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Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial

  • Authors:
    • Setu Katyal
    • Poonam Bogra
    • Rajinder Kumar Bansal
    • Vishakha Grover
    • Saurabh Gupta
    • Saru Dhir Gupta
  • View Affiliations / Copyright

    Affiliations: Department of Conservative Dentistry and Endodontics, I.T.S Dental College, Murad Nagar, Ghaziabad, Uttar Pradesh 201206, India, Department of Conservative Dentistry and Endodontics, J N Kapoor D.A.V. Dental College and Hospital, Yamunanagar, Haryana 135001, India, Department of Conservative Dentistry and Endodontics, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab 148028, India, Department of Periodontics, Dr Harvansh Singh Judge Institute of Dental Sciences and Hospital, Panjab University, Chandigarh 160014, India, Department of Conservative Dentistry and Endodontics, Maharishi Markandeshwar College of Dental Sciences, Ambala, Haryana 133207, India
    Copyright: © Katyal et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 55
    |
    Published online on: July 22, 2025
       https://doi.org/10.3892/mi.2025.254
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Abstract

The present study aimed to evaluate the effects of cryotherapy in conjunction with inferior alveolar nerve block (IANB) on intraoperative pain and anaesthesia success in adult patients with symptomatic irreversible pulpitis (SIP) of the mandibular permanent first molars. A total of 60 patients diagnosed with SIP of the mandibular first molars were randomly divided into two groups (n=30) as follows: Group I (the control), in which patients were administered IANB with 3.6 ml 2% lignocaine, and group II (test group), in which patients received the same IANB therapy followed by cryotherapy using an endo‑frost spray and intrapulpal ice sticks. Pain scores were recorded during access opening and cleaning/shaping using the Heft‑Parker visual analogue scale (VAS). The primary outcome was the success rate of anaesthesia (VAS ≤54 mm). The secondary outcome was mean pain score during the treatment phase. Group II exhibited a higher success rate (79.3%) than group I (65.3%) (P=0.24). The mean pain during access opening was significantly lower in group II (20.60±29.90) than in group I (41.43±43.10) (P=0.04). Although pain scores during cleaning/shaping were lower in group II (17.73±24.06 vs. 26.95±36.72), the difference was not statistically significant (P=0.27). On the whole, the present study demonstrates that cryotherapy improved anaesthetic success and reduced intraoperative pain during access opening in patients with SIP. However, its effect during subsequent treatment stages was limited, suggesting the need for supplemental anaesthesia in some cases.
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Spandidos Publications style
Katyal S, Bogra P, Bansal RK, Grover V, Gupta S and Gupta SD: Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial. Med Int 5: 55, 2025.
APA
Katyal, S., Bogra, P., Bansal, R.K., Grover, V., Gupta, S., & Gupta, S.D. (2025). Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial. Medicine International, 5, 55. https://doi.org/10.3892/mi.2025.254
MLA
Katyal, S., Bogra, P., Bansal, R. K., Grover, V., Gupta, S., Gupta, S. D."Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial". Medicine International 5.5 (2025): 55.
Chicago
Katyal, S., Bogra, P., Bansal, R. K., Grover, V., Gupta, S., Gupta, S. D."Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial". Medicine International 5, no. 5 (2025): 55. https://doi.org/10.3892/mi.2025.254
Copy and paste a formatted citation
x
Spandidos Publications style
Katyal S, Bogra P, Bansal RK, Grover V, Gupta S and Gupta SD: Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial. Med Int 5: 55, 2025.
APA
Katyal, S., Bogra, P., Bansal, R.K., Grover, V., Gupta, S., & Gupta, S.D. (2025). Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial. Medicine International, 5, 55. https://doi.org/10.3892/mi.2025.254
MLA
Katyal, S., Bogra, P., Bansal, R. K., Grover, V., Gupta, S., Gupta, S. D."Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial". Medicine International 5.5 (2025): 55.
Chicago
Katyal, S., Bogra, P., Bansal, R. K., Grover, V., Gupta, S., Gupta, S. D."Cryotherapy as a supplementary aid to inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: A randomized controlled trial". Medicine International 5, no. 5 (2025): 55. https://doi.org/10.3892/mi.2025.254
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