|
1
|
Khalili J: Oral cancer: Risk factors,
prevention and diagnostic. Exp Oncol. 30:259–264. 2008.PubMed/NCBI
|
|
2
|
Lee CH, Shih YL, Lee MH, Au MK, Chen YL,
Lu HF and Chung JG: Bufalin induces apoptosis of human osteosarcoma
U-2 os cells through endoplasmic reticulum stress, caspase- and
mitochondria-dependent signaling pathways. Molecules. 22:E4372017.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Gomez DR, Zhung JE, Gomez J, Chan K, Wu
AJ, Wolden SL, Pfister DG, Shaha A, Shah JP, Kraus DH, et al:
Intensity-modulated radiotherapy in postoperative treatment of oral
cavity cancers. Int J Radiat Oncol Biol Phys. 73:1096–1103. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Major AG, Pitty LP and Farah CS: Cancer
stem cell markers in head and neck squamous cell carcinoma. Stem
Cells Int. 2013:3194892013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Urban D, Corry J and Rischin D: What is
the best treatment for patients with human papillomavirus-positive
and -negative oropharyngeal cancer? Cancer. 120:1462–1470. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Krenn L and Kopp B: Bufadienolides from
animal and plant sources. Phytochemistry. 48:1–29. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Meng Z, Yang P, Shen Y, Bei W, Zhang Y, Ge
Y, Newman RA, Cohen L, Liu L, Thornton B, et al: Pilot study of
huachansu in patients with hepatocellular carcinoma, nonsmall-cell
lung cancer, or pancreatic cancer. Cancer. 115:5309–5318. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Han KQ, Huang G, Gu W, Su YH, Huang XQ and
Ling CQ: Anti-tumor activities and apoptosis-regulated mechanisms
of bufalin on the orthotopic transplantation tumor model of human
hepatocellular carcinoma in nude mice. World J Gastroenterol.
13:3374–3379. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Hashimoto S, Jing Y, Kawazoe N, Masuda Y,
Nakajo S, Yoshida T, Kuroiwa Y and Nakaya K: Bufalin reduces the
level of topoisomerase II in human leukemia cells and affects the
cytotoxicity of anticancer drugs. Leuk Res. 21:875–883. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Watabe M, Ito K, Masuda Y, Nakajo S and
Nakaya K: Activation of AP-1 is required for bufalin-induced
apoptosis in human leukemia U937 cells. Oncogene. 16:779–787. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li D, Qu X, Hou K, Zhang Y, Dong Q, Teng
Y, Zhang J and Liu Y: PI3 K/Akt is involved in bufalin-induced
apoptosis in gastric cancer cells. Anticancer Drugs. 20:59–64.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yu CH, Kan SF, Pu HF, Jea Chien E and Wang
PS: Apoptotic signaling in bufalin- and cinobufagin-treated
androgen-dependent and -independent human prostate cancer cells.
Cancer Sci. 99:2467–2476. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Shen S, Zhang Y, Wang Z, Liu R and Gong X:
Bufalin induces the interplay between apoptosis and autophagy in
glioma cells through endoplasmic reticulum stress. Int J Biol Sci.
10:212–224. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Huang WW, Yang JS, Pai SJ, Wu PP, Chang
SJ, Chueh FS, Fan MJ, Chiou SM, Kuo HM, Yeh CC, et al: Bufalin
induces G0/G1 phase arrest through inhibiting the levels of cyclin
D cyclin E, CDK2 and CDK4 and triggers apoptosis via mitochondrial
signaling pathway in T24 human bladder cancer cells. Mutat Res.
732:26–33. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Jiang Y, Zhang Y, Luan J, Duan H, Zhang F,
Yagasaki K and Zhang G: Effects of bufalin on the proliferation of
human lung cancer cells and its molecular mechanisms of action.
Cytotechnology. 62:573–583. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Zhu Z, Li E, Liu Y, Gao Y, Sun H, Ma G,
Wang Z, Liu X, Wang Q, Qu X, et al: Inhibition of Jak-STAT3 pathway
enhances bufalin-induced apoptosis in colon cancer SW620 cells.
