1
|
Hoy D, Brooks P, Woolf A, Blyth F, March
L, Bain C, Baker P, Smith E and Buchbinder R: Assessing risk of
bias in prevalence studies: Modification of an existing tool and
evidence of interrater agreement. J Clin Epidemiol. 65:934–939.
2012. View Article : Google Scholar : PubMed/NCBI
|
2
|
de Schepper EI, Damen J, van Meurs JB,
Ginai AZ, Popham M, Hofman A, Koes BW and Bierma-Zeinstra SM: The
association between lumbar disc degeneration and low back pain: The
influence of age, gender, and individual radiographic features.
Spine (Phila Pa 1976). 35:531–536. 2010. View Article : Google Scholar : PubMed/NCBI
|
3
|
Raj PP: Intervertebral disc:
Anatomy-physiology-pathophysiology-treatment. Pain Pract. 8:18–44.
2008. View Article : Google Scholar : PubMed/NCBI
|
4
|
Heathfield SK, Le Maitre CL and Hoyland
JA: Caveolin-1 expression and stress-induced premature senescence
in human intervertebral disc degeneration. Arthritis Res Ther.
10:R872008. View
Article : Google Scholar : PubMed/NCBI
|
5
|
Wang F, Cai F, Shi R, Wang XH and Wu XT:
Aging and age related stresses: A senescence mechanism of
intervertebral disc degeneration. Osteoarthritis Cartilage.
24:398–408. 2016. View Article : Google Scholar : PubMed/NCBI
|
6
|
Le Maitre CL, Freemont AJ and Hoyland JA:
Accelerated cellular senescence in degenerate intervertebral discs:
A possible role in the pathogenesis of intervertebral disc
degeneration. Arthritis Res Ther. 9:R452007. View Article : Google Scholar : PubMed/NCBI
|
7
|
van Deursen JM: The role of senescent
cells in ageing. Nature. 509:439–446. 2014. View Article : Google Scholar : PubMed/NCBI
|
8
|
Muñoz-Espín D and Serrano M: Cellular
senescence: From physiology to pathology. Nat Rev Mol Cell Biol.
15:482–496. 2014. View
Article : Google Scholar : PubMed/NCBI
|
9
|
Sharpless NE and Sherr CJ: Forging a
signature of in vivo senescence. Nat Rev Cancer. 15:397–408. 2015.
View Article : Google Scholar : PubMed/NCBI
|
10
|
Dimozi A, Mavrogonatou E, Sklirou A and
Kletsas D: Oxidative stress inhibits the proliferation, induces
premature senescence and promotes a catabolic phenotype in human
nucleus pulposus intervertebral disc cells. Eur Cell Mater.
30:89–102. 2015. View Article : Google Scholar : PubMed/NCBI
|
11
|
Volonte D, Zou H, Bartholomew JN, Liu Z,
Morel PA and Galbiati F: Oxidative stress-induced inhibition of
Sirt1 by caveolin-1 promotes p53-dependent premature senescence and
stimulates the secretion of interleukin 6 (IL-6). J Biol Chem.
290:4202–4214. 2015. View Article : Google Scholar : PubMed/NCBI
|
12
|
Kletsas D: Senescent cells in the
intervertebral disc: Numbers and mechanisms. Spine J. 9:677–678.
2009. View Article : Google Scholar : PubMed/NCBI
|
13
|
Acosta JC, Banito A, Wuestefeld T,
Georgilis A, Janich P, Morton JP, Athineos D, Kang TW, Lasitschka
F, Andrulis M, et al: A complex secretory program orchestrated by
the inflammasome controls paracrine senescence. Nat Cell Biol.
15:978–990. 2013. View
Article : Google Scholar : PubMed/NCBI
|
14
|
Kim KW, Chung HN, Ha KY, Lee JS and Kim
YY: Senescence mechanisms of nucleus pulposus chondrocytes in human
intervertebral discs. Spine J. 9:658–666. 2009. View Article : Google Scholar : PubMed/NCBI
|
15
|
Gruber HE, Ingram JA, Davis DE and Hanley
EN Jr: Increased cell senescence is associated with decreased cell
proliferation in vivo in the degenerating human annulus. Spine J.
9:210–215. 2009. View Article : Google Scholar : PubMed/NCBI
|
16
|
Zou H, Stoppani E, Volonte D and Galbiati
F: Caveolin-1, cellular senescence and age-related diseases. Mech
Ageing Dev. 132:533–542. 2011. View Article : Google Scholar : PubMed/NCBI
|
17
|
Parton RG and Simons K: The multiple faces
of caveolae. Nat Rev Mol Cell Biol. 8:185–194. 2007. View Article : Google Scholar : PubMed/NCBI
|
18
|
Smart EJ, Graf GA, McNiven MA, Sessa WC,
Engelman JA, Scherer PE, Okamoto T and Lisanti MP: Caveolins,
liquid-ordered domains, and signal transduction. Mol Cell Biol.
19:7289–7304. 1999. View Article : Google Scholar : PubMed/NCBI
|
19
|
Bartholomew JN, Volonte D and Galbiati F:
Caveolin-1 regulates the antagonistic pleiotropic properties of
cellular senescence through a novel Mdm2/p53-mediated pathway.
