The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne

Zhu,Jiang-Ting; Xuan,Min; Zhang,Ya-Ni; Liu,Hong-Wei; Cai,Jin-Hui; Wu,Yan‑Hong; Xiang,Xiao-Fei; Shan,Gui-Qiu; Cheng,Biao

doi:10.3892/mmr.2013.1455

July 2013 Volume 8 Issue 1

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July 2013 Volume 8 Issue 1

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Article

The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne

Authors:
- Jiang-Ting Zhu
- Min Xuan
- Ya-Ni Zhang
- Hong-Wei Liu
- Jin-Hui Cai
- Yan‑Hong Wu
- Xiao-Fei Xiang
- Gui-Qiu Shan
- Biao Cheng
View Affiliations / Copyright

Affiliations: Department of Plastic Surgery, Guangzhou General Hospital of Guangzhou Military Command, The Key Laboratory of Trauma Treatment and Tissue Repair of Tropical Area, PLA, Guangzhou, Guangdong 510010, P.R. China, Department of Transfusion, Guangzhou General Hospital of Guangzhou Military Command, PLA, Guangzhou, Guangdong 510010, P.R. China, Department of Plastic Surgery, the First Affiliated Hospital of Jinan University, Key Laboratory for Regenerative Medicine, Ministry of Education, Guangzhou, Guangdong 510630, P.R. China, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China
Pages: 233-237
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Published online on: May 2, 2013

https://doi.org/10.3892/mmr.2013.1455
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Abstract

The aim of this study was to evaluate the efficacy of autologous platelet-rich plasma (PRP) combined with erbium fractional laser therapy for facial acne or acne scars. PRP combined with erbium fractional laser therapy was used for the treatment of 22 patients, including 16 patients who suffered from facial acne scars and 6 patients who suffered from acne scars concomitant with acne. Whole blood (40 ml) was collected from each patient, and following differential centrifugation, PRP was harvested. After using an erbium fractional laser, we applied PRP to the entire face of every patient. Digital photos were taken before and after the treatment for evaluation by dermatologists and the patients rated the efficacy on a 5-point scale. The erythema was moderate or mild, while its total duration was <3 days; after receiving the treatment three times, 90.9% of the patients showed an improvement of >50%, and 91% of the patients were satisfied; no acne inflammation was observed after treatment. PRP combined with erbium fractional laser therapy is an effective and safe approach for treating acne scars or acne, with minimal side-effects, and it simultaneously enhanced the recovery of laser-damaged skin.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

The efficacy of autologous platelet-rich plasma combined with erbium fractional laser therapy for facial acne scars or acne

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Abstract

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