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Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review

  • Authors:
    • Yuru Bai
    • Hong Chen
    • Yuanyuan Duanmu
    • Hang Shi
    • Huifang Fu
    • Yanyi Yu
  • View Affiliations / Copyright

    Affiliations: Department of Oncology, Nanjing Jiangning Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu 211100, P.R. China, Department of Radiology, Nanjing Jiangning Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu 211100, P.R. China, Department of Pathology, Nanjing Jiangning Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu 211100, P.R. China, Department of Dermatology, Nanjing Jiangning Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu 211100, P.R. China
    Copyright: © Bai et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 5
    |
    Published online on: November 1, 2024
       https://doi.org/10.3892/mco.2024.2800
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Abstract

Immune checkpoint inhibitors, a class of anticancer drugs, which act via enhancing T cell responses against tumor cells, are associated with immune‑related adverse events. The skin is one of the most commonly affected organs. In the present study, a case of a 78‑year‑old man, who developed systemic eczema dermatitis due to neoadjuvant treatment of locally advanced gastric adenocarcinoma with sintilimab combined with Tigio plus oxaliplatin regimen, was reported. The eczema dermatitis completely subsided after treatment with methylprednisolone. The patient and his family strongly requested surgical intervention. Postoperative pathology revealed a pathological complete response.
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Copy and paste a formatted citation
Spandidos Publications style
Bai Y, Chen H, Duanmu Y, Shi H, Fu H and Yu Y: Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review. Mol Clin Oncol 22: 5, 2025.
APA
Bai, Y., Chen, H., Duanmu, Y., Shi, H., Fu, H., & Yu, Y. (2025). Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review. Molecular and Clinical Oncology, 22, 5. https://doi.org/10.3892/mco.2024.2800
MLA
Bai, Y., Chen, H., Duanmu, Y., Shi, H., Fu, H., Yu, Y."Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review". Molecular and Clinical Oncology 22.1 (2025): 5.
Chicago
Bai, Y., Chen, H., Duanmu, Y., Shi, H., Fu, H., Yu, Y."Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review". Molecular and Clinical Oncology 22, no. 1 (2025): 5. https://doi.org/10.3892/mco.2024.2800
Copy and paste a formatted citation
x
Spandidos Publications style
Bai Y, Chen H, Duanmu Y, Shi H, Fu H and Yu Y: Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review. Mol Clin Oncol 22: 5, 2025.
APA
Bai, Y., Chen, H., Duanmu, Y., Shi, H., Fu, H., & Yu, Y. (2025). Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review. Molecular and Clinical Oncology, 22, 5. https://doi.org/10.3892/mco.2024.2800
MLA
Bai, Y., Chen, H., Duanmu, Y., Shi, H., Fu, H., Yu, Y."Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review". Molecular and Clinical Oncology 22.1 (2025): 5.
Chicago
Bai, Y., Chen, H., Duanmu, Y., Shi, H., Fu, H., Yu, Y."Adverse skin reactions secondary to sintilimab for advanced gastric adenocarcinoma: A case report and literature review". Molecular and Clinical Oncology 22, no. 1 (2025): 5. https://doi.org/10.3892/mco.2024.2800
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