1
|
Cookson WO and Moffatt MF: Bedside to gene
and back in idiopathic pulmonary fibrosis. N Engl J Med.
368:2228–2230. 2013. View Article : Google Scholar : PubMed/NCBI
|
2
|
Fernandez IE and Eickelberg O: New
cellular and molecular mechanisms of lung injury and fibrosis in
idiopathic pulmonary fibrosis. Lancet. 380:680–688. 2012.
View Article : Google Scholar : PubMed/NCBI
|
3
|
Puglisi S, Torrisi S, Giuliano R, Vindigni
V and Vancheri C: What we know about the pathogenesis of idiopathic
pulmonary fibrosis. Semin Respir Crit Care Med. 37:358–367. 2016.
View Article : Google Scholar : PubMed/NCBI
|
4
|
King TE, Pardo A and Selman M: Idiopathic
pulmonary fibrosis. Lancet. 378:1949–1961. 2011. View Article : Google Scholar : PubMed/NCBI
|
5
|
Sun H, Chen J, Qian W, Kang J, Wang J,
Jiang L, Qiao L, Chen W and Zhang J: Integrated long non-coding RNA
analyses identify novel regulators of epithelial-mesenchymal
transition in the mouse model of pulmonary fibrosis. J Cell Mol
Med. 20:1234–1246. 2016. View Article : Google Scholar : PubMed/NCBI
|
6
|
Puvvula PK, Desetty RD, Pineau P, Marchio
A, Moon A, Dejean A and Bischof O: Long noncoding RNA PANDA and
scaffold-attachment-factor SAFA control senescence entry and exit.
Nat Commun. 5:53232014. View Article : Google Scholar : PubMed/NCBI
|
7
|
Szafranski K, Abraham KJ and Mekhail K:
Non-coding RNA in neural function, disease and aging. Front Genet.
6:872015. View Article : Google Scholar : PubMed/NCBI
|
8
|
Magnuson B, Ekim B and Fingar DC:
Regulation and function of ribosomal protein S6 kinase (S6K) within
mTOR signalling networks. Biochem J. 441:1–21. 2012. View Article : Google Scholar : PubMed/NCBI
|
9
|
Selman C, Tullet JM, Wieser D, Irvine E,
Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D,
Ramadani F, et al: Ribosomal protein S6 kinase 1 signaling
regulates mammalian life span. Science. 326:140–144. 2009.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Sharp ZD: Aging and TOR: Interwoven in the
fabric of life. Cell Mol Life Sci. 68:587–597. 2011. View Article : Google Scholar : PubMed/NCBI
|
11
|
Katakura Y, Nakata E, Miura T and
Shirahata S: Transforming growth factor β triggers two
independent-senescence programs in cancer cells. Biochem Biophys
Res Commun. 255:110–115. 1999. View Article : Google Scholar : PubMed/NCBI
|
12
|
Qu Y, Zhang L, Kang Z, Jiang W and Lv C:
Ponatinib ameliorates pulmonary fibrosis by suppressing
TGF-β1/Smad3 pathway. Pulm Pharmacol Ther. 34:1–7. 2015. View Article : Google Scholar : PubMed/NCBI
|
13
|
Raghu G, Rochwerg B, Zhang Y, Garcia CA,
Azuma A, Behr J, Brozek JL, Collard HR, Cunningham W, Homma S, et
al: An official ATS/ERS/JRS/ALAT clinical practice guideline:
Treatment of idiopathic pulmonary fibrosis. Am J Respir Crit Care
Med. 192:e3–e19. 2015. View Article : Google Scholar : PubMed/NCBI
|
14
|
Martin M: Cutadapt removes adapter
sequences from high-throughput sequencing reads. EMBnet J.
17:10–12. 2011. View Article : Google Scholar
|
15
|
Kim D, Pertea G, Trapnell C, Pimentel H,
Kelley R and Salzberg SL: TopHat2: Accurate alignment of
transcriptomes in the presence of insertions, deletions and gene
fusions. Genome Bio. 14:R362013. View Article : Google Scholar
|
16
|
Ashburner M, Ball CA, Blake JA, Botstein
D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT,
et al: Gene Ontology: Tool for the unification of biology. Nature
genetics. 25:25–29. 2000. View
Article : Google Scholar : PubMed/NCBI
|
17
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
18
|
Mercer TR, Dinger ME and Mattick JS: Long
non-coding RNAs: Insights into functions. Nat Rev Genet.
10:155–159. 2009. View
Article : Google Scholar : PubMed/NCBI
|
19
|
Ponting CP, Oliver PL and Reik W:
Evolution and functions of long noncoding RNAs. Cell. 136:629–641.
2009. View Article : Google Scholar : PubMed/NCBI
|
20
|
De Oliveira NC, Julliard W, Osaki S,
Maloney JD, Cornwell RD, Sonetti DA and Meyer KC: Lung
transplantation for high-risk patients with idiopathic pulmonary
fibrosis. Sarcoidosis Vasc Diffuse Lung Dis. 33:235–241.
2016.PubMed/NCBI
|
21
|
Cesana M, Cacchiarelli D, Legnini I,
Santini T, Sthandier O, Chinappi M, Tramontano A and Bozzoni I: A
long noncoding RNA controls muscle differentiation by functioning
as a competing endogenous RNA. Cell. 147:358–369. 2011. View Article : Google Scholar : PubMed/NCBI
|
22
|
Cheng EC and Lin H: Repressing the
repressor: A lincRNA as a MicroRNA sponge in embryonic stem cell
self-renewal. Dev Cell. 25:1–2. 2013. View Article : Google Scholar : PubMed/NCBI
|
23
|
Song X, Cao G, Jing L, Lin S, Wang X,
Zhang J, Wang M, Liu W and Lv C: Analysing the relationship between
lncRNA and protein-coding gene and the role of lncRNA as ceRNA in
pulmonary fibrosis. J Cell Mol Med. 18:991–1003. 2014. View Article : Google Scholar : PubMed/NCBI
|
24
|
Wilusz JE, Sunwoo H and Spector DL: Long
noncoding RNAs: Functional surprises from the RNA world. Genes Dev.
