|
1
|
Tate ML Knothe, Knothe U and Niederer P:
Experimental elucidation of mechanical load-induced fluid flow and
its potential role in bone metabolism and functional adaptation. Am
J Med Sci. 316:189–195. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kufahl RH and Saha S: A theoretical model
for stress-generated fluid flow in the canaliculi-lacunae network
in bone tissue. J Biomech. 23:171–180. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kapur S, Baylink DJ and Lau KH: Fluid flow
shear stress stimulates human osteoblast proliferation and
differentiation through multiple interacting and competing signal
transduction pathways. Bone. 32:241–251. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Liu X, Zhang X and Lee I: A quantitative
study on morphological responses of osteoblastic cells to fluid
shear stress. Acta Biochim Biophys Sin (Shanghai). 42:195–201.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yu W, Qu H, Hu G, Zhang Q, Song K, Guan H,
Liu T and Qin J: A microfluidic-based multi-shear device for
investigating the effects of low fluid-induced stresses on
osteoblasts. PLoS One. 9:e899662014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Prescott DM: Regulation of cell
reproduction. Cancer Res. 28:1815–1820. 1968.PubMed/NCBI
|
|
7
|
Dyson N: The regulation of E2F by
pRB-family proteins. Genes Dev. 12:2245–2262. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Spencer SL, Cappell SD, Tsai FC, Overton
KW, Wang CL and Meyer T: The proliferation-quiescence decision is
controlled by a bifurcation in CDK2 activity at mitotic exit. Cell.
155:369–383. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Luan Y, Yu XP, Xu K, Ding B, Yu J, Huang
Y, Yang N, Lengyel P, Di Cesare PE and Liu CJ: The retinoblastoma
protein is an essential mediator of osteogenesis that links the
p204 protein to the Cbfa1 transcription factor thereby increasing
its activity. J Biol Chem. 282:16860–16870. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Thomas DM, Carty SA, Piscopo DM, Lee JS,
Wang WF, Forrester WC and Hinds PW: The retinoblastoma protein acts
as a transcriptional coactivator required for osteogenic
differentiation. Mol Cell. 8:303–316. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Akhter MP, Wells DJ, Short SJ, Cullen DM,
Johnson ML, Haynatzki GR, Babij P, Allen KM, Yaworsky PJ, Bex F and
Recker RR: Bone biomechanical properties in LRP5 mutant mice. Bone.
35:162–169. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Chen NX, Geist DJ, Genetos DC, Pavalko FM
and Duncan RL: Fluid shear-induced NFkappaB translocation in
osteoblasts is mediated by intracellular calcium release. Bone.
33:399–410. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Chen NX, Ryder KD, Pavalko FM, Turner CH,
Burr DB, Qiu J and Duncan RL: Ca(2+) regulates fluid shear-induced
cytoskeletal reorganization and gene expression in osteoblasts. Am
J Physiol Cell Physiol. 278:C989–C997. 2000.PubMed/NCBI
|
|
14
|
Jing D, Baik AD, Lu XL, Zhou B, Lai X,
Wang L, Luo E and Guo XE: In situ intracellular calcium
oscillations in osteocytes in intact mouse long bones under dynamic
mechanical loading. FASEB J. 28:1582–1592. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Lu XL, Huo B, Park M and Guo XE: Calcium
response in osteocytic networks under steady and oscillatory fluid
flow. Bone. 51:466–473. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Pilbeam CC, Raisz LG, Voznesensky O,
Alander CB, Delman BN and Kawaguchi H: Autoregulation of inducible
prostaglandin G/H synthase in osteoblastic cells by prostaglandins.
J Bone Miner Res. 10:406–414. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wadhwa S, Choudhary S, Voznesensky M,
Epstein M, Raisz L and Pilbeam C: Fluid flow induces COX-2
expression in MC3T3-E1 osteoblasts via a PKA signaling pathway.
