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Article Special Issue Open Access

Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer

This article is part of the special Issue: Progress in Colorectal Cancer Research
  • Authors:
    • Xiajuan Xue
    • Yugang Yang
    • Xiaozhen Xu
    • Mingzhi Cai
    • Huiqun Shen
  • View Affiliations / Copyright

    Affiliations: Department of Colorectal Surgery, Zhangzhou Municipal Hospital Affiliated of Fujian Medical University, Zhangzhou, Fujian 363000, P.R. China, Gynecology Department, Zhangzhou Municipal Hospital Affiliated of Fujian Medical University, Zhangzhou, Fujian 363000, P.R. China, Department of Medical Oncology, Zhangzhou Municipal Hospital Affiliated of Fujian Medical University, Zhangzhou, Fujian 363000, P.R. China
    Copyright: © Xue et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 25
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    Published online on: January 15, 2025
       https://doi.org/10.3892/mco.2025.2820
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Abstract

In recent years, selective lateral lymph node dissection (LLND) has been performed more frequently. The present study aimed to explore the clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis (LPLNM), which may be helpful for pre‑treatment decisions. The present study included 64 patients with rectal cancer and clinically suspected LPLNM who underwent total mesorectal excision (TME) and LLND between February 2019 and April 2024. According to pathological outcomes, the patients were divided into the negative LPLN (n=40) and positive LPLN (n=24) groups. The primary endpoints were the overall pathological LPLNM positivity rate and different clinical characteristics between the two groups. The secondary endpoint was the identification of predictive factors of pathological LPLNM before surgery. Among the 64 patients, 24 (37.5%) had pathologically confirmed LPLNM, and pathological LPLNM was related to initial lymph node size. When initial LPLN size was <7 mm, the pathological LPLNM rate was 10.5%, whereas when LPLN size was between 7 and 10 mm, the rate was 34.6%, and when LPLN size was >10 mm, the rate was 68.4%. Initial LPLN size (≥7.1 mm, P=0.003) and cN stage (N1‑2, P=0.005) were significantly associated with pathological LPLNM. In multivariate analysis of risk factors, initial LPN size (≥7.1 mm; hazard ratio=4.856, 95% confidence interval 1.158‑20.359, P=0.031) was the only independent risk factor for pathological LPLNM. When the cut‑off initial LPLN size was 7.1 mm, the sensitivity and specificity were 87.5 and 52.5%, respectively, and the area under the curve was 0.748 (P=0.0009). When both LPLN size ≥7.1 mm and cN1‑2 were satisfied, the sensitivity was 66.7%, the specificity increased to 77.5%, and the positive and negative predictive values were 64.0 and 79.5%, respectively. In conclusion, initial LPLN size and cN stage were identified as significant clinical characteristics associated with pathological LPLNM. Patients with an initial LPLN size of ≥7.1 mm and with cN1‑2 stage cancer could benefit from TME + LLND surgery.
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1 

Sato H, Maeda K and Maruta M: Prognostic significance of lateral lymph node dissection in node positive low rectal carcinoma. Int J Colorectal Dis. 26:881–889. 2011.PubMed/NCBI View Article : Google Scholar

2 

Ishihara S, Kawai K, Tanaka T, Kiyomatsu T, Hata K, Nozawa H, Morikawa T and Watanabe T: Oncological outcomes of lateral pelvic lymph node metastasis in rectal cancer treated with preoperative chemoradiotherapy. Dis Colon Rectum. 60:469–476. 2017.PubMed/NCBI View Article : Google Scholar

3 

Nagasaki T, Akiyoshi T, Fujimoto Y, Konishi T, Nagayama S, Fukunaga Y and Ueno M: Preoperative chemoradiotherapy might improve the prognosis of patients with locally advanced low rectal cancer and lateral pelvic lymph node metastases. World J Surg. 41:876–883. 2017.PubMed/NCBI View Article : Google Scholar

