Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Molecular Medicine Reports
Join Editorial Board Propose a Special Issue
Print ISSN: 1791-2997 Online ISSN: 1791-3004
Journal Cover
August-2017 Volume 16 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2017 Volume 16 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review

Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review)

  • Authors:
    • Zhu‑Jun Yi
    • Jian‑Ping Gong
    • Wei Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, Sichuan 400010, P.R. China, Department of Hepatobiliary Surgery, The People's Hospital of Jianyang, Jianyang, Sichuan 641400, P.R. China
  • Pages: 994-1000
    |
    Published online on: June 2, 2017
       https://doi.org/10.3892/mmr.2017.6683
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The inflammatory response is a physiological process that is essential for maintaining homeostasis of the immune system. Inflammation is classified into acute inflammation and chronic inflammation, both of which pose a risk to human health. However, specific regulatory mechanisms of the inflammatory response remain to be elucidated. Receptor interacting protein (RIP) 140 is a nuclear receptor that affects an extensive array of biological and pathological processes in the body, including energy metabolism, inflammation and tumorigenesis. RIP140‑mediated macrophage polarization is important in regulating the inflammatory response. Overexpression of RIP140 in macrophages results in M1‑like polarization and expansion during the inflammatory response. Conversely, decreased expression of RIP140 in macrophages reduces the number of M1‑like macrophages and increases the number of alternatively polarized cells, which collectively promote endotoxin tolerance (ET) and relieve inflammation. This review summarizes the role of RIP140 in acute and chronic inflammatory diseases, with a focus on insulin resistance, atherosclerosis, sepsis and ET.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Rosell M, Jones MC and Parker MG: Role of nuclear receptor corepressor RIP140 in metabolic syndrome. Biochim Biophys Acta. 1812:919–928. 2011. View Article : Google Scholar : PubMed/NCBI

2 

White R, Morganstein D, Christian M, Seth A, Herzog B and Parker MG: Role of RIP140 in metabolic tissues: Connections to disease. FEBS Lett. 582:39–45. 2008. View Article : Google Scholar : PubMed/NCBI

3 

Fritah A, Christian M and Parker MG: The metabolic coregulator RIP140: An update. Am J Physiol Endocrinol Metab. 299:E335–E340. 2010. View Article : Google Scholar : PubMed/NCBI

4 

Chung HT: RIP140, a Janus metabolic switch involved in defense functions. Cell Mol Immunol. 10:7–9. 2013. View Article : Google Scholar : PubMed/NCBI

5 

Ho PC, Chuang YS, Hung CH and Wei LN: Cytoplasmic receptor-interacting protein 140 (RIP140) interacts with perilipin to regulate lipolysis. Cell Signal. 23:1396–1403. 2011. View Article : Google Scholar : PubMed/NCBI

6 

Powelka AM, Seth A, Virbasius JV, Kiskinis E, Nicoloro SM, Guilherme A, Tang X, Straubhaar J, Cherniack AD, Parker MG and Czech MP: Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. J Clin Invest. 116:125–136. 2006. View Article : Google Scholar : PubMed/NCBI

7 

Docquier A, Harmand PO, Fritsch S, Chanrion M, Darbon JM and Cavaillès V: The transcriptional coregulator RIP140 represses E2F1 activity and discriminates breast cancer subtypes. Clin Cancer Res. 16:2959–2970. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Lapierre M, Bonnet S, Bascoul-Mollevi C, Ait-Arsa I, Jalaguier S, Del Rio M, Plateroti M, Roepman P, Ychou M, Pannequin J, et al: RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis. J Clin Invest. 124:1899–1913. 2014. View Article : Google Scholar : PubMed/NCBI

9 

Zhang D, Wang Y, Dai Y, Wang J, Suo T, Pan H and Liu H, Shen S and Liu H: Downregulation of RIP140 in hepatocellular carcinoma promoted the growth and migration of the cancer cells. Tumour Biol. 36:2077–2085. 2015. View Article : Google Scholar : PubMed/NCBI

10 

Zschiedrich I, Hardeland U, Krones-Herzig A, Diaz M Berriel, Vegiopoulos A, Müggenburg J, Sombroek D, Hofmann TG, Zawatzky R, Yu X, et al: Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression. Blood. 112:264–276. 2008. View Article : Google Scholar : PubMed/NCBI

11 

Ho PC, Tsui YC, Feng X, Greaves DR and Wei LN: NF-kB-mediated degradation of the co-activator RIP140 regulates inflammatory response and contributes to endotoxin tolerance. Nat Immunol. 13:379–386. 2012. View Article : Google Scholar : PubMed/NCBI

