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A rare presentation of subphrenic abscess caused by Proteus mirabilis in a non‑immunocompromised patient: A case report

  • Authors:
    • Lasha Chkhikvadze
    • Elisabed Chikobava
    • Nino Kantaria
  • View Affiliations / Copyright

    Affiliations: American MD Program, Tbilisi State Medical University, 0186 Tbilisi, Georgia, Department of Internal Medicine, New Hospitals, 0162 Tbilisi, Georgia
    Copyright: © Chkhikvadze et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 50
    |
    Published online on: June 17, 2025
       https://doi.org/10.3892/mi.2025.249
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Abstract

Subphrenic abscesses are rare, yet clinically significant, and are often associated with intra‑abdominal infections. The present case report describes the case of a 77‑year‑old male patient with an unusual presentation of a subphrenic abscess caused by Proteus mirabilis without typical predisposing factors. The patient experienced a prolonged 2‑year course characterized by recurrent febrile episodes and respiratory symptoms. The diagnosis was confirmed through imaging and microbiological culture, with percutaneous drainage and culture‑directed antibiotic therapy, including meropenem, leading to successful treatment. The multidrug‑resistant nature of the pathogen, coupled with the atypical presentation of the patient, posed significant challenges in both diagnosis and management. The case described herein underscores the importance of comprehensive diagnostic imaging, timely intervention and individualized treatment strategies in managing such complex infections.
View Figures

Figure 1

Computed tomography images
illustrating a complex cystic mass measuring 11.5 cm in diameter,
located in the right subdiaphragmatic region, extending into the
thoracic soft tissue at the 7th and 8th intercostal spaces. The
mass involved the right pleura and middle lobe of the lung,
exerting compressive effects on the right liver lobe. Atelectasis
was observed in the lower and middle lobes of the right lung and
the lower lobe of the left lung. A small right-sided pleural
effusion was also noted. The image on the left panel represents the
upper axial slice, illustrating the superior aspect of the
subdiaphragmatic abscess. The image on the right panel represents
the lower axial slice, providing clearer visualization of the
caudal extent of the abscess. Yellow arrows indicate the abscess in
both images.
View References

1 

Carter R and Brewer LA III: Subphrenic Abscess: A Thoracoabdominal Clinical Complex: The Changing Picture with Antibiotics. Am J Surg. 108:165–174. 1964.PubMed/NCBI View Article : Google Scholar

2 

Ravi GK and Puckett Y: Subphrenic Abscess. In: StatPearls. StatPearls Publishing, Treasure Island, FL, 2024.

3 

Jamil RT, Foris LA and Snowden J: Proteus mirabilis Infections. In: StatPearls. StatPearls Publishing, Treasure Island, FL, 2024.

4 

Rink AD, Stass H, Delesen H, Kubitza D and Vestweber KH: Pharmacokinetics and tissue penetration of moxifloxacin in intervention therapy for intra-abdominal abscess. Clin Drug Investig. 28:71–79. 2008.PubMed/NCBI View Article : Google Scholar

5 

DeCrosse JJ, Poulin TL, Fox PS and Condon RE: Subphrenic abscess. Surg Gynecol Obstet. 138:841–846. 1974.PubMed/NCBI

6 

Wang SM and Wilson SE: Subphrenic Abscess: The new epidemiology. Arch Surg. 112:934–936. 2025.PubMed/NCBI View Article : Google Scholar

7 

Karki A, Riley L, Mehta HJ and Ataya A: Abdominal etiologies of pleural effusion. Dis Mon. 65:95–103. 2019.PubMed/NCBI View Article : Google Scholar

8 

Parnasa E, Cohen A, Avital B, Parnasa YS and Oster Y: An unusual case of breast abscess caused by Proteus mirabilis and Prevotella buccalis. J Clin Images Med Case Rep. 2(1406)2021.

9 

Muddassir R, Khalil A, Singh R, Taj S and Khalid Z: Intracranial abscess and proteus mirabilis: A case report and literature review. Cureus. 12(e12326)2020.PubMed/NCBI View Article : Google Scholar

10 

Chung MH, Kim G, Han A and Lee J: Case report of neonatal proteus mirabilis meningitis and brain abscess with negative initial image finding: Consideration of serial imaging studies. Neonatal Med. 24:187–191. 2017.

11 

Moskaļenko KJ, Aveniņa S, Jeršovs K, Malzubris M and Golubovska I: Iliopsoas muscle abscess and Proteus mirabilis caused sepsis: a case report. Int J Sci Rep. 9:1–4. 2023.

12 

Umar BM: Intraabdominal Abscesses. In: Abscess-Types, Causes and Treatment. IntechOpen, London, 2024. Accessed on January 3, 2025.

13 

Kakuchi Y: Multiple renal abscesses due to Proteus mirabilis. Clin Exp Nephrol. 25:322–323. 2021.PubMed/NCBI View Article : Google Scholar

14 

Vakil N, Hayne G, Sharma A, Hardy DJ and Slutsky A: Liver abscess in Crohn's disease. Am J Gastroenterol. 89:1090–1095. 1994.PubMed/NCBI

15 

Frazier EH: Microbiology of subphrenic abscesses: a 14-year experience. Am Surg. 65:1049–1053. 1999.PubMed/NCBI

16 

O'Hara CM, Brenner FW and Miller JM: Classification, identification, and clinical significance of proteus, providencia, and morganella. Clin Microbiol Rev. 13:534–546. 2000.PubMed/NCBI View Article : Google Scholar