4 

Sugihara K, Kobayashi H, Kato T, Mori T, Mochizuki H, Kameoka S, Shirouzu K and Muto T: Indication and benefit of pelvic sidewall dissection for rectal cancer. Dis Colon Rectum. 49:1663–1672. 2006.PubMed/NCBI View Article : Google Scholar

5 

Georgiou P, Tan E, Gouvas N, Antoniou A, Brown G, Nicholls RJ and Tekkis P: Extended lymphadenectomy versus conventional surgery for rectal cancer: A meta-analysis. Lancet Oncol. 10:1053–1062. 2009.PubMed/NCBI View Article : Google Scholar

6 

Moriya Y: Treatment of lateral pelvic nodes metastases from rectal cancer: The future prospective. G Chir. 34:245–248. 2013.PubMed/NCBI

7 

Yano H and Moran BJ: The incidence of lateral pelvic side-wall nodal involvement in low rectal cancer may be similar in Japan and the West. Br J Surg. 95:33–49. 2008.PubMed/NCBI View Article : Google Scholar

8 

Kobayashi H, Mochizuki H, Kato T, Mori T, Kameoka S, Shirouzu K and Sugihara K: Outcomes of surgery alone for lower rectal cancer with and without pelvic sidewall dissection. Dis Colon Rectum. 52:567–576. 2009.PubMed/NCBI View Article : Google Scholar

9 

Kim HJ, Choi GS, Park JS, Park SY, Lee HJ, Woo IT and Park IK: Selective lateral pelvic lymph node dissection: A comparative study of the robotic versus laparoscopic approach. Surg Endosc. 32:2466–2473. 2018.PubMed/NCBI View Article : Google Scholar

10 

Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Kinugasa Y, Komori K, Ohue M, Ota M, Akazai Y, Shiozawa M, et al: Mesorectal excision with or without lateral lymph node dissection for clinical stage II/III lower rectal cancer (JCOG0212): A multicenter, randomized controlled, noninferiority trial. Ann Surg. 266:201–207. 2017.PubMed/NCBI View Article : Google Scholar

11 

Kim MJ, Chang GJ, Lim HK, Song MK, Park SC, Sohn DK, Chang HJ, Kim DY, Park JW, Jeong SY and Oh JH: Oncological impact of lateral lymph node dissection after preoperative chemoradiotherapy in patients with rectal cancer. Ann Surg Oncol. 27:3525–3533. 2020.PubMed/NCBI View Article : Google Scholar

12 

Amin MB, Edge SB, Greene FL and Brierley JD: AJCC cancer staging manual, 8th edition. New York: Springer, 2017.

13 

Ogura A, Konishi T, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, Lee IK, Lee HX, Uehara K, Lee P, et al: Neoadjuvant (chemo)radiotherapy with total mesorectal excision only is not sufficient to prevent lateral local recurrence in enlarged nodes: Results of the multicenter lateral node study of patients with low cT3/4 rectal cancer. J Clin Oncol. 37:33–43. 2019.PubMed/NCBI View Article : Google Scholar

14 

Kroon HM, Malakorn S, Dudi-Venkata NN, Bedrikovetski S, Liu J, Kenyon-Smith T, Bednarski BK, Ogura A, van de Velde CJH, Rutten HJT, et al: Local recurrences in western low rectal cancer patients treated with or without lateral lymph node dissection after neoadjuvant (chemo)radiotherapy: An international multi-centre comparative study. Eur J Surg Oncol. 47:2441–2449. 2021.PubMed/NCBI View Article : Google Scholar

15 

Kroon HM, Hoogervorst LA, Hanna-Rivero N, Traeger L, Dudi-Venkata NN, Bedrikovetski S, Kusters M, Chang GJ, Thomas ML and Sammour T: Systematic review and meta-analysis of long-term oncological outcomes of lateral lymph node dissection for metastatic nodes after neoadjuvant chemoradiotherapy in rectal cancer. Eur J Surg Oncol. 48:1475–1482. 2022.PubMed/NCBI View Article : Google Scholar