World J Surg Oncol. 10:2282012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wu SH, Wu TY, Hsiao YT, Lin JH, Hsu SC,
Hsia TC, Yang ST, Hsu WH and Chung JG: Bufalin induces cell death
in human lung cancer cells through disruption of DNA damage
response pathways. Am J Chin Med. 42:729–742. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Chang Y-M, Velmurugan BK, Kuo W-W, Chen
Y-S, Ho T-J, Tsai C-T, Ye C-X, Tsai C-H, Tsai F-J and Huang C-Y:
Inhibitory effect of alpinate Oxyphyllae fructus extracts on Ang
II-induced cardiac pathological remodeling-related pathways in H9c2
cardiomyoblast cells. Biomedicine. 3:148–152. 2013. View Article : Google Scholar
|
|
19
|
Yu FS, Huang AC, Yang JS, Yu CS, Lu CC,
Chiang JH, Chiu CF and Chung JG: Safrole induces cell death in
human tongue squamous cancer SCC-4 cells through
mitochondria-dependent caspase activation cascade apoptotic
signaling pathways. Environ Toxicol. 27:433–444. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chueh FS, Chen YL, Hsu SC, Yang JS, Hsueh
SC, Ji BC, Lu HF and Chung JG: Triptolide induced DNA damage in
A375.S2 human malignant melanoma cells is mediated via reduction of
DNA repair genes. Oncol Rep. 29:613–618. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Liu KC, Yen CY, Wu RS, Yang JS, Lu HF, Lu
KW, Lo C, Chen HY, Tang NY, Wu CC and Chung JG: The roles of
endoplasmic reticulum stress and mitochondrial apoptotic signaling
pathway in quercetin-mediated cell death of human prostate cancer
PC-3 cells. Environ Toxicol. 29:428–439. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lin M-C, Tsai S-Y, Wang F-Y, Liu F-H, Syu
J-N and Tang F-Y: Leptin induces cell invasion and the upregulation
of matrilysin in human colon cancer cells. Biomedicine. 3:174–180.
2013. View Article : Google Scholar
|
|
23
|
Iglesias-Guimarais V, Gil-Guinon E,
Sanchez-Osuna M, Casanelles E, Garcia-Belinchon M, Comella JX and
Yuste VJ: Chromatin collapse during caspase-dependent apoptotic
cell death requires DNA fragmentation factor, 40-kDa
subunit-/caspase-activated deoxyribonuclease-mediated 3′-OH
single-strand DNA breaks. J Biol Chem. 288:9200–9215. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Jiang L, Zhao MN, Liu TY, Wu XS, Weng H,
Ding Q, Shu YJ, Bao RF, Li ML, Mu JS, et al: Bufalin induces cell
cycle arrest and apoptosis in gallbladder carcinoma cells. Tumour
Biol. 35:10931–10941. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zhang DM, Liu JS, Tang MK, Yiu A, Cao HH,
Jiang L, Chan JY, Tian HY, Fung KP and Ye WC: Bufotalin from
venenum bufonis inhibits growth of multidrug resistant HepG2 cells
through G2/M cell cycle arrest and apoptosis. Eur J Pharmacol.
692:19–28. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wu SH, Bau DT, Hsiao YT, Lu KW, Hsia TC,
Lien JC, Ko YC, Hsu WH, Yang ST, Huang YP and Chung JG: Bufalin
induces apoptosis in vitro and has Antitumor activity against human
lung cancer xenografts in vivo. Environ Toxicol. 32:1305–1317.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yin PH, Liu X, Qiu YY, Cai JF, Qin JM, Zhu
HR and Li Q: Anti-tumor activity and apoptosis-regulation
mechanisms of bufalin in various cancers: new hope for cancer
patients. Asian Pac J Cancer Prev. 13:5339–5343. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhao H, Zhao D, Tan G, Liu Y, Zhuang L and
Liu T: Bufalin promotes apoptosis of gastric cancer by
down-regulation of miR-298 targeting bax. Int J Clin Exp Med.
8:3420–3428. 2015.PubMed/NCBI
|
|
29
|
Hong SH and Choi YH: Bufalin induces
apoptosis through activation of both the intrinsic and extrinsic
pathways in human bladder cancer cells. Oncol Rep. 27:114–120.
2012.PubMed/NCBI
|
|
30
|
Jing Y, Watabe M, Hashimoto S, Nakajo S
and Nakaya K: Cell cycle arrest and protein kinase modulating
effect of bufalin on human leukemia ML1 cells. Anticancer Res.
14:1193–1198. 1994.PubMed/NCBI
|
|
31
|
Numazawa S, Shinoki MA, Ito H, Yoshida T
and Kuroiwa Y: Involvement of Na+, K(+)-ATPase
inhibition in K562 cell differentiation induced by bufalin. J Cell
Physiol. 160:113–120. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Liu K, Cang S, Ma Y and Chiao JW:
Synergistic effect of paclitaxel and epigenetic agent phenethyl
isothiocyanate on growth inhibition, cell cycle arrest and
apoptosis in breast cancer cells. Cancer Cell Int. 13:102013.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chu YL, Ho CT, Chung JG, Raghu R, Lo YC
and Sheen LY: Allicin induces anti-human liver cancer cells through
the p53 gene modulating apoptosis and autophagy. J Agric Food Chem.
