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Article

Neopterin: A potential marker in chronic peripheral arterial disease

  • Authors:
    • Salvatore Santo Signorelli
    • Massimiliano Anzaldi
    • Valerio Fiore
    • Saverio Candido
    • Roberto Di Marco
    • Katia Mangano
    • Cinzia Quattrocchi
    • Sergio Neri
  • View Affiliations / Copyright

    Affiliations: Department of Medical and Pediatric Science, Section of Internal and Vascular Medicine, University of Catania, Catania I‑95125, Italy, Department of Bio‑Medical Sciences, Section of Internal Medicine, University of Catania, Catania I‑95125, Italy, Department of Medical and Pediatric Science, Section of Internal Medicine, University of Catania, Catania I‑95125, Italy
  • Pages: 1855-1858
    |
    Published online on: April 2, 2013
       https://doi.org/10.3892/mmr.2013.1407
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Abstract

Neopterin is a marker of macrophage activation that has exhibited high plasma levels in atherosclerotic diseases including coronary heart disease and critical limb ischemia. The role of neopterin in chronic peripheral arterial disease (PAD) has yet to be elucidated. In the present study, neopterin (Ν) serum concentrations were analyzed in asymptomatic (AsP) and symptomatic (SyP) patients with PAD as well as controls (C). In total 120 subjects, 40 AsP [ankle brachial index (ABI) ≤0.90], 40 SyP (ABI ≤0.90 plus pain in legs) and 40 controls (ABI >0.9) were enrolled. The results of the present study showed that neopterin plasma levels were statistically different among the groups. These findings demonstrated that activation of N‑mediated monocyte‑macrophage, was also observed in chronic PAD.
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1 

Ross R: The pathogenesis of atherosclerosis: a prospective for the 1990s. Nature. 362:801–809. 1993. View Article : Google Scholar

2 

Libby P, Sukhova G, Lee RT and Galis ZS: Cytokines regulate vascular functions related to stability of the atherosclerotic plaque. J Cardiovasc Pharmacol. 25:S9–S12. 1995. View Article : Google Scholar : PubMed/NCBI

3 

Jacobs M, van Greevenbroek MM, van der Kallen CJ, Ferreira I, Blaak EE, Feskens EJ, Jansen EH, Schalkwijk CG and Stehouwer CD: Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study. Eur J Clin Invest. 39:437–444. 2009. View Article : Google Scholar

4 

Jenny NS, Yanez ND, Psaty BM, Kuller LH, Hirsh CH and Tracy RP: Inflammation biomarkers and near-term death in older man. Am J Epidemiol. 165:684–695. 2007. View Article : Google Scholar : PubMed/NCBI

5 

Yu H and Rifai N: High-sensitivity C-reactive protein and atherosclerosis: from theory to therapy. Clin Biochem. 33:601–610. 2000. View Article : Google Scholar : PubMed/NCBI

6 

Rifai N and Ridker PM: High-sensitivity C-reactive protein: a novel and promising marker of coronary heart disease. Clin Chem. 47:403–411. 2001.PubMed/NCBI

7 

Jenny NS, Arnold AM, Kuller LH, Tracy RP and Psaty BM: Serum amyloid P and cardiovascular disease in older men and women. Results from the cardiovascular health study. Arterioscler Thromb Vasc Biol. 27:352–358. 2007. View Article : Google Scholar : PubMed/NCBI

8 

Yang RZ, Lee MJ, Hu H, Pollin TI, Ryan AS, Nicklas BJ, Snitker S, Horenstein RB, Hull K, Goldberg NH, Goldberg AP, Shuldiner AR, Fried SK and Gong DW: Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PloS Med. 3:e2872006. View Article : Google Scholar : PubMed/NCBI

9 

O’Brien KD and Chait A: Serum amyloid A: the ‘other’ inflammatory protein. Curr Atheroscler Rep. 8:62–68. 2006.

