|
1
|
Ljungberg B, Campbell SC, Choi HY, Jacqmin
D, Lee JE, Weikert S and Kiemeney LA: The epidemiology of renal
cell carcinoma. Eur Urol. 60:615–621. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kabaria R, Klaassen Z and Terris MK: Renal
cell carcinoma: Links and risks. Int J Nephrol Renovasc Dis.
9:45–52. 2016.PubMed/NCBI
|
|
4
|
Moch H, Artibani W, Delahunt B, Ficarra V,
Knuechel R, Montorsi F, Patard JJ, Stief CG, Sulser T and Wild PJ:
Reassessing the current UICC/AJCC TNM staging for renal cell
carcinoma. Eur Urol. 56:636–643. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Bilim V, Ougolkov A, Yuuki K, Naito S,
Kawazoe H, Muto A, Oya M, Billadeau D, Motoyama T and Tomita Y:
Glycogen synthase kinase-3: A new therapeutic target in renal cell
carcinoma. Br J Cancer. 101:2005–2014. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Warburg O: On the origin of cancer cells.
Science. 123:309–314. 1956. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yuen CA, Asuthkar S, Guda MR, Tsung AJ and
Velpula KK: Cancer stem cell molecular reprogramming of the Warburg
effect in glioblastomas: A new target gleaned from an old concept.
CNS Oncol. 5:101–108. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Taniguchi K, Sakai M, Sugito N, Kumazaki
M, Shinohara H, Yamada N, Nakayama T, Ueda H, Nakagawa Y, Ito Y, et
al: PTBP1-associated microRNA-1 and −133b suppress the Warburg
effect in colorectal tumors. Oncotarget. 7:18940–18952. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Soltysova A, Breza J, Takacova M,
Feruszova J, Hudecova S, Novotna B, Rozborilova E, Pastorekova S,
Kadasi L and Krizanova O: Deregulation of energetic metabolism in
the clear cell renal cell carcinoma: A multiple pathway analysis
based on microarray profiling. Int J Oncol. 47:287–295. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lim HY, Yip YM, Chiong E, Tiong HY,
Halliwell B, Esuvaranathan K and Wong KP: Metabolic signatures of
renal cell carcinoma. Biochem Biophys Res Commun. 460:938–943.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Goldman RD, Kaplan NO and Hall TC: Lactic
dehydrogenase in human neoplastic tissues. Cancer Res. 24:389–399.
1964.PubMed/NCBI
|
|
12
|
Sun X, Sun Z, Zhu Z, Guan H, Zhang J,
Zhang Y, Xu H and Sun M: Clinicopathological significance and
prognostic value of lactate dehydrogenase A expression in gastric
cancer patients. PloS One. 9:e910682014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Xian ZY, Liu JM, Chen QK, Chen HZ, Ye CJ,
Xue J, Yang HQ, Li JL, Liu XF and Kuang SJ: Inhibition of LDHA
suppresses tumor progression in prostate cancer. Tumour Biol.
36:8093–8100. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Qiu H, Jackson AL, Kilgore JE, Zhong Y,
Chan LL, Gehrig PA, Zhou C and Bae-Jump VL: JQ1 suppresses tumor
growth through downregulating LDHA in ovarian cancer. Oncotarget.
6:6915–6930. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yao F, Zhao T, Zhong C, Zhu J and Zhao H:
LDHA is necessary for the tumorigenicity of esophageal squamous
cell carcinoma. Tumour Biol. 34:25–31. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Fantin VR, St-Pierre J and Leder P:
Attenuation of LDH-A expression uncovers a link between glycolysis,
mitochondrial physiology, and tumor maintenance. Cancer Cell.
