OHVIRA syndrome pre‑operatively diagnosed using vaginoscopy and hysteroscopy: A case report

Mabuchi,Yasushi; Hirayama,Junya; Ota,Nami; Ino,Kazuhiko

doi:10.3892/mi.2021.20

November-December 2021 Volume 1 Issue 5

Full Size Image

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

November-December 2021 Volume 1 Issue 5

Full Size Image

Case Report Open Access

OHVIRA syndrome pre‑operatively diagnosed using vaginoscopy and hysteroscopy: A case report

Authors:
- Yasushi Mabuchi
- Junya Hirayama
- Nami Ota
- Kazuhiko Ino
View Affiliations / Copyright

Affiliations: Department of Obstetrics and Gynecology, Wakayama Medical University, School of Medicine, Wakayama 641 0012, Japan

Copyright: © Mabuchi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 20
|
Published online on: October 26, 2021

https://doi.org/10.3892/mi.2021.20
Expand metrics +

Abstract

Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome is a rare Mullerian duct anomaly. Cases with pelvic inflammatory disease or endometriosis have been reported, which may influence fertility or the quality of life of patients; therefore, an accurate and early diagnosis is essential. The present study reports the case of patient (25‑year‑old female, gravida 0 para 0) with OHVIRA syndrome. Magnetic resonance imaging and a computed tomography scan revealed uterus didelphys and right renal agenesis. An opening was found on the vaginal septum during the menstrual period. Upon diagnostic vaginoscopy and hysteroscopy through the opening, the right vaginal cavity was enclosed, and the right uterine cervix and cavity were normal. The patient was diagnosed with OHVIRA syndrome. Her vaginal septum was surgically removed under direct visualization and the pathological findings of the resected septum revealed a benign squamous epithelium. The post‑operative course was uneventful and restenosis of the vagina was not observed. On the whole, the present study demonstrates that the technique, diagnostic vaginoscopy and hysteroscopy, is minimally invasive and is sufficient for the diagnosis of incomplete vaginal obstruction‑type OHVIRA syndrome.

View Figures

View References

1	Smith NA and Laufer MR: Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome: Management and follow-up. Fertil Steril. 87:918–922. 2007.PubMed/NCBI View Article : Google Scholar
2	Kamio M, Nagata C, Sameshima H, Togami S and Kobayashi H: Obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome with septic shock: A case report. J Obstet Gynaecol Res. 44:1326–1329. 2018.PubMed/NCBI View Article : Google Scholar
3	Candiani GB, Fedele L and Candiani M: Double uterus, blind hemivagina, and ipsilateral renal agenesis: 36 cases and long-term follow-up. Obstet Gynecol. 90:26–32. 1997.PubMed/NCBI View Article : Google Scholar
4	Rock JA and Jones HW Jr: The double uterus associated with an obstructed hemivagina and ipsilateral renal agenesis. Am J Obstet Gynecol. 138:339–342. 1980.PubMed/NCBI View Article : Google Scholar
5	Zurawin RK, Dietrich JE, Heard MJ and Edwards CL: Didelphic uterus and obstructed hemivagina with renal agenesis: Case report and review of the literature. J Pediatr Adolesc Gynecol. 17:137–141. 2004.PubMed/NCBI View Article : Google Scholar
6	Cheng C, Subedi J, Zhang A, Johnson G, Zhao X, Xu D and Guan X: Vaginoscopic incision of oblique vaginal septum in adolescents with OHVIRA syndrome. Sci Rep. 9(20042)2019.PubMed/NCBI View Article : Google Scholar
7	Johary J, Xue M, Xu B, Xu D and Aili A: Use of hysteroscope for vaginoscopy or hysteroscopy in adolescents for the diagnosis and therapeutic management of gynecologic disorders: A systematic review. J Pediatr Adolesc Gynecol. 28:29–37. 2015.PubMed/NCBI View Article : Google Scholar
8	Shih CL, Hung YC, Chen CP, Chien SC and Lin WC: Resectoscopic excision of the vaginal septum in a virgin with uterus didelphys and obstructed unilateral vagina. Taiwan J Obstet Gynecol. 49:109–111. 2010.PubMed/NCBI View Article : Google Scholar

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

OHVIRA syndrome pre‑operatively diagnosed using vaginoscopy and hysteroscopy: A case report

This article is mentioned in:

Abstract

Figure 1

Figure 2

Figure 3

Related Articles