10 

O’Brien KD, McDonald TO, Kunjathoor V, Eng K, Lewig K, Lopez R, Kirk EA, Chait A, Wight IN, de Beer FC and Le Boeuf BC: Serum amyloid A and lipoprotein retention in murine models of atherosclerosis. Arterioscler Thromb Vasc Biol. 25:785–790. 2005.PubMed/NCBI

11 

Unlu Y, Karapolat S, Karaca Y and Kiziltunc A: Comparison of levels of inflammatory markers and haemostatic factors in the patients with and without peripheral arterial disease. Thromb Res. 117:357–364. 2006. View Article : Google Scholar : PubMed/NCBI

12 

Flugelman MY, Virmani R, Correa R, Yu ZX, Farb A, Leon MB, Elami A, Fu YM, Casscells W and Epstein SE: Smooth muscle cells abundance and fibroblast growth factors in coronary lesions of patients with nonfatal unstable angina. A clue to the mechanism of transformation from the stable to unstable state. Circulation. 88:2493–2500. 1993. View Article : Google Scholar

13 

Tzoulaki I, Murray GD, Lee AJ, Rumley A, Lowe GD and Fowkes FG: C-reactive protein, interleukin-6, and soluble adhesion molecules as predictors of progressive peripheral atherosclerosis in the general population: Edinburgh Artery Study. Circulation. 112:976–983. 2005. View Article : Google Scholar

14 

McDermott MM, Guralnik JM, Corsi A, Albay M, Macchi C, Bandinelli S and Ferrucci L: Patterns of inflammation associated with peripheral arterial disease: the InCHIANTI study. Am Heart J. 150:276–281. 2005. View Article : Google Scholar : PubMed/NCBI

15 

Huber C, Batchelor JR, Fuchs D, Hausen A, Lang A, Niederwieser D, Reibnegger G, Swettly P, Troppmair J and Wacther H: Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma. J Exp Med. 160:310–316. 1984. View Article : Google Scholar

16 

Gupta S, Fredericks S, Scwartzman WA, Hot DW and Kaski JC: Serum neopterin in acute coronary syndrome. Lancet. 349:1252–1253. 1997. View Article : Google Scholar : PubMed/NCBI

17 

Avanzas P, Domínguez-Rodríguez A, Arroyo-Espliguero R and Kaski JC: Neopterin and coronary artery disease. J Cardiol. 54:344–345. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Fuchs D, Avanzas P, Arroyo-Espliguero R, Jenny M, Consuegra-Sanchez L and Kaski JC: The role of neopterin in atherogenesis and cardiovascular risk assessment. Curr Med Chem. 16:4644–4653. 2009. View Article : Google Scholar : PubMed/NCBI

19 

Nazer B, Ray KK, Sloan S, Scirica B, Morrow DA, Cannon CP and Braunwald E: Prognostic utility of neopterin and risk of heart failure hospitalization after an acute coronary syndrome. Eur Heart J. 32:1390–1397. 2011. View Article : Google Scholar : PubMed/NCBI

20 

Martin M, Gottsäter A, Nilsson PM, Mollnes TE, Lindblad B and Blom AM: Complement activation and plasma levels of C4b-binding protein in critical limb ischemia patients. J Vasc Surg. 50:100–106. 2009. View Article : Google Scholar : PubMed/NCBI

21 

van Haelst PL, Liem A, van Boven AJ, Veegre NJ, van Veldhuisen DJ, Tervaert JW, Gans RO and Zijlstra F: Usefulness of elevated neopterin and C-reactive protein levels in predicting cardiovascular events in patients with non-Q-wave myocardial infarction. Am J Cardiol. 92:1201–1203. 2003.PubMed/NCBI

22 

Fowkes FG: Epidemiology of atherosclerotic arterial disease of the lower limbs. Eur J Vasc Surg. 2:283–291. 1988. View Article : Google Scholar

23 

Aronow WS and Ahn C: Prevalence of coexistence of coronary artery disease, peripheral arterial disease and atherotrombotic brain infarction in men and women > or =62 years of age. Am J Cardiol. 74:64–65. 1994.PubMed/NCBI

24 

Agnelli G, Cimminiello C, Meneghetti G and Urbinati S: The Polyvascular Atherothrombosis Observational Survey (PATHOS) Investigators. Low ankle-brachial index predicts an adverse 1-year outcome after acute coronary and cerebrovascular events. J Thromb Haemost. 4:2599–2606. 2006.

