Fatal adenovirus pneumonia in a 15‑day‑old infant despite extracorporeal life support treatment: A case report

Wang,Huawei; Pan,Tao; Li,Xin; Zhu,Xueping

doi:10.3892/mi.2022.40

Fatal adenovirus pneumonia in a 15‑day‑old infant despite extracorporeal life support treatment: A case report

Authors:
- Huawei Wang
- Tao Pan
- Xin Li
- Xueping Zhu
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Affiliations: Department of Neonatology, Children's Hospital of Soochow University, Suzhou, Jiangsu 215025, P.R. China, Department of Neonatology, Children's Hospital of Soochow University, Suzhou, Jiangsu 215025, P.R. China, Department of Cardiothoracic Surgery, Children's Hospital of Soochow University, Suzhou, Jiangsu 215025, P.R. China
Published online on: April 26, 2022 https://doi.org/10.3892/mi.2022.40
Article Number: 15
Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Infections are one of the most common causes of severe neonatal diseases and the leading cause of neonatal death. Although respiratory viral infections are widespread, they are still not recognized as the predominant causes of neonatal deaths. Adenovirus infection is uncommon during the neonatal period, and it frequently has a fatal outcome. Furthermore, it is difficult to distinguish from other common bacterial and respiratory viral infections. The present study reports the case of a 15‑day‑old newborn who presented with coagulation disorders and hypoxemia in September, 2020. Human adenovirus of species D‑53 (HAdV‑D53) was detected in the blood and sputum. Severe pneumonia rapidly progressed to multiple organ failure syndrome and the patient succumbed to the disease, despite receiving extracorporeal membrane oxygenation.

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