|
1
|
Perkovic V, Agarwal R, Fioretto P,
Hemmelgarn BR, Levin A, Thomas MC, Wanner C, Kasiske BL, Wheeler DC
and Groop PH: Conference Participants: Management of patients with
diabetes and CKD: Conclusions from a ‘Kidney disease: Improving
global outcomes’ (KDIGO) controversies conference. Kidney Int.
90:1175–1183. 2016. View Article : Google Scholar
|
|
2
|
Kolset SO, Reinholt FP and Jenssen T:
Diabetic nephropathy and extracellular matrix. J Histochem
Cytochem. 60:976–986. 2012. View Article : Google Scholar :
|
|
3
|
Kanwar YS, Sun L, Xie P, Liu FY and Chen
S: A glimpse of various pathogenetic mechanisms of diabetic
nephropathy. Annu Rev Pathol. 6:395–423. 2011. View Article : Google Scholar :
|
|
4
|
Lan HY: Transforming growth factor-β/Smad
signalling in diabetic nephropathy. Clin Exp Pharmacol Physiol.
39:731–738. 2012. View Article : Google Scholar
|
|
5
|
Huang JS, Chuang LY, Guh JY, Chen CJ, Yang
YL, Chiang TA, Hung MY and Liao TN: Effect of nitric
oxide-cGMP-dependent protein kinase activation on advanced
glycation end-product-induced proliferation in renal fibroblasts. J
Am Soc Nephrol. 16:2318–2329. 2005. View Article : Google Scholar
|
|
6
|
Wu BN, Chen CW, Liou SF, Yeh JL, Chung HH
and Chen IJ: Inhibition of proinflammatory tumor necrosis
factor-{alpha}-induced inducible nitric-oxide synthase by
xanthine-based
7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine
(KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,
3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of
soluble guanylate cyclase and protein kinase G. Mol Pharmacol.
70:977–985. 2006. View Article : Google Scholar
|
|
7
|
Hong TY, Guh JY, Wu BN, Chai CY, Huang HT
and Chen IJ: KMUP-1 protects kidney from Streptozotocin-induced
proinflammation in early diabetic nephropathy by restoring
eNOS/PPARgamma and inhibiting MMP-9. European Journal of
Inflammation. 12:89–100. 2014. View Article : Google Scholar
|
|
8
|
Wu BN, Lin RJ, Lin CY, Shen KP, Chiang LC
and Chen IJ: A xanthine-based KMUP-1 with cyclic GMP enhancing and
K(+) channels opening activities in rat aortic smooth muscle. Br J
Pharmacol. 134:265–274. 2001. View Article : Google Scholar :
|
|
9
|
Lin RJ, Wu BN, Lo YC, Shen KP, Lin YT,
Huang CH and Chen IJ: KMUP-1 relaxes rabbit corpus cavernosum
smooth muscle in vitro and in vivo: Involvement of cyclic GMP and
K(+) channels. Br J Pharmacol. 135:1159–1166. 2002. View Article : Google Scholar :
|
|
10
|
Wu BN, Lin RJ, Lo YC, Shen KP, Wang CC,
Lin YT and Chen IJ: KMUP-1, a xanthine derivative, induces
relaxation of guinea-pig isolated trachea: The role of the
epithelium, cyclic nucleotides and K+ channels. Br J Pharmacol.
142:1105–1114. 2004. View Article : Google Scholar :
|
|
11
|
Michelson S, Alcami J, Kim SJ, Danielpour
D, Bachelerie F, Picard L, Bessia C, Paya C and Virelizier JL:
Human cytomegalovirus infection induces transcription and secretion
of transforming growth factor beta 1. J Virol. 68:5730–5737.
1994.
|
|
12
|
Wrana JL, Attisano L, Cárcamo J, Zentella
A, Doody J, Laiho M, Wang XF and Massagué J: TGF beta signals
through a heteromeric protein kinase receptor complex. Cell.
71:1003–1014. 1992. View Article : Google Scholar
|
|
13
|
Huang JS, Guh JY, Hung WC, Yang ML, Lai
YH, Chen HC and Chuang LY: Role of the Janus kinase (JAK)/signal
transducters and activators of transcription (STAT) cascade in
advanced glycation end-product-induced cellular mitogenesis in
NRK-49F cells. Biochem J. 342:231–238. 1999. View Article : Google Scholar :
|
|
14
|
Huang JS, Chuang LY, Guh JY, Huang YJ and
Hsu MS: Antioxidants attenuate high glucose-induced hypertrophic
growth in renal tubular epithelial cells. Am J Physiol Renal
Physiol. 293:F1072–F1082. 2007. View Article : Google Scholar
|
|
15
|
Shin SJ, Lai FJ, Wen JD, Hsiao PJ, Hsieh
MC, Tzeng TF, Chen HC, Guh JY and Tsai JH: Neuronal and endothelial
nitric oxide synthase expression in outer medulla of
streptozotocin-induced diabetic rat kidney. Diabetologia.
43:649–659. 2000. View Article : Google Scholar
|
|
16
|
Dai ZK, Lin TC, Liou JC, Cheng KI, Chen
JY, Chu LW, Chen IJ and Wu BN: Xanthine derivative KMUP-1 reduces
inflammation and hyperalgesia in a bilateral chronic constriction
injury model by suppressing MAPK and NFκB activation. Mol Pharm.
