Open Access

Relapse of Graves' disease following SARS‑CoV‑2 infection: A case report and brief literature review

  • Authors:
    • Saeed Rashaad Mohammed
    • Mallika Tripathi
    • Narine Mack
    • Surujpal Teelucksingh
  • View Affiliations

  • Published online on: December 21, 2021     https://doi.org/10.3892/mi.2021.25
  • Article Number: 25
  • Copyright: © Mohammed et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The interaction between severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) and autoimmune thyroid disease is an emerging phenomenon. The present study describes the case of a 28‑year‑old female who experienced a relapse of Graves' disease following SARS‑CoV‑2 infection. She was biochemically euthyroid for 2 years prior to COVID‑19 infection. However, she began experiencing palpitations, increased sweating and tremors of the hands 9 days after being diagnosed with COVID‑19‑related pneumonia. In addition to presenting this case, a comparison is made of this case to similar reports and the possible mechanisms underlying the association between SARS‑CoV‑2 and Graves' disease are discussed. One is a direct result of viral uptake by thyroid cells, while another is a result of the hyperinflammatory ʻcytokine storm’ and its effects on the hypothalamic‑pituitary‑thyroid axis and T‑cell immunity.
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November-December 2021
Volume 1 Issue 5

Print ISSN: 2754-3242
Online ISSN:2754-1304

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Spandidos Publications style
Mohammed SR, Tripathi M, Mack N and Teelucksingh S: Relapse of Graves' disease following SARS‑CoV‑2 infection: A case report and brief literature review. Med Int 1: 25, 2021
APA
Mohammed, S.R., Tripathi, M., Mack, N., & Teelucksingh, S. (2021). Relapse of Graves' disease following SARS‑CoV‑2 infection: A case report and brief literature review. Medicine International, 1, 25. https://doi.org/10.3892/mi.2021.25
MLA
Mohammed, S. R., Tripathi, M., Mack, N., Teelucksingh, S."Relapse of Graves' disease following SARS‑CoV‑2 infection: A case report and brief literature review". Medicine International 1.5 (2021): 25.
Chicago
Mohammed, S. R., Tripathi, M., Mack, N., Teelucksingh, S."Relapse of Graves' disease following SARS‑CoV‑2 infection: A case report and brief literature review". Medicine International 1, no. 5 (2021): 25. https://doi.org/10.3892/mi.2021.25