact on cervical cancer survival. Indian J Public Health. 67:235–239. 2023.PubMed/NCBI View Article : Google Scholar

26 

Gnade CM, Hill EK, Botkin HE, Hefel AR, Hansen HE, Sheets KA, Mott SL, Hardy-Fairbanks AJ and Stockdale CK: Is the age of cervical cancer diagnosis changing over time? J Gynecol Obstet Hum Reprod. 50(102040)2021.PubMed/NCBI View Article : Google Scholar

27 

Cooley JJP, Maguire FB, Morris CR, Parikh-Patel A, Abrahão R, Chen HA and Keegan THM: Cervical cancer stage at diagnosis and survival among women ≥65 years in california. Cancer Epidemiol Biomarkers Prev. 32:91–97. 2023.PubMed/NCBI View Article : Google Scholar

28 

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 68:394–424. 2018.PubMed/NCBI View Article : Google Scholar

29 

Hull R, Mbele M, Makhafola T, Hicks C, Wang SM, Reis RM, Mehrotra R, Mkhize-Kwitshana Z, Kibiki G, Bates DO and Dlamini Z: Cervical cancer in low and middle-income countries. Oncol Lett. 20:2058–2074. 2020.PubMed/NCBI View Article : Google Scholar

30 

Baasland I, Vie GÅ, Romundstad PR and Lönnberg S: Cervical cancer mortality in Norway according to screening attendance and age. Acta Obstet Gynecol Scand. 101:952–959. 2022.PubMed/NCBI View Article : Google Scholar

31 

Kassa R, Irene Y, Woldetsadik E, Kidane E, Higgins M, Dejene T and Wells J: Survival of women with cervical cancer in East Africa: A systematic review and meta-analysis. J Obstet Gynaecol. 43(2253308)2023.PubMed/NCBI View Article : Google Scholar

32 

Mwaliko E, Itsura P, Keter A, De Bacquer D, Buziba N, Bastiaens H, Jackie A, Obala A, Naanyu V, Gichangi P and Temmerman M: Survival of cervical cancer patients at Moi teaching and referral hospital, Eldoret in Western Kenya. BMC Cancer. 23(1104)2023.PubMed/NCBI View Article : Google Scholar

33 

Quinn BA, Deng X, Colton A, Bandyopadhyay D, Carter JS and Fields EC: Increasing age predicts poor cervical cancer prognosis with subsequent effect on treatment and overall survival. Brachytherapy. 18:29–37. 2019.PubMed/NCBI View Article : Google Scholar

34 

Benitez-Restrepo CC, Arias-Ortiz NE and Arboleda-Ruiz WA: Cervical cancer incidence and patient survival in Manizales, Colombia, 2008-2012. Rev Peru Med Exp Salud Publica. 37:438–445. 2020.PubMed/NCBI View Article : Google Scholar : (In Spanish, English).

35 

Bruni L, Serrano B, Roura E, Alemany L, Cowan M, Herrero R, Poljak M, Murillo R, Broutet N, Riley LM and de Sanjose S: Cervical cancer screening programmes and age-specific coverage estimates for 202 countries and territories worldwide: A review and synthetic analysis. Lancet Glob Health. 10:e1115–e1127. 2022.PubMed/NCBI View Article : Google Scholar

36 

Cohen CM, Wentzensen N, Castle PE, Schiffman M, Zuna R, Arend RC and Clarke MA: Racial and ethnic disparities in cervical cancer incidence, survival, and mortality by histologic subtype. J Clin Oncol. 41:1059–1068. 2023.PubMed/NCBI View Article : Google Scholar

37 

Azerkan F, Zendehdel K, Tillgren P, Faxelid E and Sparén P: Risk of cervical cancer among immigrants by age at immigration and follow-up time in Sweden, from 1968 to 2004. Int J Cancer. 123:2664–2670. 2008.PubMed/NCBI View Article : Google Scholar

38 

Tjioe KC, Miranda-Galvis M, Johnson MS, Agrawal G, Balas EA and Cortes JE: The interaction between social determinants of health and cervical cancer survival: A systematic review. Gynecol Oncol. 181:141–154. 2024.PubMed/NCBI View Article : Google Scholar