11:1621–1631. 2014. View Article : Google Scholar
|
|
17
|
Tsai CW: A Guidebook for the Care and Use
of Laboratory Animals. 3rd. Taiwan Council of Agriculture; Taipei,
Taiwan: 2010, (In Chinese).
|
|
18
|
Yano N, Suzuki D, Endoh M, Cao TN, Dahdah
JR, Tseng A, Stabila JP, McGonnigal BG, Padbury JF and Tseng YT:
High ambient glucose induces angiotensin-independent AT-1 receptor
activation, leading to increases in proliferation and extracellular
matrix accumulation in MES-13 mesangial cells. Biochem J.
423:129–143. 2009. View Article : Google Scholar
|
|
19
|
Jiang T, Che Q, Lin Y, Li H and Zhang N:
Aldose reductase regulates TGF-beta1-induced production of
fibronectin and type IV collagen in cultured rat mesangial cells.
Nephrology (Carlton). 11:105–112. 2006. View Article : Google Scholar
|
|
20
|
Yeh JL, Hsu JH, Wu PJ, Liou SF, Liu CP,
Chen IJ, Wu BN, Dai ZK and Wu JR: KMUP-1 attenuates
isoprenaline-induced cardiac hypertrophy in rats through
NO/cGMP/PKG and ERK1/2/calcineurin A pathways. Br J Pharmacol.
159:1151–1160. 2010. View Article : Google Scholar :
|
|
21
|
Goruppi S, Bonventre JV and Kyriakis JM:
Signaling pathways and late-onset gene induction associated with
renal mesangial cell hypertrophy. EMBO J. 21:5427–5436. 2002.
View Article : Google Scholar :
|
|
22
|
Tessari P: Nitric oxide in the normal
kidney and in patients with diabetic nephropathy. J Nephrol.
28:257–268. 2015. View Article : Google Scholar
|
|
23
|
Nakagawa T, Sato W, Glushakova O, Heinig
M, Clarke T, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Johnson RJ
and Croker B: Diabetic endothelial nitric oxide synthase knockout
mice develop advanced diabetic nephropathy. J Am Soc Nephrol.
18:539–550. 2007. View Article : Google Scholar
|
|
24
|
Stasch JP, Schlossmann J and Hocher B:
Renal effects of soluble guanylate cyclase stimulators and
activators: A review of the preclinical evidence. Curr Opin
Pharmacol. 21:95–104. 2015. View Article : Google Scholar
|
|
25
|
Reddy MA, Zhang E and Natarajan R:
Epigenetic mechanisms in diabetic complications and metabolic
memory. Diabetologia. 58:443–455. 2015. View Article : Google Scholar
|
|
26
|
Saura M, Zaragoza C, Herranz B, Griera M,
Diez-Marqués L, Rodriguez-Puyol D and Rodriguez-Puyol M: Nitric
oxide regulates transforming growth factor-beta signaling in
endothelial cells. Circ Res. 97:1115–1123. 2005. View Article : Google Scholar
|
|
27
|
Wang S, Shiva S, Poczatek MH, Darley-Usmar
V and Murphy-Ullrich JE: Nitric oxide and cGMP-dependent protein
kinase regulation of glucose-mediated thrombospondin 1-dependent
transforming growth factor-beta activation in mesangial cells. J
Biol Chem. 277:9880–9888. 2002. View Article : Google Scholar
|
|
28
|
Wang S, Wu X, Lincoln TM and
Murphy-Ullrich JE: Expression of constitutively active
cGMP-dependent protein kinase prevents glucose stimulation of
thrombospondin 1 expression and TGF-beta activity. Diabetes.
52:2144–2150. 2003. View Article : Google Scholar
|
|
29
|
Ott IM, Alter ML, von Websky K, Kretschmer
A, Tsuprykov O, Sharkovska Y, Krause-Relle K, Raila J, Henze A,
Stasch JP and Hocher B: Effects of stimulation of soluble guanylate
cyclase on diabetic nephropathy in diabetic eNOS knockout mice on
top of angiotensin II receptor blockade. PLoS One. 7:e426232012.
View Article : Google Scholar :
|
|
30
|
Villeneuve LM, Reddy MA, Lanting LL, Wang
M, Meng L and Natarajan R: Epigenetic histone H3 lysine 9
methylation in metabolic memory and inflammatory phenotype of
vascular smooth muscle cells in diabetes. Proc Natl Acad Sci USA.
105:pp. 9047–9052. 2008; View Article : Google Scholar :
|
|
31
|
Reddy MA, Sumanth P, Lanting L, Yuan H,
Wang M, Mar D, Alpers CE, Bomsztyk K and Natarajan R: Losartan
reverses permissive epigenetic changes in renal glomeruli of
diabetic db/db mice. Kidney Int. 85:362–373. 2014. View Article : Google Scholar
|
|
32
|
Yang B, Yang J, Bai J, Pu P, Liu J, Wang F
and Ruan B: Suv39h1 protects from myocardial ischemia-reperfusion
injury in diabetic rats. Cell Physiol Biochem. 33:1176–1185. 2014.
View Article : Google Scholar
|
|
33
|
Wu L and Derynck R: Essential role of
TGF-beta signaling in glucose-induced cell hypertrophy. Dev Cell.
17:35–48. 2009. View Article : Google Scholar :
|
|
34
|
Williams JM, Zhang J, North P, Lacy S,
Yakes M, Dahly-Vernon A and Roman RJ: Evaluation of metalloprotease
inhibitors on hypertension and diabetic nephropathy. Am J Physiol
Renal Physiol. 300:F983–F998. 2011. View Article : Google Scholar :
|
