Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature

Salih,Abdulwahid M.; Qaradakhy,Aras J.; Hassan,Shko H.; Abdullah,Ari M.; Dhahir,Hardi Mohammed; Karim,Sanaa O.; Sofi,Hawar A.; Abdalla,Berun A.; Ali,Muhammad Hassan; Kakamad,Fahmi H.

doi:10.3892/mi.2023.109

September-October 2023 Volume 3 Issue 5

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September-October 2023 Volume 3 Issue 5

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Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature

Authors:
- Abdulwahid M. Salih
- Aras J. Qaradakhy
- Shko H. Hassan
- Ari M. Abdullah
- Hardi Mohammed Dhahir
- Sanaa O. Karim
- Hawar A. Sofi
- Berun A. Abdalla
- Muhammad Hassan Ali
- Fahmi H. Kakamad
View Affiliations / Copyright

Affiliations: Department of Scientific Affairs, Smart Health Tower, Sulaimani, Kurdistan 46000, Iraq

Copyright: © Salih et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 49
|
Published online on: September 5, 2023

https://doi.org/10.3892/mi.2023.109
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Abstract

Tuberculosis of the thyroid gland is rare, and tuberculous granulomatous inflammation of the parathyroid glands is even rarer. The present study reports a rare case of primary hyperparathyroidism caused by tuberculous granulomatous inflammation. A 58‑year‑old female patient presented with generalized body pain persisting for 1 year. She had a history of recurrent renal stones (>20 times) and an incidental finding of multinodular goiter involving the parathyroid on neck ultrasound. A blood analysis revealed elevated levels of serum calcium (11.26 mg/dl) and parathyroid hormone (154.7 pg/ml). The patient underwent the resection of the affected left thyroid lobe under general anesthesia. A histopathological examination revealed parathyroid adenoma with caseating granulomatous inflammation involving the adenoma with focal lymphocytic thyroiditis of the left thyroid gland. Although granulomatous parathyroid disease with parathyroid adenoma causing hypercalcemia is an extremely rare event, it can occur. The treatment of choice is surgical resection.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature

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