12 

Kopanakis K, Tzepi IM, Pistiki A, Carrer DP, Netea MG, Georgitsi M, Lymperi M, Droggiti DI, Liakakos T, Machairas A and Giamarellos-Bourboulis EJ: Pre-treatment with low-dose endotoxin prolongs survival from experimental lethal endotoxic shock: Benefit for lethal peritonitis by Escherichia coli. Cytokine. 62:382–388. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Guilherme A, Virbasius JV, Puri V and Czech MP: Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol. 9:367–377. 2008. View Article : Google Scholar : PubMed/NCBI

14 

Jiang X, Huang L and Xing D: Photoactivation of Dok1/ERK/PPARγ signaling axis inhibits excessive lipolysis in insulin-resistant adipocytes. Cell Signal. 27:1265–1275. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Kelley DE, Mokan M, Simoneau JA and Mandarino LJ: Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest. 92:91–98. 1993. View Article : Google Scholar : PubMed/NCBI

16 

Barma P and Bhattacharya S, Bhattacharya A, Kundu R, Dasgupta S, Biswas A and Bhattacharya S, Roy SS and Bhattacharya S: Lipid induced overexpression of NF-kappaB in skeletal muscle cells is linked to insulin resistance. Biochim Biophys Acta. 1792:190–200. 2009. View Article : Google Scholar : PubMed/NCBI

17 

Unger RH: Lipotoxic diseases. Annu Rev Med. 53:319–336. 2002. View Article : Google Scholar : PubMed/NCBI

18 

Santomauro AT, Boden G, Silva ME, Rocha DM, Santos RF, Ursich MJ, Strassmann PG and Wajchenberg BL: Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes. 48:1836–1841. 1999. View Article : Google Scholar : PubMed/NCBI

19 

Savage DB, Petersen KF and Shulman GI: Disordered lipid metabolism and the pathogenesis of insulin resistance. Physiol Rev. 87:507–520. 2007. View Article : Google Scholar : PubMed/NCBI

20 

Christianson JL, Nicoloro S, Straubhaar J and Czech MP: Stearoyl-CoA desaturase 2 is required for peroxisome proliferator-activated receptor gamma expression and adipogenesis in cultured 3T3-L1 cells. J Biol Chem. 283:2906–2916. 2008. View Article : Google Scholar : PubMed/NCBI

21 

Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL and Ferrante AW Jr: Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 112:1796–1808. 2003. View Article : Google Scholar : PubMed/NCBI

22 

Liu PS, Lin YW, Burton FH and Wei LN: M1-M2 balancing act in white adipose tissue browning-a new role for RIP140. Adipocyte. 4:146–148. 2015. View Article : Google Scholar : PubMed/NCBI

23 

Liu PS, Lin YW, Lee B, McCrady-Spitzer SK, Levine JA and Wei LN: Reducing RIP140 expression in macrophage alters ATM infiltration, facilitates white adipose tissue browning, and prevents high-fat diet-induced insulin resistance. Diabetes. 63:4021–4031. 2014. View Article : Google Scholar : PubMed/NCBI

24 

Cancello R, Henegar C, Viguerie N, Taleb S, Poitou C, Rouault C, Coupaye M, Pelloux V, Hugol D, Bouillot JL, et al: Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes. 54:2277–2786. 2005. View Article : Google Scholar : PubMed/NCBI

25 

Sartipy P and Loskutoff DJ: Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci USA. 100:7265–7270. 2003. View Article : Google Scholar : PubMed/NCBI

26 

Rull A, Camps J, Alonso-Villaverde C and Joven J: Insulin resistance, inflammation, and obesity: Role of monocyte chemoattractant protein-1 (or CCL2) in the regulation of metabolism. Mediators Inflamm. 2010:pii: 3265802010. View Article : Google Scholar

27 

Uchida Y, Takeshita K, Yamamoto K, Kikuchi R, Nakayama T, Nomura M, Cheng XW, Egashira K, Matsushita T, Nakamura H and Murohara T: Stress augments insulin resistance and prothrombotic state: Role of visceral adipose-derived monocyte chemoattractant protein-1. Diabetes. 61:1552–1561. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM and Karin M: JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab. 6:386–397. 2007. View Article : Google Scholar : PubMed/NCBI

29 

Tang X, Guilherme A, Chakladar A, Powelka AM, Konda S, Virbasius JV, Nicoloro SM, Straubhaar J and Czech MP: An RNA interference-based screen identifies MAP4K4/NIK as a negative regulator of PPAR gamma, adipogenesis, and insulin-responsive hexose transport. Proc Natl Acad Sci USA. 103:2087–2092. 2006. View Article : Google Scholar : PubMed/NCBI

