Potassium permanganate use in the management of a wound induced by contact with Paederus: A case report
Affiliations: Department of Psychology and Human Communication Therapy, University of Durango, Durango 81301, Mexico, Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, Mexico, Department of Research, Consultoria Larbas, Colima 28000, Mexico, Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, Mexico, Department of Research, General Hospital of Zone No. 1 IMSS, Villa de Alvarez, Colima 28984, Mexico, Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, Mexico, Molecular and Structural Physiology Laboratory, School of Biological Sciences, Autonomous University of Nuevo León, San Nicolás de los Garza, Nuevo León 66455, Mexico
- Published online on: March 21, 2023 https://doi.org/10.3892/mi.2023.81
- Article Number: 21
Copyright: © Lara-Esqueda et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
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Pederin is a vesicant toxic amide, found in the hemolymph of the beetle genus, Paederus. Physical contact with these insects produces a type of irritant dermatitis with variable clinical symptoms. It has been identified that Pederin (a vesicant toxic amide responsible for the ulcerative lesion) is produced by Gram‑negative endosymbiotic bacteria of the Pseudomonas genus. The present study describes the case of a patient who had come into contact with the insect Paederus sp. and developed an ulcerative lesion. He was first treated with topical steroids, as part of the conventional management, and following no response to treatment, he was treated locally with a 5% potassium permanganate solution, in conjunction with systemic antibiotic therapy, obtaining a good response in the healing process. On the whole, the present study demonstrates that potassium permanganate solutions, in conjunction with antibiotics and anti‑inflammatories, may be beneficial in the treatment of dermatitis or ulcerative lesions caused by insects of the Paederus genus. However, further research is required to fully determine the complete benefits and any side‑effects.