Cancer Res. 69:2878–2886. 2009. View Article : Google Scholar : PubMed/NCBI
|
20
|
Dai SM, Shan ZZ, Nakamura H, Masuko-Hongo
K, Kato T, Nishioka K and Yudoh K: Catabolic stress induces
features of chondrocyte senescence through overexpression of
caveolin 1: Possible involvement of caveolin 1-induced
down-regulation of articular chondrocytes in the pathogenesis of
osteoarthritis. Arthritis Rheum. 54:818–831. 2006. View Article : Google Scholar : PubMed/NCBI
|
21
|
Smolders LA, Meij BP, Onis D, Riemers FM,
Bergknut N, Wubbolts R, Grinwis GC, Houweling M, Koerkamp MJ Groot,
van Leenen D, et al: Gene expression profiling of early
intervertebral disc degeneration reveals a down-regulation of
canonical Wnt signaling and caveolin-1 expression: Implications for
development of regenerative strategies. Arthritis Res Ther.
15:R232013. View
Article : Google Scholar : PubMed/NCBI
|
22
|
Hou G, Lu H, Chen M, Yao H and Zhao H:
Oxidative stress participates in age-related changes in rat lumbar
intervertebral discs. Arch Gerontol Geriatr. 59:665–669. 2014.
View Article : Google Scholar : PubMed/NCBI
|
23
|
Nasto LA, Robinson AR, Ngo K, Clauson CL,
Dong Q, St Croix C, Sowa G, Pola E, Robbins PD, Kang J, et al:
Mitochondrial-derived reactive oxygen species (ROS) play a causal
role in aging-related intervertebral disc degeneration. J Orthop
Res. 31:1150–1157. 2013. View Article : Google Scholar : PubMed/NCBI
|
24
|
Zhang F, Zhao X, Shen H and Zhang C:
Molecular mechanisms of cell death in intervertebral disc
degeneration (review). Int J Mol Med. 37:1439–1448. 2016.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Ding L, Wu JP, Xu G, Zhu B, Zeng QM, Li DF
and Lu W: Lentiviral-mediated RNAi targeting caspase-3 inhibits
apoptosis induced by serum deprivation in rat endplate chondrocytes
in vitro. Braz J Med Biol Res. 47:445–451. 2014. View Article : Google Scholar : PubMed/NCBI
|
26
|
Sanger F and Coulson AR: A rapid method
for determining sequences in DNA by primed synthesis with DNA
polymerase. J Mol Biol. 94:441–448. 1975. View Article : Google Scholar : PubMed/NCBI
|
27
|
Ding L, Wu J, Li D, Wang H, Zhu B, Lu W
and Xu G: Effects of CCN3 on rat cartilage endplate chondrocytes
cultured under serum deprivation in vitro. Mol Med Rep.
13:2017–2022. 2016. View Article : Google Scholar : PubMed/NCBI
|
28
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
29
|
Ben-Porath I and Weinberg RA: The signals
and pathways activating cellular senescence. Int J Biochem Cell
Biol. 37:961–976. 2005. View Article : Google Scholar : PubMed/NCBI
|
30
|
Jeong SW, Lee JS and Kim KW: In vitro
lifespan and senescence mechanisms of human nucleus pulposus
chondrocytes. Spine J. 14:499–504. 2014. View Article : Google Scholar : PubMed/NCBI
|
31
|
Feng C, Liu H, Yang M, Zhang Y, Huang B
and Zhou Y: Disc cell senescence in intervertebral disc
degeneration: Causes and molecular pathways. Cell Cycle.
15:1674–1684. 2016. View Article : Google Scholar : PubMed/NCBI
|
32
|
Chen JW, Li B, Yang YH, Jiang SD and Jiang
LS: Significance of hypoxia in the physiological function of
intervertebral disc cells. Crit Rev Eukaryot Gene Expr. 24:193–204.
2014. View Article : Google Scholar : PubMed/NCBI
|
33
|
Zhou BR, Guo XF, Zhang JA, Xu Y, Li W, Wu
D, Yin ZQ, Permatasari F and Luo D: Elevated miR-34c-5p mediates
dermal fibroblast senescence by ultraviolet irradiation. Int J Biol
Sci. 9:743–752. 2013. View Article : Google Scholar : PubMed/NCBI
|
34
|
Shin JH, Jeon HJ, Park J and Chang MS:
Epigallocatechin-3-gallate prevents oxidative stress-induced
cellular senescence in human mesenchymal stem cells via Nrf2. Int J
Mol Med. 38:1075–1082. 2016. View Article : Google Scholar : PubMed/NCBI
|
35
|
Kiyoshima T, Enoki N, Kobayashi I, Sakai
T, Nagata K, Wada H, Fujiwara H, Ookuma Y and Sakai H: Oxidative
stress caused by a low concentration of hydrogen peroxide induces
senescence-like changes in mouse gingival fibroblasts. Int J Mol
Med. 30:1007–1012. 2012. View Article : Google Scholar : PubMed/NCBI
|
36
|
Sun C, Wang N, Huang J, Xin J, Peng F, Ren
Y, Zhang S and Miao J: Inhibition of phosphatidylcholine-specific
phospholipase C prevents bone marrow stromal cell senescence in
vitro. J Cell Biochem. 108:519–528. 2009. View Article : Google Scholar : PubMed/NCBI
|
37
|
Kortum RL, Fernandez MR, Costanzo-Garvey
DL, Johnson HJ, Fisher KW, Volle DJ and Lewis RE: Caveolin-1 is
required for kinase suppressor of Ras 1 (KSR1)-mediated
extracellular signal-regulated kinase 1/2 activation,
H-RasV12-induced senescence, and transformation. Mol Cell Biol.
34:3461–3472. 2014. View Article : Google Scholar : PubMed/NCBI
|