9:425–434. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Girgis H, Masui O, White NM, Scorilas A,
Rotondo F, Seivwright A, Gabril M, Filter ER, Girgis AH, Bjarnason
GA, et al: Lactate Dehydrogenase A is a potential prognostic marker
in clear cell renal cell carcinoma. Mol Cancer. 13:1012014.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wang X, Xu L, Wu Q, Liu M, Tang F, Cai Y,
Fan W, Huang H and Gu X: Inhibition of LDHA deliver potential
anticancer performance in renal cell carcinoma. Urol Int. 2016.
|
|
19
|
Thiery JP and Sleeman JP: Complex networks
orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell
Biol. 7:131–142. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
20
|
Cao J, Wang H, Chen F, Fang J, Xu A, Xi W,
Zhang S, Wu G and Wang Z: Galangin inhibits cell invasion by
suppressing the epithelial-mesenchymal transition and inducing
apoptosis in renal cell carcinoma. Mol Med Rep. 13:4238–4244. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Giannelli G, Koudelkova P, Dituri F and
Mikulits W: Role of epithelial to mesenchymal transition in
hepatocellular carcinoma. J Hepatol. 65:798–808. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Nakazawa M and Kyprianou N:
Epithelial-mesenchymal-transition regulators in prostate cancer:
Androgens and beyond. J Steroid Biochem Mol Biol. 166:84–90. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Smith BN and Bhowmick NA: Role of EMT in
metastasis and therapy resistance. J Clin Med. 5:E172016.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Piva F, Giulietti M, Santoni M, Occhipinti
G, Scarpelli M, Lopez-Beltran A, Cheng L, Principato G and
Montironi R: Epithelial to mesenchymal transition in renal cell
carcinoma: Implications for cancer therapy. Mol Diagn Ther.
20:111–117. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Jiang F, Ma S, Xue Y, Hou J and Zhang Y:
LDH-A promotes malignant progression via activation of
epithelial-to-mesenchymal transition and conferring stemness in
muscle-invasive bladder cancer. Biochem Biophys Res Commun.
469:985–992. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Chen Y, Sun Y, Rao Q, Xu H, Li L and Chang
C: Androgen receptor (AR) suppresses miRNA-145 to promote renal
cell carcinoma (RCC) progression independent of VHL status.
Oncotarget. 6:31203–31215. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Hatzivassiliou G, Zhao F, Bauer DE,
Andreadis C, Shaw AN, Dhanak D, Hingorani SR, Tuveson DA and
Thompson CB: ATP citrate lyase inhibition can suppress tumor cell
growth. Cancer Cell. 8:311–321. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kaplan NO: Lactate dehydrogenase-structure
and function. Brookhaven Symp Biol. 17:131–153. 1964.PubMed/NCBI
|
|
29
|
Weide B, Elsasser M, Buttner P,
Pflugfelder A, Leiter U, Eigentler TK, Bauer J, Witte M, Meier F
and Garbe C: Serum markers lactate dehydrogenase and S100B predict
independently disease outcome in melanoma patients with distant
metastasis. Br J Cancer. 107:422–428. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Brown JE, Cook RJ, Lipton A and Coleman
RE: Serum lactate dehydrogenase is prognostic for survival in
patients with bone metastases from breast cancer: A retrospective
analysis in bisphosphonate-treated patients. Clin Cancer Res.
18:6348–6355. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Girgis H, Masui O, White NM, Scorilas A,
Rotondo F, Seivwright A, Gabril M, Filter ER, Girgis AH, Bjarnason
GA, et al: Lactate dehydrogenase A is a potential prognostic marker
in clear cell renal cell carcinoma. Mol Cancer. 13:1012014.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Han T, Kang D, Ji D, Wang X, Zhan W, Fu M,
Xin HB and Wang JB: How does cancer cell metabolism affect tumor
migration and invasion? Cell Adh Migr. 7:395–403. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Sanders E and Diehl S: Analysis and
interpretation of transcriptomic data obtained from extended
Warburg effect genes in patients with clear cell renal cell
carcinoma. Oncoscience. 2:151–186. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Garber K: Energy deregulation: Licensing
tumors to grow. Science. 312:1158–1159. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Sanders E and Diehl S: Analysis and
interpretation of transcriptomic data obtained from extended
Warburg effect genes in patients with clear cell renal cell
carcinoma. Oncoscience. 2:151–186. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Wang X, Xu L, Wu Q, Liu M, Tang F, Cai Y,
Fan W, Huang H and Gu X: Inhibition of LDHA deliver potential
anticancer performance in renal cell carcinoma. Urol Int. 2016.
|
