Uterine carcinosarcoma with intestinal involvement: A case report and literature review

Laguna-Hernández,Pilar; Mendoza-Moreno,Fernando; Bru-Aparicio,Marta; Alvarado-Hurtado,Ricardo; Soto-Schütte,Sonia; Serrano-Yébenes,Eduardo; Allaoua-Moussaoui,Youssef; Mañes-Jiménez,Felix; Jiménez-Martín,Rubén; Jiménez-Alvarez,Laura; Córdova-Garcia,Diego; Diez-Alonso,Manuel  Mariano; Gutiérrez-Calvo,Alberto

doi:10.3892/mi.2023.75

March-April 2023 Volume 3 Issue 2

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March-April 2023 Volume 3 Issue 2

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Case Report Open Access

Uterine carcinosarcoma with intestinal involvement: A case report and literature review

Authors:
- Pilar Laguna-Hernández
- Fernando Mendoza-Moreno
- Marta Bru-Aparicio
- Ricardo Alvarado-Hurtado
- Sonia Soto-Schütte
- Eduardo Serrano-Yébenes
- Youssef Allaoua-Moussaoui
- Felix Mañes-Jiménez
- Rubén Jiménez-Martín
- Laura Jiménez-Alvarez
- Diego Córdova-Garcia
- Manuel Mariano Diez-Alonso
- Alberto Gutiérrez-Calvo
View Affiliations / Copyright

Affiliations: General Surgery Service, Príncipe de Asturias University Hospital, Alcalá de Henares, 28805 Madrid, Spain

Copyright: © Laguna-Hernández et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
Article Number: 15
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Published online on: March 1, 2023

https://doi.org/10.3892/mi.2023.75
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Abstract

Uterine carcinosarcoma (UCS) is a high‑grade endometrial cancer characterized by two components: Carcinomatous (epithelial) and sarcomatous (stromal tissue) elements. The present study describes a clinical case of this type of UCS and also provides a brief literature review of this type of tumor. A 72‑year‑old female visited the emergency department of the authors' hospital with pain in the hypogastric region, intestinal dysrhythmia since 3 months prior, fever and a palpable abdominal mass. Laboratory test results revealed sepsis and mild anemia and an imaging test revealed a large uterine tumor with wide areas of necrosis and adenopathies. As determined by the multidisciplinary committee, surgery was considered the main treatment option and this was performed with no incidences. Carcinosarcoma is a rare tumor, which most frequently occurs in older women. The diagnosis is based on symptoms and imaging tests, such as ecography and scans. The gold standard of treatment is surgery, although it is possible that other types of therapies, such as chemotherapy and radiotherapy may also be effective, depending on the tumor stage. On the whole, the prognosis of patients with this type of tumor is poor, with a low survival rate, even in earlier stages due to its malignant component and the possibility for metastasis. Surgery is the optimal treatment for this type of tumor, if this is possible, always individualizing patients.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Uterine carcinosarcoma with intestinal involvement: A case report and literature review

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