|
1
|
Querfurth HW and LaFerla FM: Alzheimer's
disease. N Engl J Med. 362:329–344. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Brookmeyer R, Johnson E, Ziegler-Graham K
and Arrighi HM: Forecasting the global burden of Alzheimer's
disease. Alzheimers Dement. 3:186–191. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ballard C, Gauthier S, Corbett A, Brayne
C, Aarsland D and Jones E: Alzheimer's disease. Lancet.
377:1019–1031. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Gandy S and DeKosky ST: Toward the
treatment and prevention of Alzheimer's disease: Rational
strategies and recent progress. Annu Rev Med. 64:367–383. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Mattson MP: Apoptosis in neurodegenerative
disorders. Nat Rev Mol Cell Biol. 1:120–129. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Morishima Y, Gotoh Y, Zieg J, Barrett T,
Takano H, Flavell R, Davis RJ, Shirasaki Y and Greenberg ME:
Beta-amyloid induces neuronal apoptosis via a mechanism that
involves the c-Jun N-terminal kinase pathway and the induction of
Fas ligand. J Neurosci. 21:7551–7560. 2001.PubMed/NCBI
|
|
7
|
Favaloro B, Allocati N, Graziano V, Di
Ilio C and De Laurenzi V: Role of apoptosis in disease. Aging
(Albany NY). 4:330–349. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Muradian K and Schachtschabel DO: The role
of apoptosis in aging and age-related disease: Update. Z Gerontol
Geriatr. 34:441–446. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
He H, Dong W and Huang F:
Anti-amyloidogenic and anti-apoptotic role of melatonin in
Alzheimer disease. Curr Neuropharmacol. 8:211–227. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tait SW and Green DR: Mitochondria and
cell death: Outer membrane permeabilization and beyond. Nat Rev Mol
Cell Biol. 11:621–632. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
11
|
Dai Y, Zhang W, Sun Q, Zhang X, Zhou X, Hu
Y and Shi J: Nuclear receptor nur77 promotes cerebral cell
apoptosis and induces early brain injury after experimental
subarachnoid hemorrhage in rats. J Neurosci Res. 92:1110–1121.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Moll UM, Marchenko N and Zhang XK: p53 and
Nur77/TR3-transcription factors that directly target mitochondria
for cell death induction. Oncogene. 25:4725–4743. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Lin B, Kolluri SK, Lin F, Liu W, Han YH,
Cao X, Dawson MI, Reed JC and Zhang XK: Conversion of Bcl-2 from
protector to killer by interaction with nuclear orphan receptor
Nur77/TR3. Cell. 116:527–540. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lin XF, Zhao BX, Chen HZ, Ye XF, Yang CY,
Zhou HY, Zhang MQ, Lin SC and Wu Q: RXR alpha acts as a carrier for
TR3 nuclear export in a 9-cis retinoic acid-dependent manner in
gastric cancer cells. J Cell Sci. 117:5609–5621. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhang XK, Su Y, Chen L, Chen F, Liu J and
Zhou H: Regulation of the nongenomic actions of retinoid X
receptor-α by targeting the coregulator-binding sites. Acta
Pharmacol Sin. 36:102–112. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Salerno AJ, He Z, Goos-Nilsson A, Ahola H
and Mak P: Differential transcriptional regulation of the apoAI
gene by retinoic acid receptor homo- and heterodimers in yeast.
Nucleic Acids Res. 24:566–572. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lefebvre P, Benomar Y and Staels B:
Retinoid X receptors: Common heterodimerization partners with
distinct functions. Trends Endocrinol Metab. 21:676–683. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Cao X, Liu W, Lin F, Li H, Kolluri SK, Lin
B, Han YH, Dawson MI and Zhang XK: Retinoid X receptor regulates
Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear
export and mitochondrial targeting. Mol Cell Biol. 24:9705–9725.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Akram A, Schmeidler J, Katsel P, Hof PR
and Haroutunian V: Increased expression of RXRα in dementia: A
nearly harbinger for the cholesterol dyshomeostasis? Mol
Neurodegener. 5:362010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Kiss B, Tóth K, Sarang Z, Garabuczi É and
Szondy Z: Retinoids induce Nur77-dependent apoptosis in mouse
thymocytes. Biochim Biophys Acta. 1853:660–670. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cunningham NR, Artim SC, Fornadel CM,
Sellars MC, Edmonson SG, Scott G, Albino F, Mathur A and Punt JA:
Immature CD4+CD8+ thymocytes and mature T
cells regulate Nur77 distinctly in response to TCR stimulation. J
Immunol. 177:6660–6666. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wu Q, Liu S, Ye XF, Huang ZW and Su WJ:
Dual roles of Nur77 in selective regulation of apoptosis and cell
cycle by TPA and ATRA in gastric cancer cells. Carcinogenesis.
23:1583–1592. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Yu H, Kumar SM, Fang D, Acs G and Xu X:
Nuclear orphan receptor TR3/Nur77 mediates melanoma cell apoptosis.
Cancer Biol Ther. 6:405–412. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Suzuki S, Suzuki N, Mirtsos C, Horacek T,
Lye E, Noh SK, Ho A, Bouchard D, Mak TW and Yeh WC: Nur77 as a
survival factor in tumor necrosis factor signaling. Proc Natl Acad
Sci USA. 100:8276–8280. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
You X, Zhang YW, Chen Y, Huang X, Xu R,
Cao X, Chen J, Liu Y, Zhang X and Xu H: Retinoid X receptor-alpha
mediates (R)-flurbiprofen's effect on the levels of Alzheimer's
beta-amyloid. J Neurochem. 111:142–149. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Gillies LA and Kuwana T: Apoptosis
regulation at the mitochondrial outer membrane. J Cell Biochem.
115:632–640. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Haass C and Selkoe DJ: Soluble protein
oligomers in neurodegeneration: Lessons from the Alzheimer's
amyloid beta-peptide. Nat Rev Mol Cell Biol. 8:101–112. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Watson D, Castaño E, Kokjohn TA, Kuo YM,
Lyubchenko Y, Pinsky D, Connolly ES Jr, Esh C, Luehrs DC, Stine WB,
et al: Physicochemical characteristics of soluble oligomeric Abeta
and their pathologic role in Alzheimer's disease. Neurol Res.
27:869–881. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Mucke L and Selkoe DL: Neurotoxicity of
amyloid β-protein: synaptic and network dysfunction. Cold Spring
Harb Perspect Med. 2:a0063382012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Basu A and Haldar S: The relationship
between BcI2, Bax and p53: Consequences for cell cycle progression
and cell death. Mol Hum Reprod. 4:1099–1109. 1998. View Article : Google Scholar : PubMed/NCBI
|