25 

Santo Signorelli S, Anzaldi M, Fiore V, Catanzaro S, Simili M, Torrisi B and Neri S: Study on unrecognized peripheral arterial disease (PAD) by ankle/brachial index and arterial comorbidity in Catania, Sicily, Italy. Angiology. 61:524–529. 2010.PubMed/NCBI

26 

Westermann J, Thiermann F, Gerstetner L, Tatzber F, Kozak I, Bertsch T and Kruger C: Evaluation of a new simple and rapid enzyme-like-immunosorbent assay kit for neopterin determination. Clin Chem Lab Med. 38:345–353. 2000. View Article : Google Scholar : PubMed/NCBI

27 

Avanzas P, Arroyo-Espliguerro R, Coxin-Sales J, ldama G, Pizzi C, Quiles J and Kaski JC: Markers of inflammation and multiple complex stenoses (pancoronary plaque vulnerability) in patients with non-ST segment elevation acute coronary syndrome. Heart. 90:847–852. 2004. View Article : Google Scholar

28 

Sugioka K, Naruko T, Hozumi T, Nakagawa M, Kitabayashi C, Ikura Y, Shirai N, Matsumura Y, Ehara S, Ujino K, Itoh A, Haze K, Becker AE, Yoshiyama M and Ueda M: Elevated levels of neopterin are associated with carotid plaques with complex morphology in patients with stable angina pectoris. Atherosclerosis. 208:524–530. 2010. View Article : Google Scholar : PubMed/NCBI

29 

Weiss G, Fuchs D, Hausen A, Reibnegger G, Werner ER, Werner-Felmayer G, Semenitz E, Dierich MP and Wachter H: Neopterin modulates toxicity mediated by reactive oxygen and chloride species. FEBS Lett. 321:89–92. 1993. View Article : Google Scholar : PubMed/NCBI

30 

Murr C, fuchs D, Gossler W, Hausen A, Reibnegger G, Werner ER, Werner-Felmayer G, Esterbauer H and Wachter H: Ehnancement of hydrogen peroxide induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chaltor complexes. FEBS Lett. 338:223–226. 1994. View Article : Google Scholar : PubMed/NCBI

31 

Resnick HE, Linday RS, Mc Dermott MM, Deveraux RB, Jones KL, Fabsitz RR and Howard RR: Relationship between high and low ankle brachial index to all-cause and to cardiovascular disease mortality: the Strong Heart Study. Circulation. 109:733–739. 2004. View Article : Google Scholar : PubMed/NCBI

32 

Fiotti N, Giansante C, Ponte E, Delbello C, Calabrese S, Zacchi T, Dobrina A and Guarnieri G: Atherosclerosis and inflammation. Patterns of cytokine regulation in patients with peripheral arterial disease. Atherosclerosis. 145:51–60. 1999. View Article : Google Scholar : PubMed/NCBI

33 

Brevetti G, Silvestro A, Di Giacomo S, Bucur R, Di Donato A, Schiano V and Scopacasa F: Endothelial dysfunction in peripheral arterial disease is related to increase in plasma markers of inflammation and severity of peripheral circulatory impairment but not to classic risk factors and atherosclerotic burden. J Vasc Surg. 38:374–379. 2003. View Article : Google Scholar

34 

Schnabel RB, Schulz A, Messow CM, Lubos E, Wild PS, Zeller T, Sinning CR, Rupprecht HJ, Bickel C, Peetz D, Cambien F, Kempf T, Wollert KC, Benjamin EJ, Lackner KJ, Münzel TF, Tiret L, Vasan RS and Blankenberg S: Multiple marker approach to risk stratification in patients with stable coronary artery disease. Eur Heart J. 31:3024–3031. 2010. View Article : Google Scholar : PubMed/NCBI