30 

Shulman GI: Cellular mechanisms of insulin resistance. J Clin Invest. 106:171–176. 2000. View Article : Google Scholar : PubMed/NCBI

31 

Tesz GJ, Guilherme A, Guntur KV, Hubbard AC, Tang X, Chawla A and Czech MP: Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. J Biol Chem. 282:19302–19312. 2007. View Article : Google Scholar : PubMed/NCBI

32 

Hotamisligil GS, Shargill NS and Spiegelman BM: Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science. 259:87–91. 1993. View Article : Google Scholar : PubMed/NCBI

33 

Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW and Chawla A: Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature. 447:1116–1120. 2007. View Article : Google Scholar : PubMed/NCBI

34 

Yamaguchi Y, Cavallero S, Patterson M, Shen H, Xu J, Kumar SR and Sucov HM: Adipogenesis and epicardial adipose tissue: A novel fate of the epicardium induced by mesenchymal transformation and PPARγ activation. Proc Natl Acad Sci USA. 112:2070–2075. 2015. View Article : Google Scholar : PubMed/NCBI

35 

Imai T, Takakuwa R, Marchand S, Dentz E, Bornert JM, Messaddeq N, Wendling O, Mark M, Desvergne B, Wahli W, et al: Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci USA. 101:4543–4547. 2004. View Article : Google Scholar : PubMed/NCBI

36 

Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, et al: Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers. Genes Dev. 29:7–22. 2015. View Article : Google Scholar : PubMed/NCBI

37 

Siersbæk MS, Loft A, Aagaard MM, Nielsen R, Schmidt SF, Petrovic N, Nedergaard J and Mandrup S: Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression. Mol Cell Biol. 32:3452–3463. 2012. View Article : Google Scholar : PubMed/NCBI

38 

Ait-Lounis A and Laraba-Djebari F: TNF-alpha modulates adipose macrophage polarization to M1 phenotype in response to scorpion venom. Inflamm Res. 64:929–936. 2015. View Article : Google Scholar : PubMed/NCBI

39 

Bing C: Is interleukin-1β a culprit in macrophage-adipocyte cross talk in obesity? Adipocyte. 4:149–152. 2015. View Article : Google Scholar : PubMed/NCBI

40 

McLaren JE, Michael DR, Ashlin TG and Ramji DP: Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy. Prog Lipid Res. 50:331–347. 2011. View Article : Google Scholar : PubMed/NCBI

41 

Qiu Y, Yanase T, Hu H, Tanaka T, Nishi Y, Liu M, Sueishi K, Sawamura T and Nawata H: Dihydrotestosterone suppresses foam cell formation and attenuates atherosclerosis development. Endocrinology. 151:3307–3316. 2010. View Article : Google Scholar : PubMed/NCBI

42 

Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C and Tall AR: Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. J Clin Invest. 117:3900–3908. 2007.PubMed/NCBI

43 

Wei H, Tarling EJ, McMillen TS, Tang C and LeBoeuf RC: ABCG1 regulates mouse adipose tissue macrophage cholesterol levels and the ratio of M1 to M2 cells during obesity and caloric restriction. J Lipid Res. 56:2337–2347. 2015. View Article : Google Scholar : PubMed/NCBI

44 

Lin YW, Liu PS, Adhikari N, Hall JL and Wei LN: RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages. J Mol Cell Cardiol. 79:287–294. 2015. View Article : Google Scholar : PubMed/NCBI

45 

Dawson MI and Xia Z: The retinoid X receptors and their ligands. Biochim Biophys Acta. 1821:21–56. 2012. View Article : Google Scholar : PubMed/NCBI

46 

Calkin AC and Tontonoz P: Liver X receptor signaling pathways and atherosclerosis. Arterioscler Thromb Vasc Biol. 30:1513–1518. 2010. View Article : Google Scholar : PubMed/NCBI

47 

He Y, Zhang L, Li Z, Gao H, Yue Z, Liu Z, Liu X, Feng X and Liu P: RIP140 triggers foam-cell formation by repressing ABCA1/G1 expression and cholesterol efflux via liver X receptor. FEBS Lett. 589:455–460. 2015. View Article : Google Scholar : PubMed/NCBI

48 

Calkin AC and Tontonoz P: Transcriptional integration of metabolism by the nuclear sterol-activated receptors lXR and FXR. Nat Rev Mol Cell Biol. 13:213–224. 2012.PubMed/NCBI

49 

Ho PC, Chang KC, Chuang YS and Wei LN: Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production. FASEB J. 25:1758–1766. 2011. View Article : Google Scholar : PubMed/NCBI

