Surgical treatment of a very rare case of a huge intraligamental leiomyoma of the uterus: A case report and mini‑review of the literature

Thanasa,Anna; Thanasa,Efthymia; Kamaretsos,Evangelos; Grapsidi,Vasiliki; Xydias,Emmanouil; Ziogas,Apostolos; Gerokostas,Evangelos-Ektoras; Antoniou,Ioannis-Rafail; Paraoulakis,Ioannis; Thanasas,Ioannis

doi:10.3892/mi.2023.126

January-February 2024 Volume 4 Issue 1

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January-February 2024 Volume 4 Issue 1

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Case Report Open Access

Surgical treatment of a very rare case of a huge intraligamental leiomyoma of the uterus: A case report and mini‑review of the literature

Authors:
- Anna Thanasa
- Efthymia Thanasa
- Evangelos Kamaretsos
- Vasiliki Grapsidi
- Emmanouil Xydias
- Apostolos Ziogas
- Evangelos-Ektoras Gerokostas
- Ioannis-Rafail Antoniou
- Ioannis Paraoulakis
- Ioannis Thanasas
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Affiliations: Department of Health Sciences, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece, Department of Obstetrics and Gynecology, General Hospital of Trikala, 42100 Trikala, Greece, Department of Obstetrics and Gynecology, EmbryoClinic IVF, 55133 Thessaloniki, Greece, Department of Medicine, University of Thessaly, School of Health Sciences, 41334 Larissa, Greece

Copyright: © Thanasa et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 2
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Published online on: December 1, 2023

https://doi.org/10.3892/mi.2023.126
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Abstract

Intraligamental leiomyomas of the uterus are rare. Extremely rare are the huge intraligamental fibroids (>20 cm), whose pre‑operative diagnosis and surgical management poses a challenge to everyday clinical practice. The present study describes the case of patient who was subjected to surgical treatment for a huge intraligamental leiomyoma of the uterus, which weighed 3,370 g. A 48‑year‑old patient, without menstrual disorders and with a medical history of atypical symptoms from the digestive tract, was referred for a gynecological examination. Upon a physical examination, the abdomen was found to be bloated and distended, with no signs of peritoneal irritation. An intra‑abdominal mass was suspected, the upper margin of which was palpable at about the level of the xiphoid process. The findings of computed tomography and magnetic resonance imaging confirmed the presence of a huge intra‑abdominal mass, which probably originated from the internal genital organs. Following consultation with the patient, surgical treatment with laparotomy was decided. Intraoperatively, a large pedunculated subserosal leiomyoma was found, arising from the right lateral wall of the uterus with retroperitoneal extension within the leaves of broad ligament. Following the resection of the intraligamental leiomyoma, which had significant surgical challenges, a total hysterectomy with bilateral adnexectomy was performed. The post‑operative course was smooth. In addition, in the present study, a brief review of intraligamental leiomyomas of the uterus is presented, emphasizing the significant diagnostic and surgical challenges and potential intraoperative complications that may arise in the management of patients with this condition.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Surgical treatment of a very rare case of a huge intraligamental leiomyoma of the uterus: A case report and mini‑review of the literature

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