17 

Wu JJ, Chen HM, Ko WC, Wu HM, Tsai SH and Yan JJ: Prevalence of extended-spectrum beta-lactamases in Proteus mirabilis in a Taiwanese university hospital, 1999 to 2005: Identification of a novel CTX-M enzyme (CTX-M-66). Diagn Microbiol Infect Dis. 60:169–175. 2008.PubMed/NCBI View Article : Google Scholar

18 

Valentin T, Feierl G, Masoud-Landgraf L, Kohek P, Luxner J and Zarfel G: Proteus mirabilis harboring carbapenemase NDM-5 and ESBL VEB-6 detected in Austria. Diagn Microbiol Infect Dis. 91:284–286. 2018.PubMed/NCBI View Article : Google Scholar

19 

Bedenić B, Pospišil M, Nad M and Pavlović DB: Evolution of β-Lactam Antibiotic Resistance in Proteus Species: From Extended-Spectrum and Plasmid-Mediated AmpC β-Lactamases to Carbapenemases. Microorganisms. 13(508)2025.PubMed/NCBI View Article : Google Scholar

20 

Alqurashi E, Elbanna K, Ahmad I and Abulreesh HH: Antibiotic Resistance in Proteus mirabilis: Mechanism, Status, and Public Health Significance. J Pure Appl Microbiol. 1–12. 2022.

21 

Saha A, Chakraborty R, Sain B, Basak S and Saha S: A Case of Bilateral Subphrenic Abscess Mimicking Bilateral Postoperative Pleural Effusion. Bengal Phys J. 9:68–72. 2023.

22 

Shavrina NV, Ermolov AS, Yartsev PA, Kirsanov II, Khamidova LT, Oleynik MG and Tarasov SA: [Ultrasound in the diagnosis and treatment of abdominal abscesses]. Khirurgiia (Mosk). (11):29–36. 2019.PubMed/NCBI View Article : Google Scholar : (In Russian).

23 

Cho KH, Jung KH, Hwang MS, Chang JC, Kwun KB and Min HS: Ultrasonographic Features of Intra-abdominal Abscess. J Yeungnam Med Sci. 2(87)1985.

24 

Stevens C, Scott D, Ramesh P, Ragland A, Johnson C, Strobel J, Malone K, D'Agostino H, Ahuja C and De Alba L: The evolution of percutaneous abdominal abscess drainage: A review. Medicine (Baltimore). 104(e41799)2025.PubMed/NCBI View Article : Google Scholar

25 

Fry DE: Noninvasive imaging tests in the diagnosis and treatment of intra-abdominal abscesses in the postoperative patient. Surg Clin North Am. 74:693–709. 1994.PubMed/NCBI

26 

Liu S, Tian Z, Jiang Y, Mao T, Ding X and Jing X: Endoscopic ultrasound-guided drainage to abdominal abscess: A systematic review and meta-analysis. J Minimal Access Surg. 18:489–496. 2022.PubMed/NCBI View Article : Google Scholar

27 

De Filippo M, Puglisi S, D'Amuri F, Gentili F, Paladini I, Carrafiello G, Maestroni U, Del Rio P, Ziglioli F and Pagnini F: CT-guided percutaneous drainage of abdominopelvic collections: A pictorial essay. Radiol Med. 126:1561–1570. 2021.PubMed/NCBI View Article : Google Scholar

28 

Betsch A, Wiskirchen J, Trübenbach J, Manncke KH, Belka C, Claussen CD and Duda SH: CT-guided percutaneous drainage of intra-abdominal abscesses: APACHE III score stratification of 1-year results. Acute Physiology, Age, Chronic Health Evaluation. Eur Radiol. 12:2883–2889. 2002.PubMed/NCBI View Article : Google Scholar

29 

Hemming A, Davis NL and Robins RE: Surgical versus percutaneous drainage of intra-abdominal abscesses. Am J Surg. 161:593–595. 1991.PubMed/NCBI View Article : Google Scholar

30 

Mazuski JE, Tessier JM, May AK, Sawyer RG, Nadler EP, Rosengart MR, Chang PK, O'Neill PJ, Mollen KP, Huston JM, et al: The surgical infection society revised guidelines on the management of intra-abdominal infection. Surg Infect (Larchmt). 18:1–76. 2017.PubMed/NCBI View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Chkhikvadze L, Chikobava E and Kantaria N: A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report. Med Int 5: 50, 2025.
APA
Chkhikvadze, L., Chikobava, E., & Kantaria, N. (2025). A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report. Medicine International, 5, 50. https://doi.org/10.3892/mi.2025.249
MLA
Chkhikvadze, L., Chikobava, E., Kantaria, N."A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report". Medicine International 5.5 (2025): 50.
Chicago
Chkhikvadze, L., Chikobava, E., Kantaria, N."A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report". Medicine International 5, no. 5 (2025): 50. https://doi.org/10.3892/mi.2025.249
Copy and paste a formatted citation
x
Spandidos Publications style
Chkhikvadze L, Chikobava E and Kantaria N: A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report. Med Int 5: 50, 2025.
APA
Chkhikvadze, L., Chikobava, E., & Kantaria, N. (2025). A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report. Medicine International, 5, 50. https://doi.org/10.3892/mi.2025.249
MLA
Chkhikvadze, L., Chikobava, E., Kantaria, N."A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report". Medicine International 5.5 (2025): 50.
Chicago
Chkhikvadze, L., Chikobava, E., Kantaria, N."A rare presentation of subphrenic abscess caused by <em>Proteus mirabilis</em> in a non‑immunocompromised patient: A case report". Medicine International 5, no. 5 (2025): 50. https://doi.org/10.3892/mi.2025.249
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