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Tapping an unexploited repository: Carnoy's fixed cell pellets for proteomic biomarker research in leukemia

  • Authors:
    • Ferdinand Von Eggeling
    • Annett Bleul
    • Ivan F. Loncarevic
    • Susanne Michel
    • Anita Heller
    • Christian Melle

  • View Affiliations

  • Published online on: July 1, 2008     https://doi.org/10.3892/mmr.1.4.585
  • Pages: 585-587
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
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Abstract

For chromosomal analysis in tumor genetics, cells from blood and bone marrow are prepared and preserved virtually indefinitely in Carnoy's fixative (methanol/acetic acid). Numerous samples are stored unvalued in hospitals and institutes worldwide. We developed a method to analyze proteins from even a small amount of these cells by mass spectrometry using affinity chromatographic surfaces (SELDI), and demonstrated the application of proteomic biomarker research in cases of acute myeloid leukemia.

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Journal Cover

July-August 2008
Volume 1 Issue 4

Print ISSN: 1791-2997
Online ISSN:1791-3004

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  • Journal Metrics
  • Impact Factor: 3.4
  • Ranked Medicine Research and Experimental
    (total number of cites)
  • CiteScore: 6.9
  • CiteScore Rank: Q2: #98/328 Biochemistry, Genetics and Molecular Biology
  • Source Normalized Impact per Paper (SNIP): 0.721
  • SCImago Journal Rank (SJR): 0.65
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Spandidos Publications style
Von Eggeling F, Bleul A, Loncarevic IF, Michel S, Heller A and Melle C: Tapping an unexploited repository: Carnoy's fixed cell pellets for proteomic biomarker research in leukemia. Mol Med Rep 1: 585-587, 2008
APA
Von Eggeling, F., Bleul, A., Loncarevic, I.F., Michel, S., Heller, A., & Melle, C. (2008). Tapping an unexploited repository: Carnoy's fixed cell pellets for proteomic biomarker research in leukemia. Molecular Medicine Reports, 1, 585-587. https://doi.org/10.3892/mmr.1.4.585
MLA
Von Eggeling, F., Bleul, A., Loncarevic, I. F., Michel, S., Heller, A., Melle, C."Tapping an unexploited repository: Carnoy's fixed cell pellets for proteomic biomarker research in leukemia". Molecular Medicine Reports 1.4 (2008): 585-587.
Chicago
Von Eggeling, F., Bleul, A., Loncarevic, I. F., Michel, S., Heller, A., Melle, C."Tapping an unexploited repository: Carnoy's fixed cell pellets for proteomic biomarker research in leukemia". Molecular Medicine Reports 1, no. 4 (2008): 585-587. https://doi.org/10.3892/mmr.1.4.585