39 

Donkers H, Bekkers R and Galaal K: Systematic review on socioeconomic deprivation and cervical cancer: Inequalities in survival. J Health Care Poor Underserved. 32:751–766. 2021.PubMed/NCBI View Article : Google Scholar

40 

Hung P, Zahnd WE, Brandt HM, Adams SA, Wang S and Eberth JM: Cervical cancer treatment initiation and survival: The role of residential proximity to cancer care. Gynecol Oncol. 160:219–226. 2021.PubMed/NCBI View Article : Google Scholar

41 

Liu G, Yang Z and Wang D: A Bayesian network predicting survival of cervical cancer patients-Based on surveillance, epidemiology, and end results. Cancer Sci. 114:1131–1141. 2023.PubMed/NCBI View Article : Google Scholar

42 

Wang C, Lester B, Huang L, Sun S and Ko JJ: Patient, disease, and survival outcomes for stage IB to stage IV cervical cancer-A population study. Womens Health (Lond). 19(17455057231164551)2023.PubMed/NCBI View Article : Google Scholar

43 

Presidente del Consiglio dei Ministri: Decreto del Presidente del Consiglio dei Ministri, 3/3/2017,41 Identificazione dei sistemi di sorveglianza e dei registri di mortalità, di tumori e di altre patologie. 17A03142, GU Serie Generale n.109 del (12-05-2017). Available from: https://www.gazzettaufficiale.it/eli/id/2017/05/12/17A03142/sg. Accessed on May, 2024.

44 

Cox DR: Regression models and life-tables. Journal of the Royal Statistical Society, Series B. 34:187–220. 1972.

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Copy and paste a formatted citation
Spandidos Publications style
Mangone L, Marinelli F, Bisceglia I, Roncaglia F, Mastrofilippo V, Morabito F, Neri A, Aguzzoli L and Mandato V: Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province. Mol Clin Oncol 21: 71, 2024.
APA
Mangone, L., Marinelli, F., Bisceglia, I., Roncaglia, F., Mastrofilippo, V., Morabito, F. ... Mandato, V. (2024). Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province. Molecular and Clinical Oncology, 21, 71. https://doi.org/10.3892/mco.2024.2770
MLA
Mangone, L., Marinelli, F., Bisceglia, I., Roncaglia, F., Mastrofilippo, V., Morabito, F., Neri, A., Aguzzoli, L., Mandato, V."Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province". Molecular and Clinical Oncology 21.4 (2024): 71.
Chicago
Mangone, L., Marinelli, F., Bisceglia, I., Roncaglia, F., Mastrofilippo, V., Morabito, F., Neri, A., Aguzzoli, L., Mandato, V."Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province". Molecular and Clinical Oncology 21, no. 4 (2024): 71. https://doi.org/10.3892/mco.2024.2770
Copy and paste a formatted citation
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Spandidos Publications style
Mangone L, Marinelli F, Bisceglia I, Roncaglia F, Mastrofilippo V, Morabito F, Neri A, Aguzzoli L and Mandato V: Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province. Mol Clin Oncol 21: 71, 2024.
APA
Mangone, L., Marinelli, F., Bisceglia, I., Roncaglia, F., Mastrofilippo, V., Morabito, F. ... Mandato, V. (2024). Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province. Molecular and Clinical Oncology, 21, 71. https://doi.org/10.3892/mco.2024.2770
MLA
Mangone, L., Marinelli, F., Bisceglia, I., Roncaglia, F., Mastrofilippo, V., Morabito, F., Neri, A., Aguzzoli, L., Mandato, V."Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province". Molecular and Clinical Oncology 21.4 (2024): 71.
Chicago
Mangone, L., Marinelli, F., Bisceglia, I., Roncaglia, F., Mastrofilippo, V., Morabito, F., Neri, A., Aguzzoli, L., Mandato, V."Trends in cervical cancer: A decade‑long analysis of incidence, survival and demographic disparities in a Northern Italian province". Molecular and Clinical Oncology 21, no. 4 (2024): 71. https://doi.org/10.3892/mco.2024.2770
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