35 

De Rosa S, Cirillo P, Pacileo M, Petrillo G, D’Ascoli GL, Maresca F, Ziviello F and Chiariello M: Neopterin: from forgotten biomarker to leading actor in cardiovascular pathophysiology. Curr Vasc Pharmacol. 9:188–199. 2011.PubMed/NCBI

36 

Signorelli SS, Malaponte G, Libra M, Di Pino L, Celotta G, Bevelacqua V, Petrina M, Nicotra GS, Indelicato M, Navolanic PM, Pennini G and Mazzarino MC: Plasma levels and zymographic activities of matrix metalloproteinases 2 and 9 in type II diabetics with peripheral arterial disease. Vasc Med. 10:1–6. 2005. View Article : Google Scholar : PubMed/NCBI

37 

Libra M, Signorelli SS, Bevelacqua Y, Navolanic PM, Bevelacqua V, Polesel J, Talamini R, Stivala F, Mazzarino MC and Malaponte G: Analysis of G(-174)C IL-6 polymorphism and plasma concentrations of inflammatory markers in patients with type 2 diabetes and peripheral arterial disease. J Clin Pathol. 59:211–215. 2006. View Article : Google Scholar : PubMed/NCBI

38 

Signorelli SS, Anzaldi M and Fiore V: Inflammation in peripheral arterial disease (PAD). Curr Pharm Des. 18:4350–4357. 2012. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Signorelli SS, Anzaldi M, Fiore V, Candido S, Di Marco R, Mangano K, Quattrocchi C and Neri S: Neopterin: A potential marker in chronic peripheral arterial disease. Mol Med Rep 7: 1855-1858, 2013.
APA
Signorelli, S.S., Anzaldi, M., Fiore, V., Candido, S., Di Marco, R., Mangano, K. ... Neri, S. (2013). Neopterin: A potential marker in chronic peripheral arterial disease. Molecular Medicine Reports, 7, 1855-1858. https://doi.org/10.3892/mmr.2013.1407
MLA
Signorelli, S. S., Anzaldi, M., Fiore, V., Candido, S., Di Marco, R., Mangano, K., Quattrocchi, C., Neri, S."Neopterin: A potential marker in chronic peripheral arterial disease". Molecular Medicine Reports 7.6 (2013): 1855-1858.
Chicago
Signorelli, S. S., Anzaldi, M., Fiore, V., Candido, S., Di Marco, R., Mangano, K., Quattrocchi, C., Neri, S."Neopterin: A potential marker in chronic peripheral arterial disease". Molecular Medicine Reports 7, no. 6 (2013): 1855-1858. https://doi.org/10.3892/mmr.2013.1407
Copy and paste a formatted citation
x
Spandidos Publications style
Signorelli SS, Anzaldi M, Fiore V, Candido S, Di Marco R, Mangano K, Quattrocchi C and Neri S: Neopterin: A potential marker in chronic peripheral arterial disease. Mol Med Rep 7: 1855-1858, 2013.
APA
Signorelli, S.S., Anzaldi, M., Fiore, V., Candido, S., Di Marco, R., Mangano, K. ... Neri, S. (2013). Neopterin: A potential marker in chronic peripheral arterial disease. Molecular Medicine Reports, 7, 1855-1858. https://doi.org/10.3892/mmr.2013.1407
MLA
Signorelli, S. S., Anzaldi, M., Fiore, V., Candido, S., Di Marco, R., Mangano, K., Quattrocchi, C., Neri, S."Neopterin: A potential marker in chronic peripheral arterial disease". Molecular Medicine Reports 7.6 (2013): 1855-1858.
Chicago
Signorelli, S. S., Anzaldi, M., Fiore, V., Candido, S., Di Marco, R., Mangano, K., Quattrocchi, C., Neri, S."Neopterin: A potential marker in chronic peripheral arterial disease". Molecular Medicine Reports 7, no. 6 (2013): 1855-1858. https://doi.org/10.3892/mmr.2013.1407
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