Biochem Biophys Res Commun. 297:46–51. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wang B, Du T, Wang Y, Yang C, Zhang S and
Cao X: Focal adhesion kinase signaling pathway is involved in
mechanotransduction in MG-63 cells. Biochem Biophys Res Commun.
410:671–676. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ducy P, Zhang R, Geoffroy V, Ridall AL and
Karsenty G: Osf2/Cbfa1: A transcriptional activator of osteoblast
differentiation. Cell. 89:747–754. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zayzafoon M, Fulzele K and McDonald JM:
Calmodulin and calmodulin-dependent kinase IIalpha regulate
osteoblast differentiation by controlling c-fos expression. J Biol
Chem. 280:7049–7059. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Gebken J, Lüders B, Notbohm H, Klein HH,
Brinckmann J, Müller PK and Bätge B: Hypergravity stimulates
collagen synthesis in human osteoblast-like cells: Evidence for the
involvement of p44/42 MAP-kinases (ERK 1/2). J Biochem.
126:676–682. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Jessop HL, Rawlinson SC, Pitsillides AA
and Lanyon LE: Mechanical strain and fluid movement both activate
extracellular regulated kinase (ERK) in osteoblast-like cells but
via different signaling pathways. Bone. 31:186–194. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Matsuda N, Morita N, Matsuda K and
Watanabe M: Proliferation and differentiation of human osteoblastic
cells associated with differential activation of MAP kinases in
response to epidermal growth factor, hypoxia, and mechanical stress
in vitro. Biochem Biophys Res Commun. 249:350–354. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wadhwa S, Godwin SL, Peterson DR, Epstein
MA, Raisz LG and Pilbeam CC: Fluid flow induction of
cyclo-oxygenase 2 gene expression in osteoblasts is dependent on an
extracellular signal-regulated kinase signaling pathway. J Bone
Miner Res. 17:266–274. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
You J, Reilly GC, Zhen X, Yellowley CE,
Chen Q, Donahue HJ and Jacobs CR: Osteopontin gene regulation by
oscillatory fluid flow via intracellular calcium mobilization and
activation of mitogen-activated protein kinase in MC3T3-E1
osteoblasts. J Biol Chem. 276:13365–13371. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Galindo M, Pratap J, Young DW,
Hovhannisyan H, Im HJ, Choi JY, Lian JB, Stein JL, Stein GS and van
Wijnen AJ: The bone-specific expression of Runx2 oscillates during
the cell cycle to support a G1-related antiproliferative function
in osteoblasts. J Biol Chem. 280:20274–20285. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Franceschi RT, Xiao G, Jiang D,
Gopalakrishnan R, Yang S and Reith E: Multiple signaling pathways
converge on the Cbfa1/Runx2 transcription factor to regulate
osteoblast differentiation. Connective Tissue Res. 44 Suppl
1:S109–S116. 2003. View Article : Google Scholar
|
|
29
|
Enarsson M, Erlandsson A, Larsson H and
Forsberg-Nilsson K: Extracellular signal-regulated protein kinase
signaling is uncoupled from initial differentiation of central
nervous system stem cells to neurons. Mol Cancer Res. 1:147–154.
