Open Access

Role of pulmonary function testing in inflammatory bowel diseases (Review)

  • Authors:
    • Vasiliki Epameinondas Georgakopoulou
    • Kyriakos Tarantinos
    • Petros Papalexis
    • Demetrios A. Spandidos
    • Christos Damaskos
    • Aikaterini Gkoufa
    • Serafeim Chlapoutakis
    • Pagona Sklapani
    • Nikolaos Trakas
    • Dimitrios Mermigkis
  • View Affiliations

  • Published online on: August 2, 2022     https://doi.org/10.3892/mi.2022.50
  • Article Number: 25
  • Copyright: © Georgakopoulou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Inflammatory bowel disease (IBD) is a term used to describe chronic inflammatory entities of the gastrointestinal system with an unclear etiology. Extra‑intestinal manifestations beyond the involvement of the gastrointestinal tract can also occur. Several studies have investigated the alterations of pulmonary function tests (PFTs) in patients with IBD. To the best of our knowledge, the present review article is the first to summarize all the types of PFTs that have been performed in patients with IBD. Contradictory data exist regarding the association of PFT alterations with disease activity. PFT abnormalities can develop in individuals with IBD who have no clear clinical signs or radiological evidence, suggesting that PFTs may be useful in detecting latent respiratory involvement. The most prevalent finding in the PFTs of adults and children with IBD is an impairment in the diffusing capacity for carbon monoxide, although evidence on the other tests, particularly spirometric values, and their connection with disease activity is inconsistent.
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July-August 2022
Volume 2 Issue 4

Print ISSN: 2754-3242
Online ISSN:2754-1304

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Spandidos Publications style
Georgakopoulou VE, Tarantinos K, Papalexis P, Spandidos DA, Damaskos C, Gkoufa A, Chlapoutakis S, Sklapani P, Trakas N, Mermigkis D, Mermigkis D, et al: Role of pulmonary function testing in inflammatory bowel diseases (Review). Med Int 2: 25, 2022
APA
Georgakopoulou, V.E., Tarantinos, K., Papalexis, P., Spandidos, D.A., Damaskos, C., Gkoufa, A. ... Mermigkis, D. (2022). Role of pulmonary function testing in inflammatory bowel diseases (Review). Medicine International, 2, 25. https://doi.org/10.3892/mi.2022.50
MLA
Georgakopoulou, V. E., Tarantinos, K., Papalexis, P., Spandidos, D. A., Damaskos, C., Gkoufa, A., Chlapoutakis, S., Sklapani, P., Trakas, N., Mermigkis, D."Role of pulmonary function testing in inflammatory bowel diseases (Review)". Medicine International 2.4 (2022): 25.
Chicago
Georgakopoulou, V. E., Tarantinos, K., Papalexis, P., Spandidos, D. A., Damaskos, C., Gkoufa, A., Chlapoutakis, S., Sklapani, P., Trakas, N., Mermigkis, D."Role of pulmonary function testing in inflammatory bowel diseases (Review)". Medicine International 2, no. 4 (2022): 25. https://doi.org/10.3892/mi.2022.50