Acquired reactive perforating collagenosis combined with MRSA: A case report

Huang,Fuqian; Ren,Weiqi; Wang,Miaomiao; Li,Xiufang; Pan,Min

doi:10.3892/mi.2023.69

January-February 2023 Volume 3 Issue 1

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January-February 2023 Volume 3 Issue 1

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Case Report Open Access

Acquired reactive perforating collagenosis combined with MRSA: A case report

Authors:
- Fuqian Huang
- Weiqi Ren
- Miaomiao Wang
- Xiufang Li
- Min Pan
View Affiliations / Copyright

Affiliations: Department of Dermatology, Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China

Copyright: © Huang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 9
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Published online on: January 26, 2023

https://doi.org/10.3892/mi.2023.69
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Abstract

Acquired reactive perforating collagenosis (ARPC) is a rare chronic skin disease associated with various internal diseases, particularly diabetes and chronic renal failure. The present study describes the case of a patient with ARPC combined with methicillin‑resistant Staphylococcus aureus (MRSA), in an aim to broaden the current understanding of ARPC. A 75‑year‑old female presented with a 5‑year history of pruritus and ulcerative eruptions on the trunk of her body, which became more severe within 1 year. A cutaneous examination revealed a diffuse distribution of erythema and papules, and nodules of various sizes, some of which sagged at the center and had a dark brown crust. A histopathological analysis revealed typical perforations of the collagen fibers. The patient was initially treated with topical corticosteroids and oral antihistamines for skin lesions and pruritus. Medications for glucose control were also administered. Upon the second admission, a combination of antibiotics and acitretin was added. The keratin plug shrank, and the pruritus was relieved. To date, to the best of our knowledge, this is the first reported case of concurrent ARPC and MRSA.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Acquired reactive perforating collagenosis combined with MRSA: A case report

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Abstract

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