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Medicine International
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Print ISSN: 2754-3242 Online ISSN: 2754-1304
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March-April 2026 Volume 6 Issue 2

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

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International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Case Report Open Access

Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report

  • Authors:
    • Kana Yamada
    • Makoto Adachi

  • View Affiliations / Copyright

    Affiliations: Department of Anesthesiology, Nagoya Tokushukai General Hospital, Kasugai, Aichi 487‑0016, Japan, Department of Oral and Maxillofacial Surgery, Nagoya Tokushukai General Hospital, Kasugai, Aichi 487‑0016, Japan
    Copyright: © Yamada et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 17
    |
    Published online on: February 11, 2026
       https://doi.org/10.3892/mi.2026.301
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Abstract

Throat packs are routinely inserted during oral and maxillofacial surgery and are generally considered safe. However, severe vagally mediated cardiovascular reflexes can rarely occur during airway or oropharyngeal manipulation. The present study describes a rare case of cardiac arrest directly attributed to throat pack insertion. A healthy 54‑year‑old male patient underwent third molar extraction under general anesthesia. Immediately following throat pack placement, he developed sudden cardiac arrest with complete electrical asystole lasting ~20 sec. Spontaneous circulation returned rapidly following the intravenous administration of ephedrine (8 mg) without the need for chest compressions. This event was most consistent with a vagal reflex‑mediated response. The present case report indicates that vigilant hemodynamic monitoring, adequate ventilation and appropriate anesthetic depth are essential even during routine adjunctive steps, such as throat pack insertion.

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Copy and paste a formatted citation
Spandidos Publications style
Yamada K and Adachi M: <p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>. Med Int 6: 17, 2026.
APA
Yamada, K., & Adachi, M. (2026). <p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>. Medicine International, 6, 17. https://doi.org/10.3892/mi.2026.301
MLA
Yamada, K., Adachi, M."<p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>". Medicine International 6.2 (2026): 17.
Chicago
Yamada, K., Adachi, M."<p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>". Medicine International 6, no. 2 (2026): 17. https://doi.org/10.3892/mi.2026.301
Copy and paste a formatted citation
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Spandidos Publications style
Yamada K and Adachi M: <p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>. Med Int 6: 17, 2026.
APA
Yamada, K., & Adachi, M. (2026). <p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>. Medicine International, 6, 17. https://doi.org/10.3892/mi.2026.301
MLA
Yamada, K., Adachi, M."<p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>". Medicine International 6.2 (2026): 17.
Chicago
Yamada, K., Adachi, M."<p>Cardiac arrest complicating routine throat pack insertion in oral and maxillofacial surgery under general anesthesia: A case report</p>". Medicine International 6, no. 2 (2026): 17. https://doi.org/10.3892/mi.2026.301
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