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Role of pulmonary function testing in inflammatory bowel diseases (Review)

  • Authors:
    • Vasiliki Epameinondas Georgakopoulou
    • Kyriakos Tarantinos
    • Petros Papalexis
    • Demetrios A. Spandidos
    • Christos Damaskos
    • Aikaterini Gkoufa
    • Serafeim Chlapoutakis
    • Pagona Sklapani
    • Nikolaos Trakas
    • Dimitrios Mermigkis
  • View Affiliations / Copyright

    Affiliations: Pulmonology Department, Laiko General Hospital, 11527 Athens, Greece, 1st Pulmonology Department, Sismanogleio Hospital, 15126 Athens, Greece, Unit of Endocrinology, First Department of Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece, Laboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece, Renal Transplantation Unit, Laiko General Hospital, 11527 Athens, Greece, First Department of Internal Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, 11527 Athens, Greece, Department of Thoracic Surgery, Agios Savvas Hospital, 11522 Athens, Greece, Department of Cytology, Mitera Hospital, 15123 Athens, Greece, Department of Biochemistry, Sismanogleio Hospital, 15126 Athens, Greece
    Copyright: © Georgakopoulou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 25
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    Published online on: August 2, 2022
       https://doi.org/10.3892/mi.2022.50
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Abstract

Inflammatory bowel disease (IBD) is a term used to describe chronic inflammatory entities of the gastrointestinal system with an unclear etiology. Extra‑intestinal manifestations beyond the involvement of the gastrointestinal tract can also occur. Several studies have investigated the alterations of pulmonary function tests (PFTs) in patients with IBD. To the best of our knowledge, the present review article is the first to summarize all the types of PFTs that have been performed in patients with IBD. Contradictory data exist regarding the association of PFT alterations with disease activity. PFT abnormalities can develop in individuals with IBD who have no clear clinical signs or radiological evidence, suggesting that PFTs may be useful in detecting latent respiratory involvement. The most prevalent finding in the PFTs of adults and children with IBD is an impairment in the diffusing capacity for carbon monoxide, although evidence on the other tests, particularly spirometric values, and their connection with disease activity is inconsistent.
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Spandidos Publications style
Georgakopoulou VE, Tarantinos K, Papalexis P, Spandidos DA, Damaskos C, Gkoufa A, Chlapoutakis S, Sklapani P, Trakas N, Mermigkis D, Mermigkis D, et al: Role of pulmonary function testing in inflammatory bowel diseases (Review). Med Int 2: 25, 2022.
APA
Georgakopoulou, V.E., Tarantinos, K., Papalexis, P., Spandidos, D.A., Damaskos, C., Gkoufa, A. ... Mermigkis, D. (2022). Role of pulmonary function testing in inflammatory bowel diseases (Review). Medicine International, 2, 25. https://doi.org/10.3892/mi.2022.50
MLA
Georgakopoulou, V. E., Tarantinos, K., Papalexis, P., Spandidos, D. A., Damaskos, C., Gkoufa, A., Chlapoutakis, S., Sklapani, P., Trakas, N., Mermigkis, D."Role of pulmonary function testing in inflammatory bowel diseases (Review)". Medicine International 2.4 (2022): 25.
Chicago
Georgakopoulou, V. E., Tarantinos, K., Papalexis, P., Spandidos, D. A., Damaskos, C., Gkoufa, A., Chlapoutakis, S., Sklapani, P., Trakas, N., Mermigkis, D."Role of pulmonary function testing in inflammatory bowel diseases (Review)". Medicine International 2, no. 4 (2022): 25. https://doi.org/10.3892/mi.2022.50
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Spandidos Publications style
Georgakopoulou VE, Tarantinos K, Papalexis P, Spandidos DA, Damaskos C, Gkoufa A, Chlapoutakis S, Sklapani P, Trakas N, Mermigkis D, Mermigkis D, et al: Role of pulmonary function testing in inflammatory bowel diseases (Review). Med Int 2: 25, 2022.
APA
Georgakopoulou, V.E., Tarantinos, K., Papalexis, P., Spandidos, D.A., Damaskos, C., Gkoufa, A. ... Mermigkis, D. (2022). Role of pulmonary function testing in inflammatory bowel diseases (Review). Medicine International, 2, 25. https://doi.org/10.3892/mi.2022.50
MLA
Georgakopoulou, V. E., Tarantinos, K., Papalexis, P., Spandidos, D. A., Damaskos, C., Gkoufa, A., Chlapoutakis, S., Sklapani, P., Trakas, N., Mermigkis, D."Role of pulmonary function testing in inflammatory bowel diseases (Review)". Medicine International 2.4 (2022): 25.
Chicago
Georgakopoulou, V. E., Tarantinos, K., Papalexis, P., Spandidos, D. A., Damaskos, C., Gkoufa, A., Chlapoutakis, S., Sklapani, P., Trakas, N., Mermigkis, D."Role of pulmonary function testing in inflammatory bowel diseases (Review)". Medicine International 2, no. 4 (2022): 25. https://doi.org/10.3892/mi.2022.50
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