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Article

IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer

Corrigendum in: /10.3892/mmr.2019.9942
  • Authors:
    • Yidi Guo
    • Ying Zang
    • Lianzheng Lv
    • Feng Cai
    • Tingting Qian
    • Guoying Zhang
    • Quancheng Feng
  • View Affiliations / Copyright

    Affiliations: Department of Clinical Laboratory, Nanjing Integrated Traditional Chinese and Western Medicine Hospital Affiliated with Nanjing University of Chinese Medicine, Nanjing 210000, P.R. China, Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing 210000, P.R. China
  • Pages: 9035-9042
    |
    Published online on: October 10, 2017
       https://doi.org/10.3892/mmr.2017.7747
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Abstract

Interleukin-8 (IL-8) possesses tumorigenic and proangiogenic properties, and is overexpressed in many human cancer types. However, only few studies have demonstrated the mechanisms of action of IL‑8 regarding the ability to promote proliferation and to inhibit apoptosis in prostate cancer. Here, the aim of the present study was to investigate the effects of IL‑8 on the prostate cancer cell line and determine possible mechanisms underlying its effect. In this study, IL‑8 was shown to be significantly upregulated in prostate cancer compared with paired normal control tissues. The data showed that IL‑8 exhibits direct oncogenicity, which significantly induced cell proliferation, invasion and attenuated apoptosis in prostate cancer cells via signal transducer and activator of transcription 3/protein kinase B/nuclear factor‑κB signaling pathways. In conclusion, modulation of IL‑8 expression or its associated signaling pathway may provide a novel working mechanism of IL‑8 in prostate cancer, and a promising strategy for controlling the progression and metastasis of prostate cancer.
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1 

Siegel RL, Miller KD and Jemal A: Cancer statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI

2 

Watson PA, Arora VK and Sawyers CL: Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer. Nat Rev Cancer. 15:701–711. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Coleman RE: Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res. 12:6243s–6249s. 2006. View Article : Google Scholar : PubMed/NCBI

4 

Edlind MP and Hsieh AC: PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance. Asian J Androl. 16:378–386. 2014. View Article : Google Scholar : PubMed/NCBI

5 

González-Alonso P, Cristóbal I, Manso R, Madoz-Gúrpide J, García-Foncillas J and Rojo F: PP2A inhibition as a novel therapeutic target in castration-resistant prostate cancer. Tumor Biol. 36:5753–5755. 2015. View Article : Google Scholar

6 

Bratt O and Schumacher MC: Natural history of prostate cancer, chemoprevention and active surveillance. Acta Oncol. 50(Suppl 1): S116–S119. 2011. View Article : Google Scholar

7 

Dai Y, Qiao L, Chan KW, Yang M, Ye J, Ma J, Zou B, Gu Q, Wang J, Pang R, et al: Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis. Cancer Res. 69:4776–4783. 2009. View Article : Google Scholar : PubMed/NCBI

8 

Zmijewski MA and Slominski AT: Neuroendocrinology of the skin: An overview and selective analysis. Dermatoendocrinol. 3:3–10. 2011. View Article : Google Scholar : PubMed/NCBI

9 

Kim SW, Kim SM, Bae H, Nam D, Lee JH, Lee SG, Shim BS, Kim SH, Ahn KS, Choi SH, et al: Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades. Prostate. 73:296–305. 2013. View Article : Google Scholar : PubMed/NCBI

10 

Xie K: Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev. 12:375–391. 2001. View Article : Google Scholar : PubMed/NCBI

11 

Tanaka T, Bai Z, Srinoulprasert Y, Yang BG, Hayasaka H and Miyasaka M: Chemokines in tumor progression and metastasis. Cancer Sci. 96:317–322. 2005. View Article : Google Scholar : PubMed/NCBI

12 

Waugh DJ and Wilson C: The interleukin-8 pathway in cancer. Clin Cancer Res. 14:6735–6741. 2008. View Article : Google Scholar : PubMed/NCBI

13 

Yu J, Ren X, Chen Y, Liu P, Wei X, Li H, Ying G, Chen K, Winkler H and Hao X: Dysfunctional activation of neurotensin/IL-8 pathway in hepatocellular carcinoma is associated with increased inflammatory response in microenvironment, more epithelial mesenchymal transition in cancer and worse prognosis in patients. PLoS One. 8:e560692013. View Article : Google Scholar : PubMed/NCBI

14 

Li XJ, Peng LX, Shao JY, Lu WH, Zhang JX, Chen S, Chen ZY, Xiang YQ, Bao YN, Zheng FJ, et al: As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial-mesenchymal transition and activation of AKT signaling. Carcinogenesis. 33:1302–1309. 2012. View Article : Google Scholar : PubMed/NCBI