16 

Yang X, Yang S, Hu T, Gu C, Wei M, Deng X, Wang Z and Zhou Z: What is the role of lateral lymph node dissection in rectal cancer patients with clinically suspected lateral lymph node metastasis after preoperative chemoradiotherapy? A meta-analysis and systematic review. Cancer Med. 9:4477–4489. 2020.PubMed/NCBI View Article : Google Scholar

17 

Oh HK, Kang SB, Lee SM, Lee SY, Ihn MH, Kim DW, Park JH, Kim YH, Lee KH, Kim JS, et al: Neoadjuvant chemoradiotherapy affects the indications for lateral pelvic node dissection in mid/low rectal cancer with clinically suspected lateral node involvement: A multicenter retrospective cohort study. Ann Surg Oncol. 21:2280–2287. 2014.PubMed/NCBI View Article : Google Scholar

18 

Kawai K, Shiratori H, Hata K, Nozawa H, Tanaka T, Nishikawa T, Murono K and Ishihara S: Optimal size criteria for lateral lymph node dissection after neoadjuvant chemoradiotherapy for rectal cancer. Dis Colon Rectum. 64:274–283. 2021.PubMed/NCBI View Article : Google Scholar

19 

Komori K, Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Shiomi A, Ohue M, Ota M, Akazai Y, Shiozawa M, et al: Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage II/III): The analysis of data from the clinical trial (JCOG0212). Eur J Surg Oncol. 45:336–340. 2019.PubMed/NCBI View Article : Google Scholar

20 

Wang P, Zhou S, Zhou H, Liang J and Zhou Z: Evaluating predictive factors for determining the presence of lateral pelvic node metastasis in rectal cancer patients following neoadjuvant chemoradiotherapy. Colorectal Dis. 21:791–796. 2019.PubMed/NCBI View Article : Google Scholar

21 

Bae JH, Song J, Kim JH, Kye BH, Lee IK, Cho HM and Lee YS: Lateral lymph node size and tumor distance from anal verge accurately predict positive lateral pelvic lymph nodes in rectal cancer: A multi-institutional retrospective cohort study. Dis Colon Rectum. 66:785–795. 2023.PubMed/NCBI View Article : Google Scholar

22 

Ogura A, Konishi T, Beets GL, Cunningham C, Garcia-Aguilar J, Iversen H, Toda S, Lee IK, Lee HX, Uehara K, et al: Lateral nodal features on restaging magnetic resonance imaging associated with lateral local recurrence in low rectal cancer after neoadjuvant chemoradiotherapy or radiotherapy. JAMA Surg. 154(e192172)2019.PubMed/NCBI View Article : Google Scholar

23 

Schaap DP, Boogerd LSF, Konishi T, Cunningham C, Ogura A, Garcia-Aguilar J, Beets GL, Suzuki C, Toda S, Lee IK, et al: Rectal cancer lateral lymph nodes: Multicentre study of the impact of obturator and internal iliac nodes on oncological outcomes. Br J Surg. 108:205–213. 2021.PubMed/NCBI View Article : Google Scholar

24 

Chen JN, Liu Z, Wang ZJ, Mei SW, Shen HY, Li J, Pei W, Wang Z, Wang XS, Yu J and Liu Q: Selective lateral lymph node dissection after neoadjuvant chemoradiotherapy in rectal cancer. World J Gastroenterol. 26:2877–2888. 2020.PubMed/NCBI View Article : Google Scholar

25 

Zhou S, Zhang H, Liang J, Fu W, Lou Z, Feng B, Yang Y, Xie Z and Liu Q: Chinese Lateral Node Collaborative Group. Feasibility, indications, and prognostic significance of selective lateral pelvic lymph node dissection after preoperative chemoradiotherapy in middle/low rectal cancer: Results of a multicenter lateral node study in China. Dis Colon Rectum. 67:228–239. 2024.PubMed/NCBI View Article : Google Scholar

