|
1
|
Ogawa A, Yamadori I, Matsubara O and
Matsubara H: Pulmonary tumor thrombotic microangiopathy with
circulatory failure treated with imatinib. Intern Med.
52:1927–1930. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Afonso AS, Verhamme KM, Sturkenboom MC and
Brusselle GG: COPD in the general population: Prevalence, incidence
and survival. Respir Med. 105:1872–1884. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Csiszar A, Labinskyy N, Olson S, Pinto JT,
Gupte S, Wu JM, Hu F, Ballabh P, Podlutsky A, Losonczy G, et al:
Resveratrol prevents monocrotaline-induced pulmonary hypertension
in rats. Hypertension. 54:668–675. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
He X, Wang Y, Zhu J, Orloff M and Eng C:
Resveratrol enhances the anti-tumor activity of the mTOR inhibitor
rapamycin in multiple breast cancer cell lines mainly by
suppressing rapamycin-induced AKT signaling. Cancer Lett.
301:168–176. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ji Q, Liu X, Fu X, Zhang L, Sui H, Zhou L,
Sun J, Cai J, Qin J, Ren J and Li Q: Resveratrol inhibits invasion
and metastasis of colorectal cancer cells via MALAT1 mediated
Wnt/β-catenin signal pathway. PLoS One. 8:e787002013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Soto BL, Hank JA, Van de Voort TJ,
Subramanian L, Polans AS, Rakhmilevich AL, Yang RK, Seo S, Kim K,
Reisfeld RA, et al: The anti-tumor effect of resveratrol alone or
in combination with immunotherapy in a neuroblastoma model. Cancer
Immunology Immunotherapy. 60:731–738. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Brody H: Chronic obstructive pulmonary
disease. Nature. 489:S12012. View
Article : Google Scholar : PubMed/NCBI
|
|
8
|
Torpy JM, Goodman DM, Burke AE and
Livingston EH: JAMA patient page. CHronic obstructive pulmonary
disease. JAMA. 308:12812012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Tuder RM and Petrache I: Pathogenesis of
chronic obstructive pulmonary disease. J Clin Invest.
122:2749–2755. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lahm T, Albrecht M, Fisher AJ, Selej M,
Patel NG, Brown JA, Justice MJ, Brown MB, van Demark M, Trulock KM,
et al: 17β-Estradiol attenuates hypoxic pulmonary hypertension via
estrogen receptor-mediated effects. Am J Respir Crit Care Med.
185:965–980. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Lee SJ, Smith A, Guo L, Alastalo TP, Li M,
Sawada H, Liu X, Chen ZH, Ifedigbo E, Jin Y, et al: Autophagic
protein LC3B confers resistance against hypoxia-induced pulmonary
hypertension. Am J Respir Crit Care Med. 183:649–658. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Testa JR and Bellacosa A: AKT plays a
central role in tumorigenesis. Proc Natl Acad Sci USA.
98:10983–10985. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Sexton E, van Themsche C, LeBlanc K,
Parent S, Lemoine P and Asselin E: Resveratrol interferes with AKT
activity and triggers apoptosis in human uterine cancer cells. Mol
Cancer. 5:452006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Jiang H, Shang X, Wu H, Gautam SC,
Al-Holou S, Li C, Kuo J, Zhang L and Chopp M: Resveratrol
downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma
cells. J Exp Ther Oncol. 8:25–33. 2009.PubMed/NCBI
|
|
15
|
Wu J, Yu Z and Su D: BMP4 protects rat
pulmonary arterial smooth muscle cells from apoptosis by
PI3K/AKT/Smad1/5/8 signaling. Int J Mol Sci. 15:13738–13754. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yi B, Cui J, Ning JN, Wang GS, Qian GS and
Lu KZ: Over-expression of PKGIα inhibits hypoxia-induced
proliferation, Akt activation, and phenotype modulation of human
PASMCs: The role of phenotype modulation of PASMCs in pulmonary
vascular remodeling. Gene. 492:354–360. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Alexander MR and Owens GK: Epigenetic
control of smooth muscle cell differentiation and phenotypic
switching in vascular development and disease. Annu Rev Physiol.
74:13–40. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Deng L, Blanco FJ, Stevens H, Lu R,
Caudrillier A, McBride M, McClure JD, Grant J, Thomas M, Frid M, et
al: MicroRNA-143 activation regulates smooth muscle and endothelial
cell crosstalk in pulmonary arterial hypertension. Circ Res.