15 

Kido S, Kitadai Y, Hattori N, Haruma K, Kido T, Ohta M, Tanaka S, Yoshihara M, Sumii K, Ohmoto Y and Chayama K: Interleukin 8 and vascular endothelial growth factor-prognostic factors in human gastric carcinomas? Eur J Cancer. 37:1482–1487. 2001. View Article : Google Scholar : PubMed/NCBI

16 

Yuan A, Yang PC, Yu CJ, Chen WJ, Lin FY, Kuo SH and Luh KT: Interleukin-8 messenger ribonucleic acid expression correlates with tumor progression, tumor angiogenesis, patient survival, and timing of relapse in non-small-cell lung cancer. Am J Respir Crit Care Med. 162:1957–1963. 2000. View Article : Google Scholar : PubMed/NCBI

17 

Araki S, Omori Y, Lyn D, Singh RK, Meinbach DM, Sandman Y, Lokeshwar VB and Lokeshwar BL: Interleukin-8 is a molecular determinant of androgen independence and progression in prostate cancer. Cancer Res. 67:6854–6862. 2007. View Article : Google Scholar : PubMed/NCBI

18 

Kuai WX, Wang Q, Yang XZ, Zhao Y, Yu R and Tang XJ: Interleukin-8 associates with adhesion, migration, invasion and chemosensitivity of human gastric cancer cells. World J Gastroenterol. 18:979–985. 2012. View Article : Google Scholar : PubMed/NCBI

19 

Li M, Zhang Y, Feurino LW, Wang H, Fisher WE, Brunicardi FC, Chen C and Yao Q: Interleukin-8 increases vascular endothelial growth factor and neuropilin expression and stimulates ERK activation in human pancreatic cancer. Cancer Sci. 99:733–737. 2008. View Article : Google Scholar : PubMed/NCBI

20 

Shalapour S and Karin M: Immunity, inflammation, and cancer: An eternal fight between good and evil. J Clin Invest. 125:3347–3355. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Didonato JA, Mercurio F and Karin M: NF-κB and the link between inflammation and cancer. Immunol Rev. 246:379–400. 2012. View Article : Google Scholar : PubMed/NCBI

22 

He G and Karin M: NF-κB and STAT3-key players in liver inflammation and cancer. Cell Res. 21:159–168. 2011. View Article : Google Scholar : PubMed/NCBI

23 

Fan Y, Mao R and Yang J: NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer. Protein Cell. 4:176–185. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Grivennikov SI and Karin M: Inflammation and oncogenesis: A vicious connection. Curr Opin Genet Dev. 20:65–71. 2010. View Article : Google Scholar : PubMed/NCBI

25 

Grivennikov SI and Karin M: Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev. 21:11–19. 2009. View Article : Google Scholar : PubMed/NCBI

26 

Terlizzi M, Casolaro V, Pinto A and Sorrentino R: Inflammasome: Cancer's friend or foe? Pharmacol Ther. 143:24–33. 2014. View Article : Google Scholar : PubMed/NCBI

27 

Fang Y, Demarco VG and Nicholl MB: Resveratrol enhances radiation sensitivity in prostate cancer by inhibiting cell proliferation and promoting cell senescence and apoptosis. Cancer Sci. 103:1090–1098. 2012. View Article : Google Scholar : PubMed/NCBI

28 

Fang Y, Herrick EJ and Nicholl MB: A possible role for perforin and granzyme B in resveratrol-enhanced radiosensitivity of prostate cancer. J Androl. 33:752–760. 2011. View Article : Google Scholar : PubMed/NCBI

29 

Fujita Y, Okamoto M, Goda H, Tano T, Nakashiro K, Sugita A, Fujita T, Koido S, Homma S, Kawakami Y and Hamakawa H: Prognostic significance of interleukin-8 and CD163-positive cell-infiltration in tumor tissues in patients with oral squamous cell carcinoma. PLoS One. 9:e1103782014. View Article : Google Scholar : PubMed/NCBI

30 

Punyani SR and Sathawane RS: Salivary level of interleukin-8 in oral precancer and oral squamous cell carcinoma. Clin Oral Investig. 17:517–524. 2013. View Article : Google Scholar : PubMed/NCBI

31 

Herrero AB, Garcíagómez A, Garayoa M, Corchete LA, Hernández JM, San Miguel J and Gutierrez NC: Effects of IL-8 up-regulation on cell survival and osteoclastogenesis in multiple myeloma. Am J Pathol. 186:2171–2182. 2016. View Article : Google Scholar : PubMed/NCBI