61:9839–9848. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Green DR and Fitzgerald P: Just so stories
about the evolution of apoptosis. Curr Biol. 26:R620–R627. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Li W, Zhao L, Wei T, Zhao Y and Chen C:
The inhibition of death receptor mediated apoptosis through
lysosome stabilization following internalization of
carboxyfullerene nanoparticles. Biomaterials. 32:4030–4041. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Grunnet LG, Aikin R, Tonnesen MF,
Paraskevas S, Blaabjerg L, Storling J, Rosenberg L, Billestrup N,
Maysinger D and Mandrup-Poulsen T: Proinflammatory cytokines
activate the intrinsic apoptotic pathway in beta-cells. Diabetes.
58:1807–1815. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Santin I, Moore F, Colli ML, Gurzov EN,
Marselli L, Marchetti P and Eizirik DL: PTPN2, a candidate gene for
type 1 diabetes, modulates pancreatic beta-cell apoptosis via
regulation of the BH3-only protein Bim. Diabetes. 60:3279–3288.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Milutinovic S, Kashyap AK, Yanagi T, Wimer
C, Zhou S, O'Neil R, Kurtzman AL, Faynboym A, Xu L, Hannum CH, et
al: Dual agonist surrobody simultaneously activates death receptors
dr4 and dr5 to induce cancer cell death. Mol Cancer Ther.
15:114–124. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Lin FL, Hsu JL, Chou CH, Wu WJ, Chang CI
and Liu HJ: Activation of p38 MAPK by damnacanthal mediates
apoptosis in SKHep 1 cells through the DR5/TRAIL and
TNFR1/TNF-alpha and p53 pathways. Eur J Pharmacol. 650:120–129.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Chen Y, Azad MB and Gibson SB: Superoxide
is the major reactive oxygen species regulating autophagy. Cell
Death Differ. 16:1040–1052. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Ip SW, Chu YL, Yu CS, Chen PY, Ho HC, Yang
JS, Huang HY, Chueh FS, Lai TY and Chung JG: Bee venom induces
apoptosis through intracellular Ca2+ -modulated
intrinsic death pathway in human bladder cancer cells. Int J Urol.
19:61–70. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Chiu TH, Lan KY, Yang MD, Lin JJ, Hsia TC,
Wu CT, Yang JS, Chueh FS and Chung JG: Diallyl sulfide promotes
cell-cycle arrest through the p53 expression and triggers induction
of apoptosis via caspase- and mitochondria-dependent signaling
pathways in human cervical cancer Ca Ski cells. Nutr Cancer.
65:505–514. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Tsai CW, Yang MD, Hsia TC, Chang WS, Hsu
CM, Hsieh YH, Chung JG and Bau DT: Dithiothreitol enhanced
arsenic-trioxide-induced cell apoptosis in cultured oral cancer
cells via mitochondrial dysfunction and endoplasmic reticulum
stress. Environ Toxicol. 32:17–27. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Mohan S, Abdelwahab SI, Kamalidehghan B,
Syam S, May KS, Harmal NS, Shafifiyaz N, Hadi AH, Hashim NM,
Rahmani M, et al: Involvement of NF-kappaB and Bcl2/Bax signaling
pathways in the apoptosis of MCF7 cells induced by a xanthone
compound Pyranocycloartobiloxanthone A. Phytomedicine.
19:1007–1015. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Ma YS, Hsu SC, Weng SW, Yu CC, Yang JS,
Lai KC, Lin JP, Lin JG and Chung JG: Crude extract of Rheum
palmatum L induced cell death in LS1034 human colon cancer cells
acts through the caspase-dependent and -independent pathways.
Environ Toxicol. 29:969–980. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Wu J, Tan Z, Chen J and Dong C:
Cyclovirobuxine D inhibits cell proliferation and induces
mitochondria-mediated apoptosis in human gastric cancer cells.
Molecules. 20:20659–20668. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Chiang JH, Yang JS, Ma CY, Yang MD, Huang
HY, Hsia TC, Kuo HM, Wu PP, Lee TH and Chung JG: Danthron, an
anthraquinone derivative, induces DNA damage and caspase
cascades-mediated apoptosis in SNU-1 human gastric cancer cells
through mitochondrial permeability transition pores and
Bax-triggered pathways. Chem Res Toxicol. 24:20–29. 2011.
View Article : Google Scholar : PubMed/NCBI
|