117:870–883. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lu A, Zuo C, He Y, Chen G, Piao L, Zhang
J, Xiao B, Shen Y, Tang J, Kong D, et al: EP3 receptor deficiency
attenuates pulmonary hypertension through suppression of Rho/TGF-β1
signaling. J Clin Invest. 125:1228–1242. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wallerath T, Deckert G, Ternes T, Anderson
H, Li H, Witte K and Förstermann U: Resveratrol, a polyphenolic
phytoalexin present in red wine, enhances expression and activity
of endothelial nitric oxide synthase. Circulation. 106:1652–1658.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Jimenez-Gomez Y, Mattison JA, Pearson KJ,
Martin-Montalvo A, Palacios HH, Sossong AM, Ward TM, Younts CM,
Lewis K, Allard JS, et al: Resveratrol improves adipose insulin
signaling and reduces the inflammatory response in adipose tissue
of rhesus monkeys on high-fat, high-sugar diet. Cell Metab.
18:533–545. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Andreadi C, Britton RG, Patel KR and Brown
K: Resveratrol-sulfates provide an intracellular reservoir for
generation of parent resveratrol, which induces autophagy in cancer
cells. Autophagy. 10:524–525. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Mattison JA, Wang M, Bernier M, Zhang J,
Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, et
al: Resveratrol prevents high fat/sucrose diet-induced central
arterial wall inflammation and stiffening in nonhuman primates.
Cell Metab. 20:183–190. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Chicoine LG, Stewart JA Jr and Lucchesi
PA: Is resveratrol the magic bullet for pulmonary hypertension?
Hypertension. 54:473–474. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Yang DL, Zhang HG, Xu YL, Gao YH, Yang XJ,
Hao XQ and Li XH: Resveratrol inhibits right ventricular
hypertrophy induced by monocrotaline in rats. Clin Exp Pharmacol
Physiol. 37:150–155. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Paffett ML, Lucas SN and Campen MJ:
Resveratrol reverses monocrotaline-induced pulmonary vascular and
cardiac dysfunction: A potential role for atrogin-1 in smooth
muscle. Vascul Pharmacol. 56:64–73. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Huang Z, Wang L, Chen L, Zhang Y and Shi
P: Induction of cell cycle arrest via the p21, p27-cyclin E, A/Cdk2
pathway in SMMC-7721 hepatoma cells by clioquinol. Acta Pharm.
65:463–471. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Yadav V, Sultana S, Yadav J and Saini N:
Gatifloxacin induces S and G2-phase cell cycle arrest in pancreatic
cancer cells via p21/p27/p53. PLoS One. 7:e477962012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Shivakrupa R, Bernstein A, Watring N and
Linnekin D: Phosphatidylinositol 3′-kinase is required for growth
of mast cells expressing the kit catalytic domain mutant. Cancer
Res. 63:4412–4419. 2003.PubMed/NCBI
|
|
30
|
Roche S, Koegl M and Courtneidge SA: The
phosphatidylinositol 3-kinase alpha is required for DNA synthesis
induced by some, but not all, growth factors. Proc Natl Acad Sci
USA. 91:9185–9189. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Alessi DR, Andjelkovic M, Caudwell B, Cron
P, Morrice N, Cohen P and Hemmings BA: Mechanism of activation of
protein kinase B by insulin and IGF-1. EMBO J. 15:6541–6551.
1996.PubMed/NCBI
|
|
32
|
Rachid O and Alkhalaf M: Resveratrol
Regulation of PI3K-AKT Signaling Pathway Genes in MDA-MB-231 Breast
Cancer Cells. Cancer Genomics Proteomics. 3:383–388. 2006.
|
|
33
|
Chen B, Xue J, Meng X, Slutzky JL, Calvert
AE and Chicoine LG: Resveratrol prevents hypoxia-induced arginase
II expression and proliferation of human pulmonary artery smooth
muscle cells via Akt-dependent signaling. Am J Physiol Lung Cell
Mol Physiol. 307:L317–L325. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Goncharova EA, Ammit AJ, Irani C, Carroll
RG, Eszterhas AJ, Panettieri RA and Krymskaya VP: PI3K is required
for proliferation and migration of human pulmonary vascular smooth
muscle cells. Am J Physiol Lung Cell Mol Physiol. 283:L354–L363.
2002. View Article : Google Scholar : PubMed/NCBI
|