32 

Perbellini O, Cioffi F, Malpeli G, Zanolin E, Lovato O, Scarpa A, Pizzolo G and Scupoli MT: Up-regulation of CXCL8/interleukin-8 production in response to CXCL12 in chronic lymphocytic leukemia. Leuk Lymphoma. 56:1897–1900. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Brew R, Erikson JS, West DC, Kinsella AR, Slavin J and Christmas SE: Interleukin-8 as a growth factor for human colorectal carcinoma cells in vitro. Cytokine. 12:78–85. 2000. View Article : Google Scholar : PubMed/NCBI

34 

Singh S, Singh AP, Sharma B, Owen LB and Singh RK: CXCL8 and its cognate receptors in melanoma progression and metastasis. Future Oncol. 6:111–116. 2010. View Article : Google Scholar : PubMed/NCBI

35 

Yao C, Lin Y, Chua MS, Ye CS, Bi J, Li W, Zhu YF and Wang SM: Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells. Int J Cancer. 121:1949–1957. 2007. View Article : Google Scholar : PubMed/NCBI

36 

Singh RK and Lokeshwar BL: Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherapeutic drugs. Mol Cancer. 8:572009. View Article : Google Scholar : PubMed/NCBI

37 

Karashima T, Sweeney P, Kamat A, Huang S, Kim SJ, Bar-Eli M, McConkey DJ and Dinney CP: Nuclear factor-kappaB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8. Clin Cancer Res. 9:2786–2797. 2003.PubMed/NCBI

38 

Kline M, Donovan K, Wellik L, Lust C, Jin W, Moon-Tasson L, Xiong Y, Witzig TE, Kumar S, Rajkumar SV and Lust JA: Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression. Leuk Res. 31:591–598. 2007. View Article : Google Scholar : PubMed/NCBI

39 

Karin M: Nuclear factor-kappaB in cancer development and progression. Nature. 441:431–436. 2006. View Article : Google Scholar : PubMed/NCBI

40 

Shrimali D, Shanmugam MK, Kumar AP, Zhang J, Tan BK, Ahn KS and Sethi G: Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer. Cancer Lett. 341:139–149. 2013. View Article : Google Scholar : PubMed/NCBI

41 

Profita M, Bonanno A, Siena L, Ferraro M, Montalbano AM, Pompeo F, Riccobono L, Pieper MP and Gjomarkaj M: Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism. Eur J Pharmacol. 582:145–153. 2008. View Article : Google Scholar : PubMed/NCBI

42 

Nguyen DP, Li J, Yadav SS and Tewari AK: Recent insights into NF-κB signalling pathways and the link between inflammation and prostate cancer. BJU Int. 114:168–176. 2013. View Article : Google Scholar

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Copy and paste a formatted citation
Spandidos Publications style
Guo Y, Zang Y, Lv L, Cai F, Qian T, Zhang G and Feng Q: IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942. Mol Med Rep 16: 9035-9042, 2017.
APA
Guo, Y., Zang, Y., Lv, L., Cai, F., Qian, T., Zhang, G., & Feng, Q. (2017). IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942. Molecular Medicine Reports, 16, 9035-9042. https://doi.org/10.3892/mmr.2017.7747
MLA
Guo, Y., Zang, Y., Lv, L., Cai, F., Qian, T., Zhang, G., Feng, Q."IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942". Molecular Medicine Reports 16.6 (2017): 9035-9042.
Chicago
Guo, Y., Zang, Y., Lv, L., Cai, F., Qian, T., Zhang, G., Feng, Q."IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942". Molecular Medicine Reports 16, no. 6 (2017): 9035-9042. https://doi.org/10.3892/mmr.2017.7747
Copy and paste a formatted citation
x
Spandidos Publications style
Guo Y, Zang Y, Lv L, Cai F, Qian T, Zhang G and Feng Q: IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942. Mol Med Rep 16: 9035-9042, 2017.
APA
Guo, Y., Zang, Y., Lv, L., Cai, F., Qian, T., Zhang, G., & Feng, Q. (2017). IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942. Molecular Medicine Reports, 16, 9035-9042. https://doi.org/10.3892/mmr.2017.7747
MLA
Guo, Y., Zang, Y., Lv, L., Cai, F., Qian, T., Zhang, G., Feng, Q."IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942". Molecular Medicine Reports 16.6 (2017): 9035-9042.
Chicago
Guo, Y., Zang, Y., Lv, L., Cai, F., Qian, T., Zhang, G., Feng, Q."IL‑8 promotes proliferation and inhibition of apoptosis via STAT3/AKT/NF‑κB pathway in prostate cancer Corrigendum in /10.3892/mmr.2019.9942". Molecular Medicine Reports 16, no. 6 (2017): 9035-9042. https://doi.org/10.3892/mmr.2017.7747
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