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Neurological and systemic effects of cocaine toxicity: A case report and review of the literature

  • Authors:
    • Zachary M. Hong
    • Julie A. Kromm
  • View Affiliations / Copyright

    Affiliations: Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada, Department of Critical Care Medicine, Cumming School of Medicine, Foothills Medical Centre, McCaig Tower, Calgary, AB T2N 5A1, Canada
    Copyright: © Hong et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 72
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    Published online on: October 8, 2024
       https://doi.org/10.3892/mi.2024.196
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Abstract

While historically utilized as a topical anesthetic and active ingredient in a variety of tonics, beverages and cure‑alls, cocaine is a commonly abused illicit substance. Cocaine use is associated with a variety of neurological and systemic complications. The present study describes the case of a 23‑year‑old female patient presenting with profound neurological and systemic complications of cocaine, including coma, leukoencephaloapthy, neurogenic stunned myocardium, transaminitis, acute kidney injury, rhabdomyolysis and mononeuropathy. The supportive management and subsequent outcomes of the patients are discussed in detail. The approach to coma is also discussed, including stabilization and supportive care, diagnostic considerations and management. Key considerations relating prognosticating disorders of consciousness are also highlighted.
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Copy and paste a formatted citation
Spandidos Publications style
Hong ZM and Kromm JA: Neurological and systemic effects of cocaine toxicity: A case report and review of the literature. Med Int 4: 72, 2024.
APA
Hong, Z.M., & Kromm, J.A. (2024). Neurological and systemic effects of cocaine toxicity: A case report and review of the literature. Medicine International, 4, 72. https://doi.org/10.3892/mi.2024.196
MLA
Hong, Z. M., Kromm, J. A."Neurological and systemic effects of cocaine toxicity: A case report and review of the literature". Medicine International 4.6 (2024): 72.
Chicago
Hong, Z. M., Kromm, J. A."Neurological and systemic effects of cocaine toxicity: A case report and review of the literature". Medicine International 4, no. 6 (2024): 72. https://doi.org/10.3892/mi.2024.196
Copy and paste a formatted citation
x
Spandidos Publications style
Hong ZM and Kromm JA: Neurological and systemic effects of cocaine toxicity: A case report and review of the literature. Med Int 4: 72, 2024.
APA
Hong, Z.M., & Kromm, J.A. (2024). Neurological and systemic effects of cocaine toxicity: A case report and review of the literature. Medicine International, 4, 72. https://doi.org/10.3892/mi.2024.196
MLA
Hong, Z. M., Kromm, J. A."Neurological and systemic effects of cocaine toxicity: A case report and review of the literature". Medicine International 4.6 (2024): 72.
Chicago
Hong, Z. M., Kromm, J. A."Neurological and systemic effects of cocaine toxicity: A case report and review of the literature". Medicine International 4, no. 6 (2024): 72. https://doi.org/10.3892/mi.2024.196
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