|
1
|
Jorgensen NR, Henriksen Z, Sorensen OH and
Civitelli R: Dexamethasone, BMP-2, and 1, 25-dihydroxyvitamin D
enhance a more differentiated osteoblast phenotype: validation of
an in vitro model for human bone marrow-derived primary
osteoblasts. Steroids. 69:219–226. 2004. View Article : Google Scholar
|
|
2
|
Shin JH, Kim KH, Kim SH, et al: Ex vivo
bone morphogenetic protein-2 gene delivery using gingival
fibroblasts promotes bone regeneration in rats. J Clin Periodontol.
37:305–311. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cheng H, Jiang W, Phillips FM, et al:
Osteogenic activity of the fourteen types of human bone
morphogenetic proteins (BMPs). Bone Joint Surg Am. 85:1544–1552.
2003.PubMed/NCBI
|
|
4
|
Wan C, Gilbert SR, Wang Y, et al:
Activation of the hypoxia-inducible factor-1-alpha pathway
accelerates. Proc Nat Acad Sci U S A. 105:686–691. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hua Z, Nicola JM, Margaret TM and Simons
J: Nuclear expression of hypoxia-inducible factor 1alpha protein is
heterogeneous in human malignantcells under normoxic conditions.
Cancer Lett. 181:2332002. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang Y, Wan C, Deng L, et al: The
hypoxia-inducible factor alpha pathway couples angiogenesis to
osteogenesis during skeletal development. J Clin Invest.
117:1616–1626. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Giaccia A, Siim BG and Johnson RS: HIF-1
as a target for drug development. Nat Rev Drug Discov. 2:803–811.
2003. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Diab T, Pritchard EM, Uhrig BA, Boerckel
JD, Kaplan DL and Guldberg RE: A silk hydrogel-based delivery
system of bone morphogenetic protein for the treatment of large
bone defects. J Mech Behav Biomed Mater. 11:123–131. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wigner NA, Luderer HF, Cox MK, Sooy K,
Gerstenfeld LC and Demay MB: Acute phosphate restriction leads to
impaired fracture healing and resistance to BMP-2. J Bone Miner
Res. 25:724–733. 2010.PubMed/NCBI
|
|
10
|
Kim TH, Oh SH, Na SY, Chun SY and Lee JH:
Effect of biological/physical stimulation on guided bone
regeneration through asymmetrically porous membrane. J Biomed Mater
Res A. 100:1512–1520. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chang SC, Lin TM, Chung HY, et al:
Large-scale bicortical skull bone regeneration using ex vivo
replication-defective adenoviral-mediated bone morphogenetic
protein-2 gene-transferred bone marrow stromal cells and composite
biomaterials. Neurosurgery. 65:75–81. 2009. View Article : Google Scholar
|
|
12
|
Liu Y, Lu Y, Tian X, et al: Fragmental
bone regeneration using an rhBMP-2-loaded
gelatin/nanohydroxyapatite/fibrin scaffold in a rabbit model.
Biomaterials. 30:6276–6285. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Baltzer AW, Ostapczuk MS, Stosch D and
Granrath M: The use of recombinant human bone morphogenetic
protein-2 for the treatment of a delayed union following femoral
neck open-wedge osteotomy. Orthop Rev (Pavia). 4:e42012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kanczler JM, Ginty PJ, White L, et al: The
effect of the delivery of vascular endothelial growth factor and
bone morphogenic protein-2 to osteoprogenitor cell populations on
bone formation. Biomaterials. 31:1242–1250. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Kang SW, Bae JH, Park SA, et al:
Combination therapy with BMP-2 and BMSCs enhances bone healing
efficacy of PCL scaffold fabricated using the 3D plotting system in
a large fragmental defect model. Biotechnol Lett. 34:1375–1384.
2012. View Article : Google Scholar
|
|
16
|
Simon F, Bockhorn M, Praha C, et al:
Deregulation of HIF1-alpha and hypoxia- regulated pathways in
hepatocellular carcinoma and corresponding non-malignant liver
tissue--influence of a modulated host stroma on the prognosis of
HCC. Langenbecks Arch Surg. 395:395–405. 2010. View Article : Google Scholar
|
|
17
|
Lando D, Peet DJ, Whelan DA, Gorman JJ and
Whitelaw ML: Asparagine hydroxylation of the HIF transactivation
domain a hypoxic switch. Science. 295:858–861. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lim W, Cho J, Kwon HY, Park Y, Rhyu MR and
Lee Y: Hypoxia-inducible factor 1 alpha activates and is inhibited
by unoccupied estrogen receptor beta. FEBS Lett. 583:1314–1318.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Elson DA, Thurston G, Huang LE, et al:
Induction of hypervascularity without leakage or inflammation in
transgenic mice overexpressing hypoxia-inducible factor-1alpha.
Genes Dev. 15:2520–2532. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Liu DP, Wang GX, Hu L and Li C:
Construction of adenovirus-mediated eukaryotic expression vector
co-expressing mutant hypoxia-inducible factor-1 alpha target
protein and humanized Renilla reniformis green fluorescent protein
reporter molecule under normoxic conditions. J Clin Rehab Tiss Eng
Res. 14:3787–3792. 2010.
|
