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Print ISSN: 2754-3242 Online ISSN: 2754-1304
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January-February 2024 Volume 4 Issue 1

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Case Report Open Access

Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report

  • Authors:
    • Masahiro Manabe
    • Yoko Tani
    • Naoyuki Inano
    • Yuuji Hagiwara
    • Nobuhiro Sogabe
    • Satoru Nanno
    • Ki-Rhang Koh
  • View Affiliations / Copyright

    Affiliations: Department of Hematology, Osaka General Hospital of West Japan Railway Company, Osaka 545‑0053, Japan, Department of Clinical Oncology, Osaka Metropolitan University Graduate School of Medicine, Osaka 545‑8585, Japan, Department of Clinical Laboratory, Osaka General Hospital of West Japan Railway Company, Osaka 545‑0053, Japan
    Copyright: © Manabe et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 9
    |
    Published online on: January 11, 2024
       https://doi.org/10.3892/mi.2024.133
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Abstract

The present study reports the case of a patient with acute myeloid leukemia post‑cytotoxic therapy (AML‑pCT) that developed following chemotherapy for thymoma. A 64‑year‑old female patient underwent surgical resection for a mediastinal tumor and was diagnosed with stage IVa thymoma. She received chemotherapy, including carboplatin/etoposide, carboplatin/paclitaxel and amrubicin monotherapy. At 56 months following surgery, she developed blastosis and was diagnosed with AML‑pCT. As demonstrated herein, although treatment for thymoma is associated with a markedly lower frequency of myeloid neoplasms post‑cytotoxic therapy (MN‑pCT) than treatment for other malignancies, such as breast carcinoma, it is important to be aware that MN‑pCT may occur as a late complication of thymoma treatment.
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Copy and paste a formatted citation
Spandidos Publications style
Manabe M, Tani Y, Inano N, Hagiwara Y, Sogabe N, Nanno S and Koh K: Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report. Med Int 4: 9, 2024.
APA
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., & Koh, K. (2024). Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report. Medicine International, 4, 9. https://doi.org/10.3892/mi.2024.133
MLA
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., Koh, K."Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report". Medicine International 4.1 (2024): 9.
Chicago
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., Koh, K."Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report". Medicine International 4, no. 1 (2024): 9. https://doi.org/10.3892/mi.2024.133
Copy and paste a formatted citation
x
Spandidos Publications style
Manabe M, Tani Y, Inano N, Hagiwara Y, Sogabe N, Nanno S and Koh K: Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report. Med Int 4: 9, 2024.
APA
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., & Koh, K. (2024). Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report. Medicine International, 4, 9. https://doi.org/10.3892/mi.2024.133
MLA
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., Koh, K."Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report". Medicine International 4.1 (2024): 9.
Chicago
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., Koh, K."Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report". Medicine International 4, no. 1 (2024): 9. https://doi.org/10.3892/mi.2024.133
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