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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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May-June 2008 Volume 1 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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May-June 2008 Volume 1 Issue 3

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Review

Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review)

  • Authors:
    • Katarzyna A. Trzaska
    • Marianne D. Castillo
    • Pranela Rameshwar

  • View Affiliations / Copyright

    Affiliations: Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
  • Pages: 307-316
    |
    Published online on: May 1, 2008
       https://doi.org/10.3892/mmr.1.3.307
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Abstract

Mesenchymal stem cells (MSCs) are an attractive cell source for regenerative medicine as they can be easily isolated from bone marrow (BM) aspirates and expanded in culture while maintaining their ‘stemness’. In addition to differentiating into mesodermal cells, MSCs have shown considerable plasticity and generate ectodermal neurons and glia, which can be used to replace cells damaged by neurological diseases and injuries. These unique stem cells also exhibit immunomodulatory functions and secrete a variety of trophic factors which support regeneration and repair. This review focuses on the therapeutic usage of MSCs for neurodegenerative diseases and traumatic injuries to the nervous system. Animal studies demonstrate great promise for MSC transplantation in neurological disorders. In fact, a few clinical trials have already been initiated and show that MSCs are a safe cellular therapy and have great potential to become a viable treatment for neural disorders in the years to come.

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Copy and paste a formatted citation
Spandidos Publications style
Trzaska KA, Castillo MD and Rameshwar P: Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review). Mol Med Rep 1: 307-316, 2008.
APA
Trzaska, K.A., Castillo, M.D., & Rameshwar, P. (2008). Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review). Molecular Medicine Reports, 1, 307-316. https://doi.org/10.3892/mmr.1.3.307
MLA
Trzaska, K. A., Castillo, M. D., Rameshwar, P."Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review)". Molecular Medicine Reports 1.3 (2008): 307-316.
Chicago
Trzaska, K. A., Castillo, M. D., Rameshwar, P."Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review)". Molecular Medicine Reports 1, no. 3 (2008): 307-316. https://doi.org/10.3892/mmr.1.3.307
Copy and paste a formatted citation
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Spandidos Publications style
Trzaska KA, Castillo MD and Rameshwar P: Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review). Mol Med Rep 1: 307-316, 2008.
APA
Trzaska, K.A., Castillo, M.D., & Rameshwar, P. (2008). Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review). Molecular Medicine Reports, 1, 307-316. https://doi.org/10.3892/mmr.1.3.307
MLA
Trzaska, K. A., Castillo, M. D., Rameshwar, P."Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review)". Molecular Medicine Reports 1.3 (2008): 307-316.
Chicago
Trzaska, K. A., Castillo, M. D., Rameshwar, P."Adult mesenchymal stem cells in neural regeneration and repair: Current advances and future prospects (Review)". Molecular Medicine Reports 1, no. 3 (2008): 307-316. https://doi.org/10.3892/mmr.1.3.307
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