26 

Kim MJ, Kim TH, Kim DY, Kim SY, Baek JY, Chang HJ, Park SC, Park JW and Oh JH: Can chemoradiation allow for omission of lateral pelvic node dissection for locally advanced rectal cancer? J Surg Oncol. 111:459–464. 2015.PubMed/NCBI View Article : Google Scholar

27 

Rooney S, Meyer J, Afzal Z, Ashcroft J, Cheow H, De Paepe KN, Powar M, Simillis C, Wheeler J, Davies J and Joshi H: The role of preoperative imaging in the detection of lateral lymph node metastases in rectal cancer: A systematic review and diagnostic test meta-analysis. Dis Colon Rectum. 65:1436–1446. 2022.PubMed/NCBI View Article : Google Scholar

28 

Hoshino N, Murakami K, Hida K, Sakamoto T and Sakai Y: Diagnostic accuracy of magnetic resonance imaging and computed tomography for lateral lymph node metastasis in rectal cancer: A systematic review and meta-analysis. Int J Clin Oncol. 24:46–52. 2019.PubMed/NCBI View Article : Google Scholar

29 

Mizukami Y, Ueda S, Mizumoto A, Sasada T, Okumura R, Kohno S and Takabayashi A: Diffusion-weighted magnetic resonance imaging for detecting lymph node metastasis of rectal cancer. World J Surg. 35:895–899. 2011.PubMed/NCBI View Article : Google Scholar

30 

Laparoscopic Surgery Committee of the Endoscopist Branch in the Chinese Medical Doctor Association (CMDA); Laparoscopic Surgery Committee of Colorectal Cancer Committee of Chinese Medical Doctor Association (CMDA); Colorectal Surgery Group of the Surgery Branch in the Chinese Medical Association (CMA); Chinese Anti-Cancer Association Colorectal Tumor Integrated Rehabilitation Committee; China International Exchange and Promotive Association for Medical and Health Care Colorectal Disease Branch. Chinese expert consensus on the diagnosis and treatment for lateral lymph node metastasis of rectal cancer (2024 edition). Zhonghua Wei Chang Wai Ke Za Zhi. 27:1–14. 2024.PubMed/NCBI View Article : Google Scholar : (In Chinese).

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Copy and paste a formatted citation
Spandidos Publications style
Xue X, Yang Y, Xu X, Cai M and Shen H: Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer. Mol Clin Oncol 22: 25, 2025.
APA
Xue, X., Yang, Y., Xu, X., Cai, M., & Shen, H. (2025). Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer. Molecular and Clinical Oncology, 22, 25. https://doi.org/10.3892/mco.2025.2820
MLA
Xue, X., Yang, Y., Xu, X., Cai, M., Shen, H."Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer". Molecular and Clinical Oncology 22.3 (2025): 25.
Chicago
Xue, X., Yang, Y., Xu, X., Cai, M., Shen, H."Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer". Molecular and Clinical Oncology 22, no. 3 (2025): 25. https://doi.org/10.3892/mco.2025.2820
Copy and paste a formatted citation
x
Spandidos Publications style
Xue X, Yang Y, Xu X, Cai M and Shen H: Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer. Mol Clin Oncol 22: 25, 2025.
APA
Xue, X., Yang, Y., Xu, X., Cai, M., & Shen, H. (2025). Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer. Molecular and Clinical Oncology, 22, 25. https://doi.org/10.3892/mco.2025.2820
MLA
Xue, X., Yang, Y., Xu, X., Cai, M., Shen, H."Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer". Molecular and Clinical Oncology 22.3 (2025): 25.
Chicago
Xue, X., Yang, Y., Xu, X., Cai, M., Shen, H."Clinical characteristics and predictive factors of pathological lateral pelvic lymph node metastasis in patients with rectal cancer". Molecular and Clinical Oncology 22, no. 3 (2025): 25. https://doi.org/10.3892/mco.2025.2820
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