50 

Rayner KJ, Sheedy FJ, Esau CC, Hussain FN, Temel RE, Parathath S, van Gils JM, Rayner AJ, Chang AN, Suarez Y, et al: Antagonism of mir-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J Clin Invest. 121:2921–2931. 2011. View Article : Google Scholar : PubMed/NCBI

51 

Dávalos A and Fernández-Hernando C: From evolution to revolution: miRNAs as pharmacological targets for modulating cholesterol efflux and reverse cholesterol transport. Pharmacol Res. 75:60–72. 2013. View Article : Google Scholar : PubMed/NCBI

52 

Karasawa T and Takahashi M: RIP140 as a novel therapeutic target in the treatment of atherosclerosis. J Mol Cell Cardiol. 81:136–138. 2015. View Article : Google Scholar : PubMed/NCBI

53 

Jawad I, Lukšić I and Rafnsson SB: Assessing available information on the burden of sepsis: Global estimates of incidence, prevalence and mortality. J Glob Health. 2:0104042012. View Article : Google Scholar : PubMed/NCBI

54 

Charchaflieh J, Wei J, Labaze G, Hou YJ, Babarsh B, Stutz H, Lee H, Worah S and Zhang M: The role of complement system in septic shock. Clin Dev Immunol. 2012:4073242012. View Article : Google Scholar : PubMed/NCBI

55 

Wang X and Quinn PJ: Lipopolysaccharide: Biosynthetic pathway and structure modification. Prog Lipid Res. 49:97–107. 2010. View Article : Google Scholar : PubMed/NCBI

56 

Xiong Y, Pennini M, Vogel SN and Medvedev AE: IRAK4 kinase activity is not required for induction of endotoxin tolerance but contributes to TLR2-mediated tolerance. J Leukoc Biol. 94:291–300. 2013. View Article : Google Scholar : PubMed/NCBI

57 

Laird MH, Rhee SH, Perkins DJ, Medvedev AE, Piao W, Fenton MJ and Vogel SN: TLR4/MyD88/PI3K interactions regulate TLR4 signaling. J Leukoc Biol. 85:966–977. 2009. View Article : Google Scholar : PubMed/NCBI

58 

Nahid MA, Satoh M and Chan EK: MicroRNA in TLR signaling and endotoxin tolerance. Cell Mol Immunol. 8:388–403. 2011. View Article : Google Scholar : PubMed/NCBI

59 

Liew FY, Xu D, Brint EK and O'Neill LA: Negative regulation of Toll-like receptor-mediated immune responses. Nat Rev Immunol. 5:446–458. 2005. View Article : Google Scholar : PubMed/NCBI

60 

Park SH, Park-Min KH, Chen J, Hu X and Ivashkiv LB: Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages. Nat Immunol. 12:607–615. 2011. View Article : Google Scholar : PubMed/NCBI

61 

Chen J and Ivashkiv LB: IFN-γ abrogates endotoxin tolerance by facilitating Toll-like receptor induced chromatin remodeling. Proc Natl Acad Sci USA. 107:19438–19443. 2010. View Article : Google Scholar : PubMed/NCBI

62 

Chen Y, Liu Z, Liang S, Luan X, Long F, Chen J, Peng Y, Yan L and Gong J: Role of Kupffer cells in the induction of tolerance of orthotopic liver transplantation in rats. Liver Transpl. 14:823–836. 2008. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Yi ZJ, Gong JP and Zhang W: Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review). Mol Med Rep 16: 994-1000, 2017.
APA
Yi, Z., Gong, J., & Zhang, W. (2017). Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review). Molecular Medicine Reports, 16, 994-1000. https://doi.org/10.3892/mmr.2017.6683
MLA
Yi, Z., Gong, J., Zhang, W."Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review)". Molecular Medicine Reports 16.2 (2017): 994-1000.
Chicago
Yi, Z., Gong, J., Zhang, W."Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review)". Molecular Medicine Reports 16, no. 2 (2017): 994-1000. https://doi.org/10.3892/mmr.2017.6683
Copy and paste a formatted citation
x
Spandidos Publications style
Yi ZJ, Gong JP and Zhang W: Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review). Mol Med Rep 16: 994-1000, 2017.
APA
Yi, Z., Gong, J., & Zhang, W. (2017). Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review). Molecular Medicine Reports, 16, 994-1000. https://doi.org/10.3892/mmr.2017.6683
MLA
Yi, Z., Gong, J., Zhang, W."Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review)". Molecular Medicine Reports 16.2 (2017): 994-1000.
Chicago
Yi, Z., Gong, J., Zhang, W."Transcriptional co-regulator RIP140: An important mediator of the inflammatory response and its associated diseases (Review)". Molecular Medicine Reports 16, no. 2 (2017): 994-1000. https://doi.org/10.3892/mmr.2017.6683
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team