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September 2012 Volume 6 Issue 3

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Review

microRNAs in esophageal cancer (Review)

  • Authors:
    • Bin He
    • Bangliang Yin
    • Baoxiang Wang
    • Zhenkun Xia
    • Chen Chen
    • Jingqun Tang
  • View Affiliations / Copyright

    Affiliations: Department of Cardiothoracic Surgery, the Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China
  • Pages: 459-465
    |
    Published online on: June 29, 2012
       https://doi.org/10.3892/mmr.2012.975
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Abstract

Esophageal cancer (EC) is one of the most common malignant tumors worldwide. EC is usually diagnosed at a locally advanced stage or at a stage with involvement of lymph nodes. Despite aggressive treatment, the overall five-year survival rate remains poor. microRNAs (miRNAs) are small, non-coding endogenous RNAs that negatively regulate gene expression at the post-transcriptional and/or translational level. Accumulating evidence suggests that the deregulation of miRNAs not only results in cancer progression, but also directly promotes tumor initiation. Previous studies found that miRNAs are frequently deregulated in EC, indicating that miRNAs are important in tumorigenesis. In this review, we summarize therecently recognized miRNA expression and its impact on the biology of EC and the potential applications for EC.
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Copy and paste a formatted citation
Spandidos Publications style
He B, Yin B, Wang B, Xia Z, Chen C and Tang J: microRNAs in esophageal cancer (Review). Mol Med Rep 6: 459-465, 2012.
APA
He, B., Yin, B., Wang, B., Xia, Z., Chen, C., & Tang, J. (2012). microRNAs in esophageal cancer (Review). Molecular Medicine Reports, 6, 459-465. https://doi.org/10.3892/mmr.2012.975
MLA
He, B., Yin, B., Wang, B., Xia, Z., Chen, C., Tang, J."microRNAs in esophageal cancer (Review)". Molecular Medicine Reports 6.3 (2012): 459-465.
Chicago
He, B., Yin, B., Wang, B., Xia, Z., Chen, C., Tang, J."microRNAs in esophageal cancer (Review)". Molecular Medicine Reports 6, no. 3 (2012): 459-465. https://doi.org/10.3892/mmr.2012.975
Copy and paste a formatted citation
x
Spandidos Publications style
He B, Yin B, Wang B, Xia Z, Chen C and Tang J: microRNAs in esophageal cancer (Review). Mol Med Rep 6: 459-465, 2012.
APA
He, B., Yin, B., Wang, B., Xia, Z., Chen, C., & Tang, J. (2012). microRNAs in esophageal cancer (Review). Molecular Medicine Reports, 6, 459-465. https://doi.org/10.3892/mmr.2012.975
MLA
He, B., Yin, B., Wang, B., Xia, Z., Chen, C., Tang, J."microRNAs in esophageal cancer (Review)". Molecular Medicine Reports 6.3 (2012): 459-465.
Chicago
He, B., Yin, B., Wang, B., Xia, Z., Chen, C., Tang, J."microRNAs in esophageal cancer (Review)". Molecular Medicine Reports 6, no. 3 (2012): 459-465. https://doi.org/10.3892/mmr.2012.975
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