2002.PubMed/NCBI
|
|
30
|
Howe AK and Juliano RL: Distinct
mechanisms mediate the initial and sustained phases of
integrin-mediated activation of the Raf/MEK/mitogen-activated
protein kinase cascade. J Biol Chem. 273:27268–27274. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Park KS, Lee NG, Lee KH, Seo JT and Choi
KY: The ERK pathway involves positive and negative regulations of
HT-29 colorectal cancer cell growth by extracellular zinc. Am J
Physiol Gastrointest Liver Physiol. 285:G1181–G1188. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Woods D, Parry D, Cherwinski H, Bosch E,
Lees E and McMahon M: Raf-induced proliferation or cell cycle
arrest is determined by the level of Raf activity with arrest
mediated by p21Cip1. Mol Cell Biol. 17:5598–5611. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Vezeridis PS, Semeins CM, Chen Q and
Klein-Nulend J: Osteocytes subjected to pulsating fluid flow
regulate osteoblast proliferation and differentiation. Biochem
Biophys Res Commun. 348:1082–1088. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Li YJ, Batra NN, You L, Meier SC, Coe IA,
Yellowley CE and Jacobs CR: Oscillatory fluid flow affects human
marrow stromal cell proliferation and differentiation. J Orthop
Res. 22:1283–1289. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Chau JF, Leong WF and Li B: Signaling
pathways governing osteoblast proliferation, differentiation and
function. Histol Histopathol. 24:1593–1606. 2009.PubMed/NCBI
|
|
36
|
Komori T: Cbfa1/Runx2, an essential
transcription factor for the regulation of osteoblast
differentiation. Nihon Rinsho. 60(Suppl 3): S91–S97. 2002.(In
Japanese).
|
|
37
|
Komori T: Regulation of osteoblast
differentiation by Runx2. Adv Exp Med Biol. 658:43–49. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhao LG, Chen SL, Teng YJ, An LP, Wang J,
Ma JL and Xia YY: The MEK5/ERK5 pathway mediates fluid shear stress
promoted osteoblast differentiation. Connect Tissue Res. 55:96–102.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Kern B, Shen J, Starbuck M and Karsenty G:
Cbfa1 contributes to the osteoblast-specific expression of type I
collagen genes. J Biol Chem. 276:7101–7107. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Selvamurugan N, Chou WY, Pearman AT,
Pulumati MR and Partridge NC: Parathyroid hormone regulates the rat
collagenase-3 promoter in osteoblastic cells through the
cooperative interaction of the activator protein-1 site and the
runt domain binding sequence. J Biol Chem. 273:10647–10657. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Braun AP and Schulman H: The
multifunctional calcium/calmodulin-dependent protein kinase: From
form to function. Annu Rev Physiol. 57:417–445. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Colomer JM and Means AR: Chronic elevation
of calmodulin in the ventricles of transgenic mice increases the
autonomous activity of calmodulin-dependent protein kinase II,
which regulates atrial natriuretic factor gene expression. Mol
Endocrinol. 14:1125–1136. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Akimoto S, Mitsumata M, Sasaguri T and
Yoshida Y: Laminar shear stress inhibits vascular endothelial cell
proliferation by inducing cyclin-dependent kinase inhibitor
p21(Sdi1/Cip1/Waf1). Circ Res. 86:185–190. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Jung GA, Yoon JY, Moon BS, Yang DH, Kim
HY, Lee SH, Bryja V, Arenas E and Choi KY: Valproic acid induces
differentiation and inhibition of proliferation in neural
progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway.
BMC Cell Biol. 9:662008. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Yuan K, Chung LW, Siegal GP and Zayzafoon
M: Alpha-CaMKII controls the growth of human osteosarcoma by
regulating cell cycle progression. Lab Invest. 87:938–950. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Plasilova M, Schonmeyr B, Fernandez J,
Clavin N, Soares M and Mehrara BJ: Accelerating stem cell
proliferation by down-regulation of cell cycle regulator p21.
Plastic Reconstr Surg. 123:149S–157S. 2009. View Article : Google Scholar
|
|
47
|
James AW: Review of Signaling Pathways
Governing MSC Osteogenic and Adipogenic Differentiation.
Scientifica. 2013:6847362013. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
An P, Tian Y, Chen M and Luo H:
Ca(2+)/calmodulin-dependent protein kinase II mediates transforming
growth factor-β-induced hepatic stellate cells proliferation but
not in collagen α1(I) production. Hepatol Res. 42:806–818. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Choi J and Husain M: Calmodulin-mediated
cell cycle regulation: New mechanisms for old observations. Cell
Cycle. 5:2183–2186. 2006. View Article : Google Scholar : PubMed/NCBI
|