23:1494–1504. 2009. View Article : Google Scholar : PubMed/NCBI
|
25
|
Lee DY, Moon J, Lee S-T, Jung KH, Park DK,
Yoo JS, Sunwoo JS, Byun JI, Shin JW, Jeon D, et al: Distinct
expression of long non-coding RNAs in an Alzheimer's disease model.
J Alzheimers Dis. 45:837–849. 2015.PubMed/NCBI
|
26
|
Faghihi MA, Modarresi F, Khalil AM, Wood
DE, Sahagan BG, Morgan TE, Finch CE, St Laurent G III, Kenny PJ and
Wahlestedt C: Expression of a noncoding RNA is elevated in
Alzheimer's disease and drives rapid feed-forward regulation of
β-secretase. Nat Med. 14:723–730. 2008. View Article : Google Scholar : PubMed/NCBI
|
27
|
Faghihi MA, Zhang M, Huang J, Modarresi F,
Van der Brug MP, Nalls MA, Cookson MR, St-Laurent G III and
Wahlestedt C: Evidence for natural antisense transcript-mediated
inhibition of microRNA function. Genome Biol. 11:R562010.
View Article : Google Scholar : PubMed/NCBI
|
28
|
Carrieri C, Cimatti L, Biagioli M, Beugnet
A, Zucchelli S, Fedele S, Pesce E, Ferrer I, Collavin L, Santoro C,
et al: Long non-coding antisense RNA controls Uchl1 translation
through an embedded SINEB2 repeat. Nature. 491:454–457. 2012.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Li X, Wu Z, Fu X and Han W: lncRNAs:
Insights into their function and mechanics in underlying disorders.
Mutat Res Rev Mutat Res. 762:1–21. 2014. View Article : Google Scholar : PubMed/NCBI
|
30
|
Yang D, Lian T, Tu J, Gaur U, Mao X, Fan
X, Li D, Li Y and Yang M: LncRNA mediated regulation of aging
pathways in Drosophila melanogaster during dietary restriction.
Aging (Albany NY). 8:2182–2203. 2016. View Article : Google Scholar : PubMed/NCBI
|
31
|
Huang C, Yang Y and Liu L: Interaction of
long noncoding RNAs and microRNAs in the pathogenesis of idiopathic
pulmonary fibrosis. Physiol Genomics. 47:463–469. 2015. View Article : Google Scholar : PubMed/NCBI
|
32
|
Mendelsohn AR and Larrick JW: Rapamycin as
an antiaging therapeutic? Targeting mammalian target of rapamycin
to treat Hutchinson-Gilford Progeria and neurodegenerative
diseases. Rejuvenation Res. 14:437–441. 2011. View Article : Google Scholar : PubMed/NCBI
|
33
|
Yoshizaki A, Yanaba K, Yoshizaki A, Iwata
Y, Komura K, Ogawa F, Takenaka M, Shimizu K, Asano Y, Hasegawa M,
et al: Treatment with rapamycin prevents fibrosis in tight-skin and
bleomycin-induced mouse models of systemic sclerosis. Arthritis
Rheum. 62:2476–2487. 2010. View Article : Google Scholar : PubMed/NCBI
|
34
|
Chang W, Wei K, Ho L, Berry GJ, Jacobs SS,
Chang CH and Rosen GD: A critical role for the mTORC2 pathway in
lung fibrosis. PLoS One. 9:e1061552014. View Article : Google Scholar : PubMed/NCBI
|
35
|
Nho RS and Hergert P: IPF fibroblasts are
desensitized to type I collagen matrix-induced cell death by
suppressing low autophagy via aberrant Akt/mTOR kinases. PLoS One.
9:e946162014. View Article : Google Scholar : PubMed/NCBI
|
36
|
Park JS, Park HJ, Park YS, Lee SM, Yim JJ,
Yoo CG, Han SK and Kim YW: Clinical significance of mTOR, ZEB1,
ROCK1 expression in lung tissues of pulmonary fibrosis patients.
BMC Pulm Med. 14:1682014. View Article : Google Scholar : PubMed/NCBI
|
37
|
Madala SK, Thomas G, Edukulla R, Davidson
C, Schmidt S, Schehr A and Hardie WD: p70 ribosomal S6 kinase
regulates subpleural fibrosis following transforming growth
factor-α expression in the lung. Am J Physiol Lung Cell Mol
Physiol. 310:L175–L186. 2016. View Article : Google Scholar : PubMed/NCBI
|
38
|
Li FZ, Cai PC, Song LJ, Zhou LL, Zhang Q,
Rao SS, Xia Y, Xiang F, Xin JB, Greer PA, et al: Crosstalk between
calpain activation and TGF-β1 augments collagen-I synthesis in
pulmonary fibrosis. Biochim Biophys Acta. 1852:1796–1804. 2015.
View Article : Google Scholar : PubMed/NCBI
|
39
|
Strieter RM and Mehrad B: New mechanisms
of pulmonary fibrosis. Chest. 136:1364–1370. 2009. View Article : Google Scholar : PubMed/NCBI
|